Tag: "gut" at biology news

Bugs in the gut could play key role in understanding human disease and drug toxicity

Understanding how microbes in the gut interact with the body could lead scientists and d...hnology , researchers describe how microbes in the gut form the second largest metabolic 'organ' in the body and play a key role in disease processes along...

Gut microbes can open gates in fat cells

...04 -- The microorganisms that normally live in the gut can increase body fat, say researchers at Washingt...y School of Medicine in St. Louis. They found that gut microbes can open the "gates" fat uses to enter the body's fat cells. Using a two-pronged strategy, ...

In a tiny squid, bacterial toxin governs organ development

... with their human hosts. Many of those live in the gut and help with critical processes, such as digestion and the provision of certain vitamins. Also, the bacterial partners that normally occur with the healthy human are critical for the development of the immune system. There is evidence, for example, ...

Lyme disease receptor identified in tick guts

... ticks. "We identified a receptor inside the tick gut that the spirochete bacteria use to colonize or invade ticks," said principal investigator Erol Fikrig, M.D., professor of internal medicine/rheumatology and in the Section of Microbial Pathogenesis, and Department of Epidemiology and Public Health a...

Scientists first to grow common cause of food poisoning in the lab

...ndritic cells just beneath the lining of the human gut that are providing the gateway the virus needs to cause disease," Virgin says. To grow the virus in the lab, researchers took dendritic cells and macrophages from mice with defective innate immune systems and exposed them to the virus. "The virus g...

JCI table of contents, December 1 2004

...733.pdf Understanding how prostaglandin prevents gut injury during radiation therapy People undergoing...effective for protection against radiation-induced gut injury in humans. TITLE: Prostaglandin E2 reduces radiation-induced epithelial apoptosis through a ...

Healthy mix of GI tract microbes are key to preventing allergies and asthma

... U-M Medical School. "Change the microflora in the gut and you upset the immune system's balance between ...five-day course of antibiotics, which killed their gut bacteria, followed by a single oral introduction of the yeast Candida albicans. Increased growth of ...

Opposing fat metabolism pathways triggered by a single gene

...imal displayed numerous gross abnormalities in the gut and gonad. This was accompanied by unusually high fat content in the larvae. They further showed that deletion of nhr-49 changed expression of 13 genes related to fat and glucose metabolism, with the most dramatic effects occurring within two meta...

Stockpile bird flu vaccine now

...only one shot of a specific pandemic vaccine. "My gut feeling is that if you're primed with H5, you'll respond better to the flu or to the real vaccine," says Tony Colegate of Chiron Vaccines in Liverpool, UK, who heads an international industry task force on pandemic flu. Such evidence has persuaded th...

Genome of deadly amoeba shows surprising complexity, evidence of lateral gene transfer

...biology between the parasitic amoeba and anaerobic gut bacteria. The E. histolytica genome sequence...teria and shares a close relationship in the human gut with its bacterial neighbors. Because the parasite uses the same methods to kill bacteria as it uses...

Highlights of chemical society national meeting in San Diego, March 13-17

...n the chemical signals produced by bacteria in the gut when the bacteria reach a certain critical level, the new test could allow patients to predict disease flare-ups and reduce the severity of their disease using drug intervention. A home-based version of the test is anticipated, they say. ( ANYL 96 ,...

Highly adaptable genome in gut bacterium key to intestinal health

...r. 24, 2005 -- A bacterium that lives in the human gut adaptively shifts more than a quarter of its genes...the journal Science. "Bacterial cells in the human gut number close to 100 trillion," says Jeffrey Gordon, M.D., director of the Center for Genome Sciences...

Liverpool scientists uncover how E.coli became lethal

Twenty-three years ago a harmless gut bacterium called E. coli developed the ability to kill people through food poisoning, bloody diarrhoea and kidney failure. Normally E. coli bacteria live in the intestine and don't pose any danger, but some varieties can cause fatal food poisoni...

Why do amyloid diseases strike different tissues?

... and still others cause the fibrils to form in the gut or in the brain. In the latest issue of the journa... in modulating neurotransmission. And cells in the gut secrete proteins designed to digest proteins. The export machinery that drives this secretion is lo...

Breakthrough in stem cell research

...ch are derived from the layer which also forms the gut and liver are the holy grail for diabetes researchers," said Dr Sidhu. "That's because they are destroyed in type-1 diabetes, which affects at least 100,000 people in Australia. So far there is no cure for it. "Human embryonic stem cell research off...

Researchers identify protein crucial for survival of Lyme-disease bacterium

...cterium Borrelia burgdorfei (Bb) to survive in the gut of its tick host and may offer a potential new target for agents aimed at eradicating Lyme disease. Results of the multisite study are currently online and will appear in an upcoming issue of the Proceedings of the National Academy of Sciences. The...

A frog's life is food for thought

...t the effects of prolonged food deprivation on the gut of animals that go without food for long periods. ...gularly. "I compared the various aspects of their gut biology and physiology," she said. "We put animals into aestivation and woke them up and fed them t...

Researchers discover mechanism for multiplying adult stem cells

...gene on, the mice immediately formed tumors in the gut and in the skin where the gene was active. When he switched the gene off, the tumors subsided, demonstrating that the process is reversible. Discovering that simply flipping a single gene on and off has such an immediate effect on a tumor was unexpe...

Killer dinosaurs turned vegetarian

...eeth to leaf-shredding teeth, the expansion of the gut to a size needed to ferment plants, and the early ...tives. Its pelvis was broader, indicating a larger gut to digest plant material, which is more difficult to process than meat. Its lower legs were stubby, ...

DOE JGI announces 2006 Community Sequencing Program portfolio

...tly involved in hydrogen production in the termite gut may one day make biological production of this alternative energy source a viable option. DOE JGI also will be casting deep into the aquatic gene pool--sequencing genes from two species of catfish, the Channel catfish (Ictalurus punctatus) and the bl...

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(Date:10/18/2014)... stress and stress-related psychiatric disorders are associated ... the molecular mechanisms underlying this relation are ... the development of targeted preventive strategies and ... diseases. This work is presented at the ... Now an international group of researchers from ...
(Date:10/18/2014)... In a sample of patients with undiagnosed, suspected genetic ... associated with a higher molecular diagnostic yield than traditional ... JAMA . The study is being released to ... meeting. , Exome sequencing, which sequences the protein­coding region ... genetic material present in a cell or organism), has ...
(Date:10/17/2014)... available in German . ... every day in order to reproduce? And why are there ... of the latest issue of the research journal Molecular ... biologist Steven Ramm from Bielefeld University Bielefeld has compiled this ... unusual for a female to copulate with several males in ...
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