Parasite whips up ideas for bowel cancer treatments
...tems. "The body naturally renews the lining of the gut every few days as cells rise to the surface and ar...s its cells allowing it to burrow further into the gut wall. "We were able to counteract this by speeding up the cell 'escalator' artificially but some hos...A protein in the eye may prevent immune response and protect eyes from disease
...overed two decades ago on immune cells in the eye, gut and other privileged sites, but its function has not been understood. In an attempt to understand F4/80, Stein-Streilein and her team have been following the immune cells (also known as antigen presenting cells) containing the protein. In previous s...Stolen gene allows insect virus to enter cells
... Blissard explains: one type specialized to infect gut cells, and another that spreads infection in other parts of the insect. The latter type uses F to enter cells. An ancestor of today's baculoviruses "might have just existed as a diarrheal-type virus, reproducing itself at a low level in the gut, lett...Agricultural antibiotic use contributes to 'super-bugs' in humans
...able but imperfect gastric barrier to colonize the gut - which in turn may transmit the resistant bacteria to humans. Smith and colleagues say that the transmission of antibiotic resistant bacteria from animal to human populations is difficult to measure, as it is "the product of a very high exposure r......arasites, known as oncospheres, burrow through the gut wall. They then migrate through the body and lodge...he eggs hatch in the intestine, burrow through the gut wall and travel to muscles, where they form cysticerci. The infection rarely causes symptoms in pigs...Micro-molecule plays big role in birth defects
...rfe said. "Most structures, such as the heart, the gut and the lungs, haven't even formed yet. Now we can bypass the problem of early mortality and study the structures as they develop. It's a new tool for the genetic researcher's toolbox." No more than five years ago, microRNAs were considered to be lit...JCI Table of contents August 1, 2005
...icle.php?id=25642 PHYSIOLOGY What's good for the gut is good for the gallstones Four years ago, the beta klotho gene in mice and its human homologue were identified. Beta Klotho structurally resembles Klotho, a protein whose deficiency elicits various human ageing-like phenotypes in mice. However, th...Researchers devise new technique for creating human stem cells
...into nerve cells, hair follicles, muscle cells and gut endoderm cells. And, since these cell types are derived from three different parts of the embryo, this really demonstrated the ability of these cells to give rise to a variety of different cell types." Furthermore, Eggan noted that genetic analyses o...Seaweed could make junk food healthier
...ngthen mucus, the body's natural protection of the gut wall, can slow digestion down, and can slow the uptake of nutrients in the body. Moreover, alginate is high in fibre and has been proved to be palatable and safe, and as such is already in widespread use by the food industry as a gelling agent, to re...Antibody to a naturally-occurring sugar chain in colon inhibits inflammatory bowel disease
...binds to an unusual sugar molecule residing in the gut halts the inflammation seen in Crohn's disease and other intestinal inflammations. The antibody could prove to be a promising drug target for these common chronic intestinal disorders. Professor Hudson Freeze, Ph.D., director of Burnham'...Newly discovered hormone keeps digestive acid in check
...ne with an important role in signaling between the gut and liver, Kliewer said. The results may also have important medical implications. For example, patients who can only receive nutrients intravenously often develop liver damage, he said. The new study suggests this condition may result from an excess...NHGRI's large-scale sequencing research network sets its sights on disease targets
...mes of 100 bacteria cultured from the normal human gut will be sequenced. "We ar...he development of vaccines. The human gut microbiome project represents an exciting new research area for NHGRI, which, except for the bacteri...Worms know bad food when they smell it
...then they establish an infection inside the worm's gut and they proliferate there. It's exactly like food poisoning," Bargmann explained. If the worm has ingested enough of the bacteria, it can die quickly, but milder cases allow the worm to live for several days and head off in search of better food. S...Student scientists create living bacterial photographs
... found naturally in the dark confines of the human gut and wouldn't normally sense light, so the students had to engineer the unicellular machines to work as a photo-capturing surface. UCSF biophysics graduate student Anselm Levskaya and his adviser, Dr. Chris Voigt, first engineered the bacteria to sen...Regenerating worms help elucidate stem cell biology
...enishes itself, wounds heal, and the lining of the gut sloughs off and is restored. Nowhere, however, is the process of regeneration more dramatic than in the freshwater flatworm planaria. Cut one of these animals in half, and a week later, two fully functional worms will have developed from the pieces. ...Similar stem cells in insect and human gut
...me stem cells controlling cell regulation in their gut as humans do. The research is important for unders...ility as well as growth and differentiation of the gut (enteroendocrine cells). In vertebrates, cells of the intestines are continually replenished by st...Study fishes out new role for prostaglandins
...p the innermost layer (endoderm), which forms the gut and associated digestive organs; the middle layer (mesoderm), which develops into muscle, bone and cardiovascular organs, and the outer layer (ectoderm), which becomes the skin and nervous system. "The body is a tube in a tube in a shell," Solnica-K...Advancing the biomedical frontier: Experimental Biology 2006
... stress, obesity, the friend/foe physiology of the gut lining with the bacteria that live there, adaptive responses to stress, lipid metabolism and liver inflammation, and the connection between mitochondrial function in skeletal muscle and disease. One symposium focuses on the physiology of high perfor...Human trial proves ricin vaccine safe, induces neutralizing antibodies; further tests planned
...food may require inducing immunity in the lung and gut by a very different formulation and vaccination schedule. Depending on how the ricin is administered as a poison, victims develop fever, nausea and abdominal pain or lung damage before dying within a few days of exposure. There is no antidote after t......ough this is exciting, the levels of donor derived gut cells are currently far too low to be used as a treatment for cystic fibrosis, an inherited disease in which the organs, especially those of the pancreas, lungs, and intestines, become clogged with thick mucus. "We hope this finding will have implica...