Abnormal fat metabolism underlies heart problems in diabetic patients
...iabetic hearts run mostly on fats for fuel because glucose isn't readily available to them," says Richard Gross, M.D., Ph.D., director of the Division of Bioorganic Chemistry and Molecular Pharmacology and professor of medicine, of chemistry and of molecular biology and pharmacology. "Unfortunately, this cha...Scientists show that mitochondrial DNA variants are linked to risk factors for type 2 diabetes
...sm and storage. One rat strain exhibited impaired glucose tolerance, reduced muscle glycogen synthesis, decreased skeletal muscle ATP (energy) levels, and decreased activity of an energy-producing enzyme called cytochrome c oxidase, when compared to the second rat strain. These metabolic characteristics ar...Study suggests estrogen deficiency can lead to obesity-induced high blood pressure after menopause
...ptin level by 70 percent increased their blood glucose level by 35 percent increased RAS and renal SNS by 16 and 39 percent experienced no change in kidney function All the hormonal and metabolic effects were completely abolished with estrogen replacement. In other words, the rats whose ovaries ...Grapes, soy and kudzu blunt some menopausal side effects
...hronic studies and about 50 percent when kudzu and glucose are administered simultaneously. Conclusion These studies demonstrate that three polyphenols grape, soy and kudzu blunt hypertension, insulin resistance and cognitive decline when estrogen is not present in female rats. According to Dr. Wys...Why nectar-feeding bats need a 'power drink' to fly
...ectars that contain simple sugars such as sucrose, glucose and fructose, but which are produced in only very small amounts by flowering plants. These sugars are rapidly absorbed and digested, and by metabolising them directly rather than converting them to fat or glycogen and then using them up later the b...JCI table of contents: August 1, 2007
... inability of the neurons to respond to changes in glucose levels and not caused by impaired responses to the...is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons AUTHOR CONTACT: Dominic J. Withers University College London, Lon...US Department of Defense awards $1.6 million for implantable biochip research
... measure and relay such information as lactate and glucose levels in the event of a major hemorrhage, whether on the battlefield, at home or on the highway. Anthony Guiseppi-Elie, C3B director and Dow Chemical Professor of Chemical and Biomolecular Engineering and professor of bioengineering says first res...Researchers find pathway that controls cell size and division
... All three enzymes in the pathway are sensitive to glucose levels, and the pathway is therefore well suited t...ent ring formation. UgtP responds to low levels of glucose (nutrient-poor conditions) by becoming unstable and forming what appear to be inactive aggregates. ...GI Caramba! Blue tortillas may help dieters and diabetics
... carbohydrates according to their effects on blood glucose levels. Foods with a lower GI are considered healt...loodstream. This reduces fluctuations in our blood glucose and insulin levels, helping to maintain a steady supply of energy. Low GI foods are said to have lon...New clue into how diet and exercise enhance longevity
...ite. They were more active as they aged, and their glucose metabolism resembled that of younger mice. The res... duration of insulin secretion needed to keep your glucose under control when you eat. Therefore, the brain is exposed to less insulin. Since insulin turns on ...JCI table of contents: July 19, 2007
...d liver cells. The result is an elevation in blood glucose levels. While the causes of insulin resistance are...C (aPKC), PKC-lambda, regulates insulin-stimulated glucose transport. In a study appearing online on July 19 in advance of publication in the August print issu...Researchers use new approach to predict protein function
...nolases are enzymes that catalyze the breakdown of glucose and related compounds into other molecules as needed for metabolism. The enzymes within the enolase superfamily utilize similar reaction mechanisms to one another but catalyze different reactions, complicating the task of discovering their function...Study shows cane sugar, corn sweeteners have similar effects on appetite
...use sucrose (table sugar) in beverages splits into glucose and fructose molecules, such as are present in hig...and 58 percent glucose. Sucrose also contains both glucose and fructose, bound together in a 1-to-1 ratio. However, the researchers found that for the sucrose ...New blood test might offer early warning of deep belly fat
...viduals with obesity, type 2 diabetes, or impaired glucose tolerance, and even in otherwise normal people with a strong family history of diabetes. Likewise, interventions designed to improve insulin sensitivity, such as exercise training, lifestyle modification, or gastric banding surgery also lead to a dec...Fat horses face health problems
... grain or concentrate consumption, which can alter glucose and insulin levels. Two independent body-condit...r signs of laminitis and blood was drawn to assess glucose and insulin levels as well as other hormones, cytokines, and oxidative biomarkers. A questionnaire ...Scientists identify 2 distinct Parkinson's networks
...at regulate movement. The scans they used measured glucose metabolism the brains fuel and identified areas in this motor network that showed decreased metabolic activity and some areas that had increased metabolic activity. Over time, the cognitive network became apparent. And as the disease progressed and...Double honors for diabetes researchers
...ould play a role in converting the effects of high glucose into nerve damage in diabetes. Further investigation confirmed the precise role these genes played. Dr Abbotts clinical research into the condition involved identifying the most effective testing methods for predicting foot ulceration caused by neu...Biotech breakthrough could end biodiesel's glycerin glut
... obtained using common sugar-based feedstocks like glucose and xylose," Gonzalez said. ...St. Jude study shows genes play an unexpected role in their own activation
...s ranging from learning and memory capabilities to glucose production in the liver. The on switch, a prote...REB might activate the genes for enzymes that make glucose in the liver, while activating different genes in the brain that are key to learning and forming mem...Pregnancy nausea/vomiting may indicate lower risk of breast cancer
... outcomes may emerge, such as high blood pressure, glucose intolerance and gestational diabetes, eclamptic conditions with seizures and/or toxemia, or extremely severe nausea. These pregnancy-related factors may serve as indicators of underlying biological conditions that may influence a womans lifetime...