Manipulation of epigenome turns off as many genes as it turns on
...ing a chemical called trichostatin A, or TSA, that gently unravels the chromosomes, exposing genes and allowing their instructions to be read. Much to the team's surprise, both chemical agents -- one methyl-based and one chromosome-based -- created similar patterns of changes in gene expression in th...Bug's-eye-view of urinary tract reveals E.coli infection genes
... Snyder pressed on the back of the mouse's neck or gently massaged its bladder to stimulate urination. It took about 45 minutes for Snyder and Virginia Lockatell, a technician and co-author on the study, to extract a precious drop of urine from each of the 40 mice in the study. Eight hours of mouse massage...Fussy Baby Network answers cries for help in community
... we listen, observe with the parent, and at times, gently coach. The best moment is often when the parents calm the baby, and realize they can do this." Sometimes it takes only one visit for parents to feel more comfortable and confident with their baby. But the specialists can work with the fam...Efforts to clone primates move forward
...addition to replicating the South Korean method of gently squeezing out the egg's nucleus rather than the traditional practice of removing genetic material with a vacuum needle, Pittsburgh researchers performed nuclear transfer with eggs that had not yet achieved full maturity. Cells prepare to divide by mo...Brain 'avalanches' may help store memories
...hemicals to defective networks of rat brain cells, gently easing them into a state where avalanches occur. These chemicals suggest treatments that might someday improve information storage in people with memory problems."...Human cells filmed instantly messaging for first time
... Irvine, attached small, sticky beads to cells and gently tugged the beads to and fro with laser power acting as invisible "tweezers." As the laser tweezers moved the beads in one direction, a video camera attached to a specially equipped microscope recorded the dynamic movement of biochemical signals in th...Ophthalmologists implant five patients with artificial silicon retina microchip
... the ASR, insert air into the middle of the eye to gently push the retina back down over the device, and close the incisions. Over a period of 1 week the air bubble is resorbed and replaced by fluids created within the eye. According to Chow, "The use of the subretinal space to hold a device that artificial...Georgia Tech develops mass spectrometry device that analyzes proteins faster and at a lower cost
...can potentially analyze proteins much faster, more gently and at a lower cost. "The device has the potential to completely change the landscape of this field," said Andrei Fedorov, an associate professor in the Woodruff School of Mechanical Engineering at Georgia Tech who leads the project. Fedorov's collab...Breakthrough: Scientists create world's tiniest organic particles
...onal materials into whatever particles we want and gently wash them off the molds with buffer solutions into vials or other containers to concentrate them. Then they can be injected." DeSimone, his colleagues, UNC and others have formed a new company, Liquidia Technologies Inc., with $2.5 million in angel f...The making and breaking of microtubules
...rmal microtubules, suggesting that the ribbons and gently curved sheets correspond to the polymerizing protofilaments at the end of a growing microtubule. Making contacts: In 1998, when she was a postdoctoral fellow in the laboratory of Kenneth Downing, a senior scientist in Berkeley Lab's Life Sciences...Russian River coho recovery project seeing first hopeful signs of success
...small schools of silvery adult coho swim against a gently swirling current until they're ready to be harvested for eggs and milt during December. "The circular tanks provide more depth and a greater volume of water for each fish," Conrad said. "The circular flow pattern creates superior rearing conditions t...GROWing the next generation of water recycling plants
...e troughs are rows of specially chosen plants that gently cleanse the grey water. Trickling through the GROW framework, the plants' roots naturally take up the dissolved pollutants, leaving 'green water'. Green water is not drinkable and will be dyed with a vegetable colour to signify this, but it can be us...Learning about sex from an elegant worm
...ery chromosome, one from each parent. Sex involves gently scrambling the genetic material of the chromosomes to produce variations within each species, creating individuals variously equipped to meet life's challenges. The secret of sex is meiosis, a specialized kind of cell division in which a cell replica...Protein 'nanosprings' most resilient found in nature
...hing one end of the molecules to a glass slide and gently pulling at the other end with the AFM cantilever. "After thousands of stretches, a pattern emerged," Marszalek said. "The molecule exhibited linear elasticity--a property that had never been seen in any other protein." The ankyrin repeats act like li...Nano probe may open new window into cell behavior
...ronment." The SMS probe offers the capability to gently pull biomolecules (proteins, metabolites, peptides) precisely at a specific point on the cell/tissue surface, ionize these biomolecules and produce "dry" ions suitable for analysis and then transport those ions to the mass spectrometer (an instrument...Tiny 'housekeeper' crabs help prevent coral death in South Pacific
...ntists showed the importance of trapeziid crabs by gently removing crabs from sections of the two species of branching corals on a coastal reef. This resulted in 50 to 80 percent of those corals dying in less than a month. By contrast, all corals with crabs survived. The nature of this common symbiotic rela...'Nanorust' cleans arsenic from drinking water
...engineering. "So, once the hand-held magnets start gently pulling on a few nanoparticles and get things going, the nanoparticles effectively work together to pull themselves out of the water." Colvin said, "It's yet another example of the unique sorts of interactions we see at the nanoscale." Because ir...How movement lubricates bone joints
Taking a cue from machines that gently flex patients knees to help them recover faster from joint surgery, bioengineering researchers at UC San Diego have shown that sliding forces applied to cartilage surfaces prompt cells in that tissue to produce molecules that lubricate and protect jo...News tips from the Journal of Neuroscience
...stic processing in Japanese infants. Subjects were gently fitted with headgear containing near-infrared laser emission and detection probe arrays over the lateral auditory areas. Absorption of light by hemoglobin was used to estimate blood flow changes, providing a spatial resolution of 23 cm. NIRS measures......are roughly adjacent to the eyelashes. Researchers gently pressed the volunteers' lower eyelids and collected droplets of meibum in tiny glass tubes. The researchers examined the meibum samples in the laboratory. They used a technique called electrospray mass spectrometry to differentiate between the diff...