Tag: "genes" at biology news
Herpes virus hijacks DNA repair process
... molecules, researchers turned to mice lacking the genes
for ATM and H2AX, the damage response proteins activated by infection. When they infected cells from these mice with murine herpes virus, its ability to reproduce was again curtailed. How DNA damage response benefits viral replication is still a myst...
5.9 million award gives UK aging research a new lease on life
...ecent research has revealed that changes to single genes
can make animals live longer, by maintaining health and delaying the onset of ageing-related diseases, such as cancer, diabetes and cardiovascular disease. "What is particularly exciting about this approach is that altering an animal's genetic make...
'Wurst' ensures that the respiratory system works
...is common practice for the discoverers to name new genes
or proteins for official usage. "The name we have chosen derives from the effect that the respective molecule develops when it does not work." Together with his team, consisting of Dr. Matthias Behr and Christian Wingen as well as the Gttingen-bas...
New findings challenge established views about human genome
... the genome contains very little unused sequences; genes
are just one of many types of DNA sequences that h...ll need to rethink some long-held views about what genes
are and what they do, as well as how the genomes functional elements have evolved. This could have s...
University of Washington researchers play leading role in major study of human genome function
... elements" that contain instructions for switching genes
on or off, and for controlling how DNA is packaged and replicated within a human cell. Scientists believe these DNA sequences may play a very important role in some diseases, such as prostate or colon cancer. The UW was a leading institution among...
The wider view from a detailed focus
...ests that "our perspective of transcription and genes
may have to evolve," the researchers state, not...on-base genome, peppered with some 22,000 discrete genes
and the sequences that regulate their activity. These were estimated to occupy perhaps 3-5% of th...
Other highlights in JNCI, June 12
...o 15 months. Researchers hope that identifying the genes
that control the progression of the disease will help them develop new therapies. Samuel Ng, Ph.D., of the University of Hong Kong and colleagues analyzed the gene expression of CCRK in human glioma cell lines, in samples from glioma patients and ...
News tips from the Journal of Neuroscience
...tian A. Hbner, and Thomas J. Jentsch The hunt for genes
that increase susceptibility to disease is fraught with twists and turns. Heterozygous mutations in the plasma membrane chloride channel ClC-2 have been linked to human epilepsy in three families. However, Blanz et al. found a quite different phenoty...
UCR biologists unravel the genetic secrets of black widow spider silk
...article , they describe their work to identify the genes
encoding the two key proteins, named MaSp1 and MaSp2, and determine the genes
complete DNA sequences. The UCR Office of Technology Commercialization has filed a patent applicati...
A fly lamin gene is both like and unlike human genes
... The fruit fly Drosophila melanogaster has 2 lamin genes
that are expressed in A- and B-type patterns, and ...agues, among others, have shown that the fly lamin genes
are more closely related to each other than to mammalian lamin genes. While the independent evolutio...
Study shows lizard moms dress their children for success
...e. Whether they get stripes or bars depends on the genes
for other traits. "This is the first example in ...ebulous thing to study, because you know there are genes
for these traits, and it's really hard to tell the maternal effects apart from the effects of the ge...
Physicist cracks women's random but always lucky choice of X chromosome
...ave much wider implications as at least 10% of our genes
may behave in similar ways as mechanism that "choo...n begins to gather around both of the XIST suicide genes
on each X Chromosome. This starts a race between the two build ups of protein. Inevitably one of the...
Breakthrough developments in rheumatoid arthritis reported
...regersen has finally closed the circle between key genes
identified in his laboratory at the Robert S. Boas...an a 1,000 patients with rheumatoid arthritis. The genes
will help tell the story of how the immune system works to create specific antibodies that in turn i...
'Lucky 13' as new gene discovery offers further hope for childhood blindness
...ical trials for a gene therapy involving injecting genes
into the eye of patients with LCA to restore their...fects in the retina. "We already know of a dozen genes
which, when mutated, cause LCA," says Professor Chris Inglehearn from the Leeds Institute of Molecul...
Food safety begins as vegetables grow
... shown that pathogens like Salmonella use specific genes
to colonize plants, creating an active interaction with the plant surface. "When this happens, the bacteria become almost inseparable from the vegetable," she said. Barak and other APS members will present their latest food safety research and des...
Sensitivity to diverse range of chemotherapeutic drugs linked to common pathway
...ll, published by Cell Press, identifies individual genes
that are associated with resistance to chemotherap...member of the taxane family, as expected, involves genes
that impair drug-induced mitotic arrest following knockdown. Silencing of these genes
in many cases ...
U-M researchers discover gene switched off in cancer can be turned on
... cancer to develop. But cancers also arise because genes
that control growth are turned off. While researchers can use these turned-off genes
to identify or monitor cancer, currently no treatments actually target these genes. U-M researcher...
Tumor vessels identified by unique molecular markers
...essels revealed several organ-specific endothelial genes
that could potentially aid in the delivery of mole...cific anatomical sites. The study also revealed 13 genes
that are selectively overexpressed in tumor blood vessels. Although the function of most of the newl...
Researchers identify fifth gene responsible for Joubert syndrome
...le for Joubert syndrome, and continue to study how genes
work together to build and maintain the brain, retina and kidney....
Cancer stem cells can go it alone
...ell system will also allow researchers to identify genes
and proteins that will help with the search for human breast cancer stem cells in the future. As we learn more about tumor formation at the single cell level in tissue, we may be able to specifically target cancer stem cells for destruction while lea...
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