Tag: "functionally" at biology news

Researchers: Deep sleep short-circuits brain's grid of connectivity

...that mediate perception, thought and action become functionally disconnected. Tononi and his team observed the disconnect when brief, magnetically generated pulses of electricity were directed to specific regions of the brain. The pulses stimulated an electrochemical response from the targeted cells, which, when ...

Researchers discover new route to hemoglobin synthesis

...s of grx5 in zebrafish, yeast, mice and humans are functionally equivalent. "It seemed like the whole process was evolutionarily conserved," said Zon. "But the difference is that yeast do not make hemoglobin. So we needed to figure out a mechanism that would explain why these fish that have problems making iron-s...

No small feat: First ever gene therapy success for muscular dystrophy achieved

... mini-agrin. Once produced, the mini-agrin protein functionally took the place of the laminin alpha-2 protein by binding to the key proteins on either end, thus restoring the cell's outside scaffolding and reestablishing the missing link to key structures inside the cell. Clearly, the authors are most excited abo...

Protein prevents tissue injury but encourages tumor growth

...the wild-type mice. "The human Bcl-xL protein is functionally identical to the mouse protein, so the same effects are expected in humans," Weintraub says. "If you took a population of people, you would likely see variation in Bcl-xL levels from person to person. In addition, Bcl-xL levels in each person are alt...

Landmark comparative genomics study highlights the importance of 'junk' DNA in higher eukaryotes

... as easy as possible for researchers to home in on functionally important DNA sequences."...

Meaningless sex? Male mounting reduces sexual promiscuity of females

...delivery of little or no sperm are not necessarily functionally meaningless but may instead have an important evolutionary significance....

Scientists uncover new clues about brain function in human behavior

... area did not activate for either task and was not functionally linked to the amygdala, as it was in healthy contr...s Syndrome, but we didn't know what role it played functionally in the disorder; it is now clear that this area can play a major role in producing social behavioral...

Fish and chips: A fast track to understanding blood development

...ene expression analysis using gene arrays has been functionally validated by high-throughput true functional analysis in a model organism," says Verfaillie. With this approach, new studies may zero in on genes with central roles in other kinds of human development....

Bioinformatics reveals new gene regulation system

...tional clustering takes advantage of the fact that functionally related gene sequences (such as the genes for Nrd and its transcription factor) frequently inhabit the same 'neighborhood' of the chromosome. "If you are looking in one genome, many genes will be neighbors by coincidence," Gelfand noted. "But if tw...

Scripps research scientists solve structure of a critical innate immune system protein

...rapidly detect invading pathogens. "We don't know functionally how TLR proteins work," says Professor Ian Wilson, D.Phil., who is a professor in the Department of Molecular Biology at The Scripps Research Institute and a member of the The Skaggs Institute for Chemical Biology. "but But the structure has given us...

Discovery offers promising lead in prostate cancer diagnosis

...ection of prostate cancer by providing a novel and functionally relevant biomarker. However, the exploration of the therapeutic potential of ERG is equally important," said Dr. Robert Vessella from the University of Washington, Seattle, who is one of the pioneers in developing new diagnostic and prognostic cellul...

University of Chicago study overturns conventional theory in evolution

...lled synonymous mutation (Ks). These mutations are functionally neutral, which means natural selection is not a fa...ns are accepted at the same rate since the gene is functionally irrelevant. For a gene that is highly functional and important for the organism, its Ka/Ks ratio is ...

Love's all in the brain: fMRI study shows strong, lateralized reward, not sex, drive

... results suggest that romantic love does not use a functionally specialized brain system. It may be produced, instead, by a constellation of neural systems that converge onto widespread regions of the caudate where there is a flexible combinatorial map representing and integrating many motivating stimuli. "This...

Researchers find first gene for inherited testicular cancer in mice

...rols inherited susceptibility. This gene and other functionally related genes might be used to diagnose at-risk individuals for more careful monitoring. And perhaps by understanding the role of RNA editing in the biology of the cancer stem cells we can develop improved therapeutics to treat and perhaps prevent th...

Scientists identify genes responsible for 'black rot' disease in vegetables

...inversions, insertions, and deletions. In order to functionally characterize Xcc and identify genes implicated in its pathogenicity, the researchers then screened an Xcc transposon insertional mutant library in its host plant (cabbage). They screened a total of 16,512 Xcc mutants on individual cabbage plants and...

Molecular spies illuminate drug resistance proteins

...milar to the previous crystal structures except in functionally important details, the spies were able to reveal something the crystal structures couldn't the opening and closing of the transporter in response to energy expenditure. Multidrug transporters like MsbA pump molecules out of the cell using the energ...

Monkeys adapt robot arm as their own

...ments Mikhail analyzed very carefully what happens functionally to the brain cells and the brain cell ensembles in multiple brain areas during this transition. "And basically we were able to show clearly that a large percentage of the neurons become more 'entrained' -- that is, their firing becomes more correlate...

JCI table of contents June 1, 2005

...cus pneumoniae, a powerful pathogen, to induce two functionally and morphologically distinct forms of programmed cell death in endothelial cells. One pathway is classical apoptosis and the other is an apoptotic-like pathway mediated by bacterial toxins. This study advances our understanding of bacteria-induced ...

Can our genes tell the story of our divergence?

...genes touched by positive selection will show more functionally significant molecular changes than unaffected regions. In the new study, Rasmus Nielsen, Michele Cargill, and their colleagues compared 13,731 genes in humans to their equivalents in chimps to find positively selected genes in both species. Niels...

Return to normalcy

...erexpressed MDM2. In both tumor types, p53 may be functionally inactivated and this promotes tumorigenesis," explains Dr. Donehower....

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(Date:10/16/2014)... monocultures can be cultivated efficiently, they are anything ... caused by monoculture cultivation is becoming increasingly evident. ... crop form and are regarded as the sole ... – quite wrongfully, finds Bernhard Schmid, an ecology ... a novel form of agriculture and forestry. After ...
(Date:10/15/2014)... pandemic risk from strains of influenza virus increases with ... to become complacent that the most substantial threats have ... Influenza pandemics arise when a new virus strain – ... – spreads in the human population. There have been ... worst of which – the 1918 Spanish Flu – ...
(Date:10/15/2014)... NXT-ID, Inc. (NASDAQ: NXTD and NXTDW) ... growing mobile commerce market releases photos and video of the recent ... October 13 th . Gino Pereira , ... angel investor Mr. Chad A. Verdi rang the bell.  ... his investors and employees "for their work and dedication in bringing ...
Breaking Biology News(10 mins):Plant communities produce greater yield than monocultures 2Plant communities produce greater yield than monocultures 3Scientists 'must not become complacent' when assessing pandemic threat from flu viruses 2Photo Release: NXT-ID Inc. Rings Opening Bell of the NASDAQ Stock Market October 13th 2Photo Release: NXT-ID Inc. Rings Opening Bell of the NASDAQ Stock Market October 13th 3
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