VYTORIN (TM) superior again to Lipitor at lowering LDL (bad) cholesterol
...as well tolerated and had lower incidence of liver function elevations than Lipitor Both VYTORIN and Lipitor ...YTORIN 10/80 mg should receive an additional liver function test prior to and three months after titration and periodically during the first year. Due to the u...Is the zebra fish leading us to new therapies?
... aquarium fish can be used to aid the study of the function of human genes. That this investment is reaping returns is evident from the study that VIB researchers at the Catholic University of Leuven are publishing today in the renowned journal Nature . They have shown for the first time that new blood vesse...Fat buildup found in hearts of obese or diabetic heart failure patients
...ients in the study volunteer to have their cardiac function analyzed and to provide a small sample of thigh mu...eight loss after surgery results in improved heart function and decreased levels of lipids in muscle tissue. Earlier research by Taegtmeyer showed that diabetes...Ethical paradigm: Relating embryonic stem cell use to organ donation
... a fully developed human. At the point that brain function is irretrievably lost, even if other cells and organs remain alive, humans are considered organismically dead. At this time organs and tissues may be harvested as needed and allowed by . The authors propose a similar mechanism might be used for embr...UGA scientist Moran receives $2.6 million from Gordon and Betty Moore Foundation for marine research
...attaining new knowledge regarding the composition, function and ecological role of microbial communities in the world's oceans. Funding strategies include supporting Gordon and Betty Moore Foundation investigators, linking scientists in related fields, establishing intern programs and supporting select resea...Gene that blocks free radical damage protects against emphysema
...t and cell-protective genes in the lung that might function together to protect the lung from cigarette smoke-induced emphysema. These data suggest that the Nrf2 pathway provides protection from emphysema by turning on antioxidants and suppressing inflammation and cell death in the lung....JCI table of contents November 1, 2004
...commentary places this study in the context of the function of the ABCA1 transporter and its impact on HDL pro...t and cell-protective genes in the lung that might function together to protect the lung from cigarette smoke-induced emphysema. These data suggest that the Nrf...Mutations in transporter protein effect HDL levels in the general population
...commentary places this study in the context of the function of the ABCA1 transporter and its impact on HDL production along with studies of the genetics and molecular mechanisms relating to Tangier disease....First human trial of bioartificial kidney shows promise for acute renal failure
...oducts, and cannot provide the cytokine regulation function of living cells. Traditional therapy for patients with acute or chronic renal failure involves dialysis or kidney transplant, both of which have limitations. Humes and his colleagues began developing this technology a decade ago, identifying the adul...BU chemist to map DNA's surface, uncovering details that will show how structure abets function
...ehensive catalog of elements crucial to biological function in the roughly 98 percent of the human genome that does not code for proteins. ENCODE researchers are bringing their individual investigations to bear on a particular 1 percent of the genome selected by ENCODE coordinators at NHGRI. Tullius's resea...Research team discovers possible genetic mechanism behind congenital heart defects
...ronto (U of T). "When we completely suppressed the function of the Baf60c protein, there were dramatic cardiov... of Excellence. Using a novel way of reducing gene function called in vitro RNAi, the team developed mouse models with different levels of the protein. They wer...Growth factors confer immortality to sperm-generating stem cells
...erfully robust diagnostic system for analyzing the function of individual genes. For medicine, it opens up a new chapter in fertility medicine." Spermatagonial stem cells and the hematopoietic stem cells that generate new blood cells are the only types of adult stem cells that can be positively identified u...Structure of new DNA enzyme family member found
...o are trying to understand how proteins evolve and function by looking at their structural features, have unco...h group's work. "Often, two proteins with the same function have no sequence similarity," says Ealick, whose research group works with crystallized proteins, th...International Rice Functional Genomics meeting in Tucson Nov. 15-17
...rch on the rice genome: the quest to determine the function of all of the approximately 50,000 genes in rice. ...hose rice genes do. Right now researchers know the function of only about 500 rice genes-- just 1 percent of the rice genome. Learning how the genes act inside ...Crucial evolutionary link points to origins of modern cells
...ort network inside cells that is essential for the function of cells ranging from yeast to plants to humans. This transportation network, called the endomembrane system, and the presence of a nucleus that contains the cell's DNA, are among the features that distinguish eukaryotic cells -- which make up pla...UNC Lineberger researchers identify molecular markers of aging
... The study suggests that the important anti-cancer function of these proteins to limit cellular growth might in turn cause aging. "Proliferation of cells is important in the repair and regrowth of tissues. In fact, we grow old in part because our bodies' ability to regenerate tissues decreases a...Norman D. Newell to receive Legendary Geoscientist Award
...and perspectives in the interpretation of form and function of fossil invertebrates. Several decades later he brought to completion the two multi-authored Bivalvia volumes of the Treatise on Invertebrate Paleontology. These books still serve as the single most important reference on fossil bivalve mollusks. A...Mayo researchers define celecoxib pathways and mechanisms for tumor reduction
...d expression of the Bax protein, which is known to function within the pro-apoptotic cell mechanism. Further, the introduction of celecoxib resulted in reduced activity of an anti-apoptotic protein, Akt, known to promote cell survival. Generally, COX-2 works by regulating the production of prostaglandins ...A new target for control of obesity
...ways present in these cells. The physiological function of Shp2 is largely unknown. Whether it is active ...ound that in adult neuoronal cells, it's important function is to control metabolism. This hypothesis will be tested further, but it appears to present a targe...Molecular switch provides clues to remarkable adaptability of human pathogen
...e observation that a number of genes with no known function are regulated by RetS in coordination with established virulence determinants suggests that these genes may code for previously undiscovered virulence factors. Andrew Goodman, Bridget Kulasekara, Arne Rietsch, Dana Boyd, Roger Smith, and Stephen L...