Research shows skeleton to be endocrine organ
...levels of osteocalcin activity were prevented from gaining weight or becoming diabetic even when they ate a high fat diet. Analysis of mice lacking the osteocalcin protein showed that they had type 2 diabetes, increased fat mass, a decrease in insulin and adiponectin expression, and decreased beta-cell proli...European Science Foundation's Forward Look reaches out beyond the endless frontiers
... This strenuous but carefully planned procedure is gaining creditability from both the science community and policy makers as all outputs from Forward Looks are subjected to proper external peer review. The impact of such an approach is evident in the reception of a previous Forward Look exercise on Nanomedi...Secret life of elephant seals not secret anymore!
...he scientists could determine where the seals were gaining fat (and becoming more buoyant) and where food was harder to find and the animals lost fat. These measurements have allowed us for the first time to make circumpolar maps of the areas that provide good foraging for seals, and areas where conditions...Monell researchers find metabolic defect in liver that can lead to obesity
..., the obesity-prone rats overate and became obese, gaining 36% more weight than resistant animals. Fat oxidation was further compromised due to a decreased ability to make CPT1A, the liver enzyme responsible for transporting fat into mitochondria. The inherited propensity to gain weight when eating a hig...Restless legs genetics on the move
...offers researchers completely new perspectives for gaining an understanding of the cell-biology involved in the development of RLS. ...Jefferson scientist's patent dramatically improves
...involve DNA analysis. The process has already been gaining acceptance and use internationally. Its becoming more widespread, but like anything in science, it will take time to become a fixture, he says. Scientists are like most people: we dont necessarily like to change....NY Stem Cell Foundation's 2nd Annual Translational Stem Cell Research Conference
...versations at this years conference will be key to gaining a better understanding of what is on the horizon. The New York Stem Cell Foundation conference is co-sponsored by the Albert Einstein College of Medicine, Columbia University Medical Center, the Helen and Martin Kimmel Center for Stem Cell Biology at...5 OHSU faculty members singled out for honors
...onal Science Foundation since 1986 has focused on gaining a better understanding of how embryonic cells modify general cellular mechanisms to generate the earliest features of the embryos body plan. He currently is working on understanding cytoskeletal and membrane dynamics during embryonic compaction when...From the corner of the eye: Paying attention to attention
...elements that make up the cortical circuit, we are gaining a view of the biological underpinnings of attention that is unprecedented in its level of detail," says post-doctoral researcher Jude Mitchell, Ph.D., lead author on the study. He adds that, while there is much more work ahead, "if we can understand ...Generalized reciprocity in rats
...likely. In this study, Norway rats received help gaining food from a partner who pulled a stick to produce the food. Rats could therefore be grouped into two classes: those that had previously received help and those that had not. The rats who had previously been helped were then more likely to help anothe...How the Biotech Revolution Is Changing the Way We Fight Disease
...f our body and the therapeutic techniques that are gaining in sophistication and effectiveness every year. From heart disease to AIDS and cancer, he helps you understand how the tools of biotechnology are being used to combat our most common afflictions. Stephenson examines a wide variety of health threats a...Cigarette smoke alters DNA in sperm, genetic damage could pass to offspring
...e of trying to conceive. Among the next steps in gaining a better understanding of the germline genetic health conse-quences of smoking, Yauk and her colleagues plan to study how altered DNA manifests itself in the children and grandchildren of male mice that are exposed to firsthand smoke. They also plan ...UGA study reveals function of ubiquitous yet poorly understood microorganisms
...he other two branches. But scientists are just now gaining a fuller understanding of what archaea do in an ecological sense to make a living. A new study led by University of Georgia researchers and announced on Wednesday at the American Society for Microbiology meeting in Toronto finds that crenarchaeot...A close-up on pancreatic disease: How do we improve the odds?
...ficant challenges in treating pancreatic cancer is gaining a clear diagnosis at an early stage. Imaging technologies have improved drastically during the past decade, but are still limited in terms of image clarity and ability to differentiate among similar conditions. Because changes in chronic pancreatit...Immune antibodies penetrate neurons to clear Alzheimer's-linked amyloid
...ith Alzheimer's can cross the blood-brain barrier, gaining access to the brain," Dr. Gouras explains. He remains one of the leading authorities on beta-amyloid plaques because of earlier work on its deposition and accumulation between neurons. "One of the things those earlier immunotherapy studies taught u...A new wrinkle in evolution -- man-made proteins
...om the set of proteins nature ultimately chose" By gaining a better understanding of these questions, we hope to one day create new tailor-made catalysts that can be used as therapeutics in molecular medicine or biocatalysts in biotechnology." The building blocks of proteins are 20 different amino acids th...Clock gene plays role in weight gain, study finds
...l mice on the high fat diet, however, "ballooned," gaining more than twice the weight of the Nocturnin-deficient mice. And when the mice were dissected, the researchers discovered that the normal mice had, as expected, large concentrations of fat on their livers, whereas the altered mice had normal levels of...Scientists seek useful traits in wild cottons
...rture the plant while it is establishing roots and gaining strength." Treated seed and insecticides applied in the furrow at planting help farmers combat thrips, but these methods are expensive and often only provide a three-week window of protection against this hungry pest, Arnold said. Arnol...Molecule that destroys bone also protects it, new research shows
...ost defense versus pathology is very important for gaining a fundamental understanding of the immune system," Gaffen said, "but also because the consequences of therapies that target these cytokines need to be understood."...Unstable leukemia stem cells may predispose patients to drug resistance
.... These considerations highlight the importance of gaining further understanding of the control of DNA replication and repair in the leukemic stem cells from patients with chronic phase [chronic myeloid leukemia] in future efforts to devise therapies with curative potential, the authors write. In an accom...