Sedentary overweight people get insulin boost from short term exercise; CVD risks trend down
... change in the ZERO group in this measure of liver function and endothelium inflammation, which some research has shown to correlate with certain heart problems. Mitchell noted that the study involved considerable time commitment over a short period and that there was good oversight and controls, ...Embryonic stem cells correct congenital heart defect in mouse embryos
...ring defective cells and restore their capacity to function normally. Researchers at Memorial Sloan-Kettering Cancer Center report that 15 embryonic stem cells injected into early embryos of mice whose hearts were genetically predisposed to develop a lethal defect, rescued the heart from developing the disord...Emory chemists develop bacteria that may help decaffeinate coffee
...ng challenge was to couple this binding to a vital function of the bacteria -- the production of a protein. To do this, the Emory team created a new sequence of RNA known as a "riboswitch." In bacteria, riboswitches normally recognize essential molecules, such as vitamin B12, and switch the production of pro...Study describes basic mechanism in cell growth control involving damaged DNA
...in motion when a protein is "misfolded" and cannot function properly. Degradation also occurs when proteins o...ded. "This provides an explanation of how DDB1 may function to ensure the genetic stability and prevent cancer cell growth," said Xiong. "Our findings suggest t...Cells in retina found to behave like soap bubbles
... they are located in a living thing and what their function is." In investigating the physical basis of biolog...w, who with Hayashi has been studying the form and function of the retina for years. "This experiment illustrates the importance of mathematics and physics in b...New method identifies chromosome changes in malignant cells
...tistics to questions concerning the regulation and function of genes. In September, Technology Review magazine, which is published by the Massachusetts Institute of Technology, announced that it included Troyanskaya in its annual list of 100 top innovators from around the world. The magazine cited her for cre...Technology award presented to Weizmann Institute scientist
...ll in the very early stages, and can thus far only function in test tubes, Shapiro and his research team envision future biomolecular devices that may be injected directly into the human body to detect and prevent or cure disease. Award winners are chosen by their peers in the WTN. The Network's membership ...Time-lapse movies show brain cells move like a two-stroke engine
...onfirmed these results. To further investigate the function of mPar6-alpha, the researchers created cells with either too much or too little of the protein. In both cases the cells sat motionless on their glial fibers. "By two different methods, overexpression and physically getting rid of the protein, we get...Scientists explain how morphogens work
...e understanding of the mechanisms that control the function of morphogens," Lin said. "In order to treat disea... Dr. Lin focuses on TGF beta family molecules that function as morphogens. His interest is in learning how the TGF beta morphogen works. Developmental biol......o, he and other scientists have tried to learn its function scientists call it an "orphan" receptor because they don't know what protein links up with it. So a team led by Chang, director of George Whipple Laboratory for Cancer Research at the University of Rochester Medical Center, knocked out the gene in m...Research gaining momentum by silencing genes
...he new RNAi technology, they are able to study the function of genes with the aid of specially designed fragme... concentrating on the search for the genes and the function of the proteins involved. Not only will this lead to new insights into the functioning of plant cell...UCSD medical researchers use brain cell transplants to correct muscle spasms after aneurysm surgery
...nsplants displayed a progressive recovery of motor function and a decrease in spasticity in the lower extremit...eive transplants exhibited no improvement in motor function or spasticity. A post-mortem study of the animals showed a robust growth of neurons and an increase...UCLA scientists discover new way to fix defective gene
...Unstable proteins create abnormal cells that can't function properly, producing all of the neurological and im...ls had converted to normal appearance and begun to function normally. The cells started churning out ATM protein, which provides energy by switching on other c...Excess dietary fat accelerates breast cancer by altering the activity of a group of genes
...urth of which is a sequence with a totally unknown function (known as EST Rn.32385), thereby accelerating the proliferation of tumours. The scientists have reached these conclusions from results, obtained using microarrays, that compare the expression of 6,000 genes in breast cancer tumours in animals fed...Rutgers is on the 'NIH Roadmap'
...of living cells. Understanding protein structure, function and interactions can lead to an understanding of the molecular basis of disease. Principal investigator Ronald Levy, co-director of the BioMaPS Institute, and co-principal investigators Gaetano Montelione, director of the NESG, and Helen Berman, dire...New version of tumor-suppressor linked to progression of childhood cancer
...oter for a molecule that was previously thought to function exclusively as a cancer suppressor in neuroblastom...art, by interfering with the normal anti-oncogenic function of TrkA. The researchers conclude that formation of TrkIII represents a tumor-promoting switch in NB...Lag-3 gene dampens immune responses by controlling regulatory T-cell function
..."We'd like to put that kind of control over immune function into the hands of physicians," Vignali said. ...OHSU study: Bacterial switching mechanism key to survival
...es on bacterial systems. If you can understand the function of the players, which control critical basic functions in bacteria, they offer the opportunity to develop novel antibiotics, which disrupt those functions." In the case of the Cell study, an antibiotic could be developed to disrupt the HPr-CcpA inter...New DNA repair enzyme makes mistakes to save lives of cells
... turn determine all aspects of a cell's structure, function and movement. Each strand consists of nucleotides ...ings, it seems that an impairment or lack of POL-Q function may be tied to a cancer-prone pathway. This is certainly worth further investigation," commented Dr....Mitochondrial mutation linked to blood pressure and cholesterol problems
...is independent evidence that altered mitochondrial function plays a role in insulin resistance and high trigly... a clear link to specific disorders, mitochondrial function is known to decline with age in normal people and may be contributing to these common traits in the ...