U of Penn researchers identify gatekeeper involved in chronic inflammatory diseases
...augmenting the abilities of IL-27 may be enough to halt inflammation. "There are many immune-mediated diseases with many different causes, but the type of cells that IL-27 inhibits are a major part of the pathway of cellular signals that lead to inflammation," said Christopher Hunter, professor in Penn V......e ability of naturally-occurring microbes that can halt the uranium's underground migration to prevent it from reaching streams used by plants, animals and people. Assembling a battery of evidence, scientists have for the first time placed the bacterial enzymes responsible for converting uranium to uran...Researchers appeal for new regulations to save coral reefs from live fish trade
...ambridge, have called for action by governments to halt the unsustainable plunder of the world's ocean resources. For decades tropical coral reefs have battled for survival against a complex array of threats including pollution, coral bleaching triggered by rising sea temperatures and over-fishing. ...Dengue virus reveals its circular secret
...o building blocks in this structure were enough to halt the replication process. "That told us that RdRp probably discriminates the viral RNA by recognizing SLA," Gamarnik said. To confirm the vital link between RdRp and SLA, the researchers allowed virus particles that couldn't replicate to evolve in ...NC State scientists characterize protein linked to neurodegenerative diseases
...his case, may provide clues to developing drugs to halt the diseases. The research appears in the July 2006 edition of Nature Structural and Molecular Biology. Calbindin-D28K is a protein that either grabs calcium from areas that have too much or serves as an on/off switch for further chemical reactio...Titans of biodiversity science call for united, authoritative voice to inform decision-makers
...ith one clear voice advise governments on steps to halt the potentially catastrophic loss of species already occurring," says Dr. Watson. "The climate change panel, the International Assessment of Agricultural Science and Technology, the Ozone Assessment Panel and other scientific collaborations today p...Possible birthplace of malignant brain tumors identified
...ed that the PDGF infusion caused the stem cells to halt their normal production of mature brain cells and launch into the abnormal proliferation pathway. Importantly, the researchers found that stopping the PDGF infusion caused a complete regression of the nodules. The researchers wrote that "these find...Dopamine drug leads to new neurons and recovery of function in rat model of Parkinson's
...h time. There are no treatments proven to slow or halt the course of PD. However, many researchers have been trying to find ways of replacing the lost neurons. One possible way to do this would be to transplant new neurons that are grown from embryonic stem cells or neural progenitor cells. However, ...Neurons grown from embryonic stem cells restore function in paralyzed rats
...." Previous studies have shown that stem cells can halt spinal motor neuron degeneration and restore function in animals with spinal cord injury or ALS. However, this study is the first to show that transplanted neurons can form functional connections with the adult mammalian nervous system, the researche...Einstein's Susan Band Horwitz, PhD wins Bristol-Myers Squibb Cancer Research Award
...unctions of microtubules, paclitaxel in effect can halt or impede uncontrolled cancer cell growth. Today, paclitaxel remains widely used in the treatment of many types of pervasive tumors, including ovarian, breast and non-small cell lung cancers. Since her groundbreaking discoveries, Dr. Horwitz has m...Scientists design potent anthrax toxin inhibitor
...n inhibitor might act synergistically to lessen or halt anthrax symptoms, notes Dr. Kane. Using the same technique of placing multiple peptides on a liposome, the researchers also created a polyvalent inhibitor of cholera toxin that functioned well in test-tube experiments. In the next phase of their rese...Georgia Tech computer program designed to halt pandemics installed in Georgia
...spread within treatment sites and possible ways to halt or minimize the spread. It will also determine how to redirect patients should one center need to be quarantined or closed to prevent further spread of a disease....Scientists discover a genetic switch that links animal growth and cancer
...lopment into a mature tree. Many animals similarly halt their development until the environment is right for growth and development." The process is the same with cells, the basic units of life. Many cells remain in a quiescent state, neither growing nor multiplying until they are triggered to do so by an...New model of p53 regulation proposed that suggests novel anticancer strategy
... researchers thought Mdm2 and Mdm4 collaborated to halt the activities of p53. As a powerful tumor suppressor, p53 turns on genes that either halt cell division, to allow time for repair of damaged DNA, or, when all rescue attempts prove futile, o...First clinical results reported for Sangamo's ZFP therapeutic
...is is important, as previous therapies designed to halt or reverse the nerve deterioration that is characteristic of this condition had dose-limiting toxicities that prevented testing at dosing proven to be effective and tolerated in animal studies. For this reason, we are looking forward to initiating a...Fish oil may help protect against retinal degenerative diseases
...o the design of novel therapeutic interventions to halt or slow disease progression."...Low dose vitamin A derivative does not prevent head and neck tumors, clinical trial finds
...ed that vitamin A derivatives called retinoids may halt or even reverse growth of head and neck tumors. A clinical trial of high doses of a retinoid called isotretinoin, widely used to treat cystic acne, in patients with HNSCC found that those receiving isotretinoin developed fewer second primary tumors, ...Media Invite: Dinner to award prize for Progress in Cancer Research
...ering hope for angiogenesis-centered treatments to halt and even reverse tumor growth." Published in 1983 in the journal Science, Harold Dvorak, M.D. and his colleagues were the first to show that tumor cells secreted VPF and that a blocking antibody to VPF could prevent the devastating edema and fluid ac...Pain killer fights breast cancer by targeting key enzyme
A painkilling medication appears to halt the production of an enzyme that is key to a commo...e, the problem is that the current inhibitor drugs halt estrogen production throughout the body, said Robert Brueggemeier, a study co-author and a professor...For the first time: Longevity modulated without disrupting life-sustaining function
...r a long life with fewer progeny and a tendency to halt larval development and enter a dormant, hibernation-like stage in which they can hang on for months but don't reproduce. Unless Smk-1 is missing, that is. Without Smk-1 to provide guiding assistance, DAF-16 is unable to slow down the aging process, ...