Scientists decode genome of oral pathogen
...mmonwealth University researchers have decoded the genome of a bacteria normally present in the healthy huma...VCUs vice president for research. "Analysis of the genome revealed a surprising number of proteins on the S. sanguinis cell surface that may be new targets fo...Picky-eater flies losing smell genes
...me that biologists have been able to compare whole genome sequences from closely related insects that differ dramatically in their ecology," she said. McBride also compared the genes of these two flies to another close relative, the classic lab fruit fly Drosophila melanogaster. She discovered that not on...Bony vertebrate evolution: Elephant sharks closer to humans than teleost fish
...k. Unlike teleost fish genomes, the elephant shark genome does not seem to have experienced an additional ro...phant shark as a useful "model" cartilaginous fish genome for understanding vertebrate genome evolution. ...Study identifies multiple genetic risk factors for prostate cancer
...tors are clustered in a single region of the human genome on chromosome 8 and powerfully predict a man's pro...cally tested genetic changes in this region of the genome in roughly 7,500 African American, Japanese American, Native Hawaiian, Latino, and European American...Detecting poisons in nectar is an odour-ous task for honeybees
...e or scent with food. The newly-sequenced honeybee genome has revealed that honeybees do not have as many genes for taste receptors as other animals of a similar size, such as flies and mosquitoes. This prompted scientists to think that perhaps honeybees had a reduced need to detect and learn about toxins,......neer in Hyderabad, India, searched the Arabidopsis genome for genes that allowed plants to react to chloroplast damage. His search turned up GUN1, short for genomes uncoupled 1, a nuclear encoded protein he could trace to specific domains within chloroplasts. No matter under which kind of stress the chlo...Biologists call for better choice of model organisms in 'evo-devo'
...s that allow us to calculate how much an organisms genome has changed over time, when making assessments about how much an animal resembles its ancestor, because this information can be helpful in estimating how much an organisms phenotype has changed." Dr Wills added: "Establishing criteria for choosing ...NIH neuroscience microarray consortium launches high-throughput genotyping services
...roarray technologies for scanning the entire human genome and all of the genes for which it encodes." Each of the four members of the Consortium offer specialized services. The Translational Genomics Research Institute (TGen) offers both expression profiling and SNP genotyping on Affymetrix Genechips. UCL...Chromosomal microarray analysis proves accurate
...p of chromosomes in a particular part of the human genome (genetic blueprint). In areas of the genome, the...al group of patients studied. This high resolution genome analysis promise to transform the practice of clinical genetics," said Beaudet. More important, th...Why some people are more attractive than others
...enetic diversity in disease defence regions of the genome and therefore better prospects of passing disease resistance to their offspring had a number of physical features which women found attractive. The research involved testing men for genetic diversity and showing photographs of them to women, who ...Genomics throws species definition in question for microbes
...of species. The acquisition of draft-quality genome sequences for all type strains to help advance the integration of genomic information into our understanding of microbial diversity and enable researchers to map phenotypes to genomes....Tiny clue reveals new path toward heart disease
...ious study, the researchers had scanned the entire genome -- the body's genetic blueprint -- of a group of families in which at least two siblings had early onset coronary artery disease, looking for regions of "linkage" where DNA variations appeared to be inherited along with the disease. They found just s...AACR's Sixth Annual Landon Awards recognize Richard Kolodner, Douglas Lowy and John Schiller
...es and the interactions between them that keep the genome stable, and he has continued to make fundamental contributions to this field through the combination of genetics and biochemistry. "Richard Kolodner has played a seminal role in our understanding of cancer genetics and pioneered many of the techniq...Mitochondrial genes move to the nucleus -- but it's not for the sex
... most obvious benefit of being part of the nuclear genome is recombination, after all, but little recombination takes place in self-pollinating species. So what, exactly, might be luring mitochondrial genes to the nucleus? "We're not quite sure why yet, but we've hypothesized that successful mitochondria...Story tips from the Department of Energy's Oak Ridge National Laboratory, March 2007
...nts a giant step in this area and illustrates that genome sequencing can deliver much-needed knowledge when clever computational approaches are applied to decode genomic information. In addition to identifying a new flexible signaling portion of the protein, Zhulin and Alexander found that changes in the si...Gene hunters, patent prospectors leave indigenous communities in Pacific feeling besieged, betrayed
...ntific proposal to patent and license the Hawaiian genome as the intellectual property of the Hawaiian people was also rejected even though it might be worth hundreds of millions of dollars. Roche Pharmaceuticals paid US $200 million for the rights to the Icelandic genome. Cultural leaders of the Kanaka Mao...New mathematical model to add rigor to studies of disease genetics and evolution
... hotspots has been fueled partly by the promise of genome association studies, which aim to locate the chrom... most recombination occurs in small regions of the genome called hotspots. As scientists have explored details of this process, it's become clear that the maj...Tiny, spontaneous gene mutations may boost autism risk
...e results suggest that many different sites in the genome likely contribute to autism. "Failure to develop social skills and repetitive and obsessive behavior may in fact be the consequence of a reaction to many different cognitive impairments," note the researchers. The new study is part of a growing ...DOE JGI releases enhanced Genome Data Management System IMG 2.1 marking 2-year anniversary
...xpanding the utility of the system for comparative genome analysis. "Over two very productive years the community has adopted IMG as a mainstay genome analysis tool and have supported and contributed to the continuous growth and improvement of the sys...Researchers use poliovirus to destroy neuroblastoma tumors in mice
... a functionally important portion of the viral RNA genome called a "spacer region", with an essential regulatory gene removed from elsewhere in the viral genome. According to Jeronimo Cello, Ph.D., senior author of the Cancer Research paper and research assistant professor at Stony Brook, this engineering...