Analysis of breast-cancer gene role offers promising target
... the breast-cancer prognostic factors that has the greatest level of evidence. "All the work has been on the protein and enzymatic activity and not amplification of the gene, which is a very reliable and easy-to-use diagnostic test called FISH," said Dr. Tripathy. "The other important finding is that HER-2 ...Yale journal identifies products that cause greatest environmental damage
...h identifying the types of products that cause the greatest environmental damage is the focus of a special issue of Yale's Journal of Industrial Ecology. Seventy percent to 80 percent of the total environmental impact is from automobiles, air transport, food (meat and dairy, chief among them), home and rel...Data show treatment with Remicade reduced hospitalizations for ulcerative colitis patients by half
...ls who require inpatient hospitalizations have the greatest overall healthcare costs. In fact, inpatient hospitalizations account for approximately 42 percent of UC patients' total healthcare costs annually. Reduction of hospitalizations was sustained through one year in ACT I with approximately 50 percent...Researchers report initial success in promising approach to prevent tooth decay
...nic care," said Shi. "They represent three of the greatest public-health discoveries of the 20th century, but each has its limitations in the mouth. Take vaccination. We can generate antibodies in the blood against S. mutans. But in the mouth, where S. mutans lives and our innate immunity is much weaker, ...ACS News Service Weekly PressPac -- October 11, 2006
...BPs and 50 unregulated DBPs regarded as posing the greatest health risks. Their report is scheduled for the Dec. 1 issue of the semi-monthly ACS journal, Environmental Science & Technology. Some treatment plants have switched from chlorine to alternative disinfectants such as ozone, chlorine dioxide and chl...Mass vaccination unnecessary in the event of a large bioterrorist US smallpox attack
...ssifies it as a "Category A" agent, presenting the greatest potential threat for harming public health if developed and used as a bioterrorist agent. Smallpox is caused by the variola virus, which emerged thousands of years ago. Variola major, the most common form of the virus, is divided into four subcatego...Rescuing injured hearts by enhancing regeneration
...nase inhibitor. Rats receiving both agents had the greatest improvements in both cell proliferation and heart function. The findings suggest that getting cardiomyocytes to replicate is not enough to rescue heart function, but that angiogenesis is also needed, Engel says. "Regeneration is not just making m...Uncovering DNA's 'sweet' secret
...le and its sister molecule, RNA,remains one of the greatest - and potentially unsolvable - scientificmysteries. But Vanderbilt biochemist Martin Egli, Ph.D., isn't content to simplystudy these molecules as they are. He wants to know why they are the waythey are. "These molecules are the result of evolution,...Predicting species abundance in the face of habitat loss
Habitat loss poses the greatest threat to the survival of a species, and often precipitates the demise of top predators and wide-ranging animals, like the Siberian tiger and the orangutan. Any hope of recovering such critically endangered species depends on understanding what drive...Groundbreaking study by Field Museum scientists explains mane variation in lions
...l east Africa was chosen for the study because the greatest range of mane variation occurs there. In fact, both maximum and minimum mane conditions have been documented there historically, and continue to exist today, making it an ideal region for addressing the questions posed by the authors (see Velizar Si...What animals can tell us about hemorrhage, organ transplants and aging
... the loss of blood flow (ischemia) that causes the greatest damage to the organs and tissues, explained Andrews. Instead, the greatest damage occurs when the blood flow is restored (reperfusion). Hibernating animals have significantly ...Skeletal microdamage stable after first year
...se results suggest that microcrack accumulation is greatest during the early course of alendronate treatment. This is an encouraging sign for long-term safety of these drugs. ASBMR President-Elect Steve Goldring, M.D., notes: "These findings have important clinical implications with respect to the long-term...Mouse strain with gene stutter will help leukemia research
... what causes leukemia in people, predict who is at greatest risk and prevent leukemia from ever developing in those patients." Genes store information for a protein. Mutations can alter the protein, perhaps making it function differently. In this case, the duplication within the MLL gene contributes to an a...Planning ahead: Having the healthiest baby possible
... of the lead article of the Supplement, said, "The greatest opportunities for improving the health of mothers and babies lie in prevention strategies implemented before conception." Dr. Hani Atrash, co-editor of the Supplement and associate director for program development at the Centers for Disease Control ...Preeclampsia, fetal development problems may be linked to low levels of hormone
...nsion and diabetes. According to Caron, one of the greatest increases occurs during the course of a normal pregnancy, when the placenta secretes adrenomedullin levels reach four to five times higher than normal by the third trimester before rapidly returning to pre-pregnancy values after delivery. But in w...Define 'precautionary principle' to avoid clashes over biotechnology under World Trade rules
...principle may be its strength, but also one of its greatest weaknesses. Several WTO Members have noted in the Committee on Trade and Environment (CTE) that the difficulty of further integrating precaution in the WTO lies in the lack of an internationally-agreed definition of the precautionary principle." Sa...Raloxifene reduces breast cancer risk in postmenopausal women at all risk levels
...chers say they cannot explain why protection seems greatest in women who may be genetically predisposed to develop the disease. "We don't know what to make of this observation," said Marc E. Lippman, M.D., professor in the Department of Internal Medicine at the University of Michigan and the study's lead au...Craig Mello named winner of The Dr. Paul Janssen Award for Biomedical Research
... extend the legacy of Dr. Paul Janssen, one of the greatest scientific innovators of our time," said Dr. Mello. "I am also very thankful to the Selection Committee for giving me this Award and to be considered alongside so many great scientists." RNA interference is a biological process where double-stranded ...Using nature's most primitive anti-viral defense system to find new approaches to cancer research
... and his team are charged with tackling one of the greatest scientific challenges of all."...Compounds in cranberry juice show promise as alternatives to antibiotics
...uice that has not been highly diluted may have the greatest health effects. The new results build on previously published work, in which Camesano and her team showed that cranberry juice causes tiny tendrils (known as fimbriae) on the surface of the type of E. coli bacteria responsible for the most serious t...