Random gene expression may drive HIV into hiding
...esign new and more effective treatments to slow or halt the progression of HIV infection. HIV normally replicates rapidly in the body's white blood cells, but, in some cells, the virus stops replicating and becomes dormant. Researchers have long puzzled over how HIV makes the "decision" to become latent o...Duke professor to lead $300 million NIH center for HIV vaccine research
...e comprehensive prevention strategies necessary to halt the spread of HIV in both developing and developed countries. In addition to Haynes, the CHAVI senior scientific leaders include Norman Letvin, M.D., of Harvard Medical School; Joseph Sodroski, M.D., of Harvard Medical School; George Shaw, M.D., Ph....U of MN researchers reverse memory loss in mice
...mory and improve in cognitive function if they can halt progression of the disease. The study measured the mice's spatial memory through a water maze--a pool of water with a submerged platform. The use of this maze taps into the hippocampus, an area of the brain important in Alzheimer's disease research...UCLA scientists reveal how Nipah virus infects cells
...g the cells. This will help prevent infection and halt outbreaks before they reach epidemic proportions." Since 1998, the Nipah virus has triggered disease outbreaks in Australia, Singapore, Malaysia and Bangladesh. Animals spread the virus to people, where it causes life-threatening respiratory and neu...Purdue researchers find key to rice blast fungus
WEST LAFAYETTE, Ind. - Efforts to halt a fungus that deprives about 60 million people a year of food have led Purdue University scientists to discover the molecular machinery that enables the pathogen to blast its way into rice plants. The fungus, Magnaporthe grisea, which is known as ric...Cancer related gene p53 not regulated as indicated by previous tissue culture research
...ctivate the production of other proteins that will halt cell division if the DNA damage can be repaired. ...and was stable and fully functional when needed to halt the cycle cell to repair DNA damage or to induce apoptosis. "It came as a complete surprise. We eve...Experimental vaccine protects nonhuman primates from Lassa fever
...rently there is no preventive measure available to halt the spread of Lassa fever, other than rodent control in affected areas. The disease is transmitted to humans from rodents that carry the virus. Lassa fever is common in parts of West Africa where it causes a significant amount of death and disability...New understanding of DNA repair may pave way to cancer treatments
...aks in DNA. A likely way in which ATF2 works is to halt the cell's cycle to allow repair of damaged DNA before such damage becomes permanent." Ronai and his colleagues are now determining how molecules like ATF2 can balance their dual roles. "High doses of radiation, as well as changes that take place i...Ecosystems, economic choices and human well-being
...le, but relying solely on the numbers will fail to halt biodiversity loss, the MEA asserts. "Ultimately, more biodiversity will be conserved if ethical, equitable distribution and spiritual concerns are taken into account than if only the operation of imperfect and incomplete markets is relied on," it sta...Researchers find gene that may be at root of potato blight
...ht breakout in 2003 brought potato production to a halt in Papua New Guinea , one of the few countries in the world that was previously free of the disease. Agricultural problems caused by oomycetes don't stop with P. infestans. Related Phytophthora species cause root rot in soybean plants as well as sud...To stop evolution: New way of fighting antibiotic resistance demonstrated by Scripps scientists
...e shut off as well. Doing so, he says, would put a halt to evolution -- an interesting prospect because th...n. If one could design drugs to halt the enzymes that make mutations in bacteria, this could be a way of combating the evolution of antib...Scientists discover odd-ball rodent
...os to help enact an aggressive program designed to halt illegal wildlife trade where poaching has devastated animal populations. "It was for sale on a table next to some vegetables. I knew immediately it was something I had never seen before," said Dr. Timmins. Dr Mark Robinson, working with WWF Thailan...New tool reveals secrets of migrating cells
...bly those that have made a decision on their fate, halt their wanderings and make a beeline out of the cortex to the medulla, something immature T cells can't do. The scenario they've reconstructed from the video and mathematical analysis starts with immature T cells moving out of the center of the thymus...JCI table of contents May 2, 2005
...aids in the potential design of therapies that can halt BOS. TITLE: Vascular remodeling during the pathogenesis of broncholitis obliterans syndrome: the role of CXCR2/CXCR2 ligands AUTHOR CONTACT: John Belperio University of California Los Angeles, Los Angeles, CA USA Phone: (310) 794-1999; Fax: ...Unexpected lock and key mechanism found for the assembly of tumor blood vessels
... in research that promises to lead to a new way to halt tumor growth by cutting off the tumor blood supply. The research team led by Judith Varner, Ph.D., Associate Professor of Medicine at UCSD and a member of the Rebecca and John Moores UCSD Cancer Center, made the surprising discovery that a receptor-......ponse to DNA damage, instructing a damaged cell to halt cell cycle progression and either initiate DNA repair processes or programmed cell death. While much research has focused on the identification of moleculaes that help transduce these signals throughout the cell, in their current paper, Dr. Lawrence ...Alaskan puzzles, monitoring provide insight about North Pacific salmon runs
... replace themselves in spite of an almost complete halt to harvesting, says Ray Hilborn, UW professor of aquatic and fishery sciences. "The Kvichak sounds a lot like Columbia River or Puget Sound stocks," he says. Still, 20 miles away from the Kvichak are similar lakes and rivers with record production....Biomarkers isolated from saliva successfully predict oral and breast cancer
... normal subjects. New techniques were developed to halt RNA degradation so the scientists could recover as much mRNA as possible for their samples. In all, the new techniques allowed the scientists to harvest up to 10,000 types of human mRNA from saliva, setting up a comparison test between cancer patient...Penn researchers determine structure of binding site of colon-cancer drug and its protein target
...on and colleagues determined that Erbitux works to halt cell proliferation by blocking EGFR's molecular doorway, disallowing hormones to bind and signal tumor growth. X-ray crystallography provided a snapshot of the interaction between Erbitux and the extracellular component of the cancer cell's receptors...Unchecked DNA replication drives earliest steps toward cancer
...owever, or the p53 pathway is unable to completely halt the process, further mutations will occur, leading the cell to become cancerous, with the number of mutations constantly growing. So, when p53 remains intact, it is often able to prevent cancers from developing. When it suffers damage itself, cancers...