Tag: "grafts" at biology news

Study points to new way to predict death risk from torn aorta

...l of abdominal aortic aneurysms treated with stent grafts -- and that this research and work by other resear...ther problems. And clinical trials comparing stent grafts to best medical therapy in aortic dissection have suggested similar outcomes for both, so they are n...

Engineered blood vessels function like native tissue

...m, providing a desirable alternative to the venous grafts now routinely done in patients undergoing coronary...ypass operations. Disadvantages with venous grafts include limited availability of vessels, pain and discomfort at the donor site and a high 10-year fa...

University of Pittsburgh School of Medicine researchers develop 'off-the-shelf' vascular grafts

...fting even though a significant percentage of vein grafts eventually fail. Arterial grafts are the preferred conduits because they are less prone to becoming obstructed. However, they are in ...

University of Pittsburgh researchers culture blood-forming stem cells from human fat tissue

...e cases that tumor cells contaminating bone marrow grafts are the source of recurrent malignancies after autologous transplantation, this might be a way of giving patients who need bone marrow reconstitution their own hematopoietic cells derived from a source other than their defective bone marrow, he expla...

PET/CT use expands: Effectively diagnosing graft infections

WASHINGTON, D.C.Removing infected vascular grafts in patients involves a complex surgical procedure ...ower limbs," said Israel. She said that prosthetic grafts are inserted to artificially restore and ensure blood circulation through the obstructed blood vesse...

News tips from the Journal of Neuroscience

...se that patients who fail to benefit from striatal grafts may have damage to ventral striatum or extrastriatal projections....

FSU engineering professor growing bone in a lab

...ecent students showing that tissue-engineered bone grafts are effective for correcting bone defects resultin...of bone that can be used for performing corrective grafts -- the patient's own body and human cadavers," Ma said. "Both of these have severe limitations. Ther...

FSU researcher's award will fund study into cardiovascular grafts

...hem quickly and in greater quantities. "Vascular grafts are needed by thousands of patients who undergo bypass surgery every year," said Teng Ma, an FSU associate professor of biomedical engineering who supervises Zhaos research. "Small-diameter blood vessel regeneration is especially challenging due to t...

Nanotextured implant materials: blending in, not fighting back

...ly about 30 percent of small diameter blood vessel grafts (less than 6 mm diameter) last more than five years, and up to 20 percent of stents need to be replaced because the artery walls thicken in and around them in a process known as restenosis. Drug-coated stents were introduced years ago as one way to c...

JCI table of contents: April 2, 2007

...g/article.php?id=31669 TRANSPLANTATION: Heart grafts avoid rejection Rats treated with a drug known as CD40Ig have been shown to accept heart grafts from rats that are not genetically identical. Although it is known that CD40Ig disrupts the interact...

Are scientists making progress in being able to regenerate bone tissue?

... Until recently, say the authors, the use of bone grafts from a different part of the patients own body has...ative is to use bone given by a donorbut such bone grafts from donors are less successful and there is a risk of transmitting viruses from the donor to the re...

Neuronal differentiation of human neural stem cell grafts in adult rat spinal cord

Neuronal differentiation of human neural stem cell grafts in adult rat spinal cord Human neural stem cell grafts can show neuronal differentiation in the normal and injured spinal cord of adult rats. Researchers f...

Grafts against cancer

... blood T-cell grafts. Peripheral blood stem-cell grafts from immunologically-matched donors are still the best way to treat or cure patients with certain leukemias and lymphomas. In Canada alone, 10 000 people have benefited from this therapy. However, this type of graft is risky because of a major potent...

Genetically altered cells may help artificial skin fight infection

...bined with a spongy layer of collagen to make skin grafts that are reattached to the burn wound. "Cultured...y to infection," says Supp. "Because cultured skin grafts aren't connected to the circulatory system at the time of grafting, they aren't immediately exposed ...

MIT creates 3-D scaffold for growing stem cells

...issues used in regenerative medicine, such as skin grafts or neurons to replace brain cells lost to injury or disease. The scaffold itself can be transplanted directly into the body with no ill effects. "The time has come to move on from two-dimensional dishes to culture systems that better represent the ...

Stem cells found in adult hair follicles may provide alternative to embryonic stem cells

...edical engineering at Marquette University, if the grafts lead to an improvement of spinal reflexes in the injured spinal cord of mice. Dr. Sieber-Blum points out that the cells may also be useful to treat Parkinson's disease, multiple sclerosis, Hirschsprung's disease, stroke, peripheral neuropathies and ...

How movement lubricates bone joints

...ts. A challenge for us is to create large tissue grafts for transplantation, said Sah. We are systematically addressing the technical challenges to maintain and grow healthy fragments of bone and cartilage in the laboratory and now we can use natures self-regulating system, whereby application of shear fo...

Weather forecasting technique wins top prize in 2006 Collegiate Inventors Competition

...e small bioengineered blood vessels. Knowing that grafts from a patient's body and synthetic grafts can have their limitations, the team experimented with a new kind of graft. Using a polymer, they cr...

News tips from the Journal of Neuroscience

...stumbling block to regeneration. They transplanted grafts of syngeneic marrow stromal cells overexpressing NT-3 into dorsal column lesions in the adult rat spinal cord; this fiber tract carries ascending sensory axons. The authors then injected lentiviral vectors expressing NT-3 at sites rostral to the graf...

ACS News Service Weekly PressPac -- Sept. 13, 2006

...may provide superior performance over conventional grafts that are used for bypass surgery, says study leader Kyle Kurpinkski, a doctoral candidate in the University's Department of Bioengineering. ARTICLE #3 EMBARGOED FOR Wednesday, Sept. 13, 1:00 p.m., EDT CONTACT: Kyle Kurpinski University of Califo...

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(Date:5/24/2013)... Modulating the immune system to combat metastatic cancer ... and destruction by the immune system. Stimulation of the ... there are many factors that cause the immune system ... cells that function to suppress the immune system response. ... Investigation , researchers led by Ronald Levy at Stanford ...
(Date:5/24/2013)... non-coding RNAs are small molecules that help control ... they have emerged as disease biomarkers. miRNA profiles ... cancers of unknown primary origin, determine prognosis, monitor ... tractable, diagnostic methods for monitoring miRNA expression in ... issue of the Journal of Clinical Investigation ...
(Date:5/24/2013)... Alzheimer,s disease, scientists have focused among other factors ... all, it is the accumulation of A-beta that causes the ... for the formation of A-beta is APP. Alessia Soldano and ... function of APPL the fruit-fly version of APP ... Soldano (VIB/KU Leuven): "We have discovered that APPL ensures that ...
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