Harmful chemicals may reprogram gene response to estrogen
...f gene-environment interaction that determines who gets cancer and who doesn't." According to Walker, the increase in frequency and size of the uterine tumors is due to DES' ability to influence estrogen, a female hormone that is involved in promoting the growth of tumors by regulating the activity of key...Cancer survivors may be at higher risk for cognitive dysfunction
...s suggests that possibly the cognitive dysfunction gets worseover time with increased survival duration," Heflin said. The comparison with cancer-free twins means that the increaseddysfunction cannot be attributed to the normal aging process. The researchers also found a doubled risk of dementia in thesur...Washington State University study points to role of toxins in inherited disease
...clining in frequency as the mutated form of a gene gets passed to some but not all of an animal's offspring. The current study shows the potential impact of so-called epigenetic changes. Epigenetic inheritance refers to the transmission from parent to offspring of biological information that is not encod...New advances may slow tumor growth in pancreatic cancer
...s own poison, but every time he stings himself, he gets bigger and more powerful. "Now that we know how Smad7 is able to inactivate TGF-beta growth suppressive effects by preventing RB from functioning properly, we can focus our research on the RB protein," said Korc. They hope to find a way to disrupt...Lance Armstrong through a physiological lens: hard training boosts muscle power 8%
...h cycling stroke," it noted. As body matures, it gets "smarter" Coyle said increased muscle efficiency means that "for the same amount of cardiovascular and lung stress Armstrong is producing 8% more power, and yet producing less heat. These results have shown us how to improve already highly trained a......g it from decay. A dentist can tell when a patient gets cavities from drinking acidic beverages, such as soft drinks, since the decayed areas are often darker in color and takes up more space on the tooth. The cavities also often appear near the gumline. "Enjoying an occasional soft drink in moderation w...Parasite whips up ideas for bowel cancer treatments
...a) is a 3cm-to-5cm-long nematode or roundworm that gets its name from its whip-like shape. Once inside their host, adult worms produce eggs that are passed in the faeces and mature in the soil. If the eggs are ingested, they hatch in the large intestine where they can cause trichuriasis, a disease most co...Insects develop resistance to engineered crops
...ce to a single toxin," said Shelton. "If an insect gets a jump on one toxin, then it becomes more rapidly resistant to that same toxin in a dual-gene plant. And when one line of defense starts to fail, it puts more pressure on the second toxin in a pyramided plant to control the insect," Shelton added. Wh...Purdue scientists may have found key to halting spinal cord damage
...," Shi said. "After the initial shock, it actually gets worse. Science has long been aware that some chemicals the damaged cells release are part of the problem, but no one has ever been sure which chemicals are responsible." When a spine is damaged, the change in its ability to function follows a well-de...Scripps scientists identify target of an immune suppression molecule called CD22itself
...s. Once the dye pack is out of the bank's walls it gets activated. Then it explodes and covers the rest of the stolen bills in the sack with a telltale fluorescent dye. Similarly, B cells, once they are alerted to the presence of some pathogen in the body, will become active, proliferate, and release gob...Shark attack worries? Driving to the beach is more deadly
...rplane trips are safe, but when a crash occurs, it gets big headlines. If you use some good common sense in the water, you should be fine."...Enzyme affects hypertension by controlling salt levels in body
...ling blood pressure by controlling how much sodium gets reabsorbed back into the kidney and the blood," sa... sodium channel critically governs how much sodium gets reabsorbed." Normally, the kidney filters and reabsorbs about 99 percent of sodium from the blood an...UIC researchers show protein routes messages in nerve cells
...t to ensure that only the correct type of receptor gets attached. The work by the researchers also identifies the cytoskeleton proteins to which the receptors are tied: actin. "Many researchers have identified proteins that interact with glutamate receptors, but there's never previously been a link found ...Bitter or sweet? The same taste bud can tell the difference
...K," he said. "But this would ensure that the brain gets a clear message of what kind of taste is on the to...ime inhibit the sweet taste, so the bitter message gets to the brain." Although the researchers did not examine how either taste affected individual cells (...Scientists discover more about how cancer cells form and grow
...nd on the surface of tumor cells, then perhaps HGF gets jagged1 levels to increase, and that prompts a con...er this contact stimulates angiogenesis, the tumor gets nutrition and grows faster, Wang explained. Conversely, Wang hopes that blocking the signaling pathw...Corn fungus is nature's master blaster
...ential range to drag. And the optimum launch angle gets lower. In physics class, people are taught that the best angle is forty-five degrees, but when drag is bad, the angle needs to be lower -- you want to achieve some distance while you still have decent speed. Altitude no longer gives much advantage. T...Extravagant but worthless gifts help a guy get the girl
... by a gold-digger who intends to dump him once she gets the gift. By modelling courtship as a sequential game, they show that an extravagant gift, which is costly to the man but worthless to the woman, may solve the problem. A costly gift signals the man has long-term intentions but by being worthless t...Random gene expression may drive HIV into hiding
...ring. But the new results show that "any cell that gets infected can go down one of two paths," Weinberger said. Weinberger now is a postdoctoral fellow at Princeton University. Inspired by work that Arkin had done in the 1990s, showing that random fluctuations in viral gene expression can influence late...Chemical link indicated between drinking and certain cancers
...ed carcinogen, acetaldehyde (AA). Then the picture gets hazier. AA is known to react with 2'-deoxyguanosine (dG)--one of the chemical components of DNA--however, the main product does not appear to be mutagenic in mammals. It also is known that AA can react with DNA to produce a known mutagen (Cr-PdG. als...... lot of sizes of those DNA bands, but a child only gets one set from the mother and one from the father," Ingram noted. These markers are used in paternity cases for humans, she said. She looked for changes in the processes and patterns of this strand in mole-rats, she said. "The current methods of analys...