Tag: "germ" at biology news
Wistar study demonstrates heritability of non-genomic information
...y molecules associated with DNA are removed in the germ
line cells, reset to a baseline state. Based on the current study, as well as other research conducted over the last few years, this does not appear to be entirely true. These recent observations necessarily recall the theories of 19th Century scient...
Growth factors confer immortality to sperm-generating stem cells
...imilar to embryonic stem cells. Whereas the female germ
cell, the egg, stops dividing before birth, the sp...ing to Brinster, it is possible to modify the male germ
line between generations by manipulating the spermatogonial stem cells in culture. "If each parent...
Sperm enzyme is essential for male fertility, study shows
...n the glycolytic pathway that is expressed only in germ
cells very late in the process of sperm production. GAPDS is tightly bound to a structural element that extends along most of the length of the sperm tail. The study team used gene targeting, or gene knockout technology, to produce mice that could no...
Highlights of January 2005 issue of Biology of Reproduction
...ded and then injected into seminiferous tubules of germ
cell-free mutant mice. After mating, these mice produced offspring that not only expressed the introduced EGFP construct but also passed it on to their offspring and subsequent generations. This groundbreaking work sets the stage for further germline...
Protein delivers selenium for normal sperm development
...als delivers the dietary micronutrient selenium to germ
cells, enabling these cells to develop into normal sperm. Previously, the function of this protein, selenoprotein P, was unknown, although it was believed to play a role as an antioxidant and to transport selenium throughout the body. Dietary seleniu...
New factor affects fertility
...ile is related to the progressive loss of maturing germ
cells in the testis." The animals lack sperm becau...n the adult," said Richards. "The proliferation of germ
cells is essential for fertility." She said further study may indicate whether the loss of TAF4b al...
VUMC researchers find drug-resistant bacteria MRSA a growing threat
...t of the skin infections due to the staphylococcus germ
were due to MRSA, an organism that can produce a v... MRSA who are healthy, but we are also seeing this germ
cause infections. What we are trying to understand is why some children go on to develop a serious ...
Of mice and men's (and women's) contraceptives
...any proteins are expressed in both male and female germ
lines that are specific only to the germ
line," says Hecht. Germ line refers to the group of cells that give rise to either sperm or eggs in ...
Researchers find first gene for inherited testicular cancer in mice
...y adversely affect essential aspects of primordial germ
cell biology, and the authors explain that the wor...understanding of the genetic control of testicular germ
cell tumors. "Dead end is the earliest acting genetic defect that leads to these tumors," said Josep...
$10 million gift establishes Helen L. & Martin S. Kimmel Center for Stem Cell Biology
...er. She is widely known for her pioneering work on germ
cells, which give rise to egg and sperm, during ea...embryo. By studying aberrant development of mutant germ
cell lines in the fruit fly, her research has laid the foundation for understanding the potential ca...
'Jumping genes' contribute to the uniqueness of individual brains
...nstrated mobility convincingly in cells other than germ
line cells," says Gage. Apart from their activity... and astrocytes, were unaffected. At least in the germ
line, copies of L1s appear to plug themselves more or less randomly into the genome of their host ce...
JCI table of contents, July 1, 2005
...erm before treatment commences. However, as mature germ
cells do not develop until the onset of puberty, c...hniques. Although the transplantation of one's own germ
cells after chemotherapy holds promise for restoring fertility, a major hurdle has been the risk of ...
Human embryonic stem cells have the potential to develop into eggs and sperm in the laboratory
...ociated with obtaining human samples of primordial germ
cells (PGCs), which are the ancestral cells that e... "Investigating the mechanisms of human primordial germ
cell and gamete development is important for understanding the causes of infertility and the potenti...
Self-correcting embryos could be an ethically acceptable source of embryonic stem cells
...he survival of embryonic stem cells and primordial germ
cells1." Good quality, normal embryonic stem cells were obtained initially from one of the normalised cultures, and more are being developed. So far no stem cells from completely abnormal embryos have been developed. Although the mechanism by which t...
Elderly mice yield clues to the process of growing old
...ss, loss of immune cells, anemia, and loss of male germ
cells that lead to reduced sperm production and infertility. Intriguingly, the mice develop symptoms of old age, notably gray hair and hair loss, more commonly seen in humans than mice. Prolla suggests that new studies of mice engineered to have fe...
DFG presents the 2005 MAK and BAT value lists
...es are classified according to their carcinogenic, germ
cell mutagenic, reproduction-endangering, sensitising, and skin-absorptive effect. Compared to the previous year, there were 70 changes and new entries. Changes to the 2004 list are marked with an asterisk (*). In addition, the procedure has also be...
Bone marrow may be source of new egg-cell generation in adult mammals
...e surface of mouse ovaries that resembled immature germ
cells, which are the source of the oocytes that de...tion, a molecule known to be a marker of embryonic germ
cells was found only in the core of the adult ovary, which is well supplied with blood vessels but c...
Stem cells in bone marrow replenish mouse ovaries
... help of several genetic markers that are found in germ
cells, the master cells that eventually give rise ...perm, the team shows evidence for the existence of germ
cell progenitors, putative stem cells, in mouse bone marrow and blood. In addition, the researchers ...
Studies reveal how plague disables immune system, and how to exploit the process to make a vaccine
... by the bites of infected fleas, which acquire the germ
from infected rodents. In the mid-14th century, the plague swept through Europe killing nearly one-third of the population. It returned with a slightly reduced death count about once a generation for centuries. Although far less common now, the pla...
Immune system's distress signal tells bacteria when to strike back
...ree percent of healthy people. In the bowel this germ
is usually harmless, but it can turn deadly, causing gut-derived sepsis. It is also a frequent cause of infections after major surgery. Physicians have theorized, said Alverdy, that germs such as Pseudomonas are always "probing for a weakness in t...
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