Fever after smallpox vaccination tied to individual genetic variations
...ne smallpox vaccinations in the United States were halted in 1972, when the disease was considered eradicated in this country, but the U.S. military and other high-risk groups, including some healthcare workers, continue to get the vaccine. It is made with a live but weakened vaccinia virus that provides im...Stray penguins probably reached northern waters by fishing boat
...ith the adoption of international regulations that halted much of the trade. Since then, they said, zoos in the United States have bred penguins in captivity and managed their penguins as one large population, moving individuals from specific zoos to reduce inbreeding. It would not be easy for the birds to ...Breakthrough for treatment of fatal heart condition
...that the progression of cardiac hypertrophy can be halted by increasing one of the bodys naturally occurring proteins. This is a significant discovery because whilst the symptoms can be managed, the cause of heart hypertrophy cannot yet be treated. This research provides a first step in the search for a pos...Nexavar significantly extends overall survival by 44 percent in liver cancer patients
... School of Medicine, New York. Bayer and Onyx halted the SHARP trial in February 2007 when an independent data monitoring committee determined in a pre-scheduled analysis that the overall survival endpoint had been met. There were no significant differences in serious adverse event rates between the N...Use of wind energy in US growing, but planning and guidelines are lacking
...hadow paths avoid residences, or operations can be halted during times when troublesome flicker occurs. The report also considers beneficial and adverse economic effects on local areas -- such as effects on landowners, the regional economy, and local government revenues -- and recommends measures to anti...African carnage -- 1 year's seized ivory likely came from 23,000 elephants
... reinstate strong enforcement efforts that all but halted black-market ivory trade in the four years immediately after the ban was enacted, said Samuel Wasser, director of the UW Center for Conservation Biology. He is the lead author of a paper detailing the problem published the week of Feb. 26 in the onli......by Pfizer, and now in clinical trials) effectively halted tumor progression in BRaf(VE) mice. Interestingly, however, without pharmacological intervention, the BRaf-mutant tumors eventually stopped proliferating, and entered into a senescent state. This senescent state could be overcome by concomitant mutat...The code of codes -- Scientists discover parallel codes in genes
... during protein synthesis, the process is promptly halted before energy and resources are wasted. "Our findings open the possibility that genes can carry additional, currently unknown codes," explains Dr. Uri Alon, principal investigator on the project. "These findings point at possible selection forces ...Reversal of symptoms in an autism spectrum disorder
...they give hope that the symptoms could not only be halted from progressing, but the course of the disease itself may be able to be reversed," stated Fred Gage, Ph.D. of the Salk Institute of Biological Studies. "Dr. Bird's astonishing results usher in a new era for Rett Syndrome and other autism spectrum...Phase III trials of cellulose sulfate microbicide for HIV prevention closed
...research organization, announced today that it has halted a Phase III clinical trial of cellulose sulfate --...ultaneously, Family Health International (FHI) has halted a second Phase III cellulose sulfate trial in Nigeria. Although the FHI trial did not detect an inc...Buildup of damaged DNA in cells drives aging
...DNA damage somehow triggered hormonal changes that halted growth, while also boosting maintenance and repair. Because growth hormone levels go down as we get older, contributing to loss of muscle mass and bone density, the investigators systematically compared the gene expression pattern of their progeroi...Other highlights in the December 20 JNCI
...cancer. They found that cromolyn bound to S100P, halted the activation of RAGE, and slowed cancer cell growth and survival in cell lines. In mice, the drug slowed pancreatic tumor growth and improved the effectiveness of gemcitabine, a chemotherapy drug used to treat pancreatic cancer. "Together, these ...USGS presents a world of science at GSA in Philadelphia
...USGS, the U.S. military, and private industry have halted the migration of trichloroethylene into the Delaware River and downstream into Philadelphia. Keeping the plume contained on base has allowed research on natural substances that are showing the potential to clean up this type of spill -- to break the...UC Davis breast cancer researchers report new insights into ductal carcinoma in situ
...ssion of MIN cells towards mammary cancer could be halted in some cases. The team, led by Lawrence Young, a senior research associate in the Center for Comparative Medicine, and Jeff Gregg, an associate professor of pathology, found that the antibiotic rapamycin quickly induced apoptosis, or rapid cell deat...British cattle give TB to badgers, finds UC Davis expert
...ic of foot-and-mouth disease in Englandtemporarily halted routine TB testing of cattle, infection rates inbadgers doubled. At this time, infected cattle remained in theirherds and the researchers suggest that this allowed them to transmitthe disease to other cattle and to badgers. "Our findings helps to ex...Jumping gene could provide non-viral alternative for gene therapy
...cy comes at a price. Gene therapy trials have been halted because of major complications, including deaths. As examples, one patient died because of his immune response to an adenovirus and three children in another study developed leukemia because the virus inserted itself upstream of a cancer-causing gene...Twist on chest pain drug improves heart attack outcome
...n through each rat heart before the blood flow was halted and again during reperfusion. Results showed that pre-treatment with the derivatives TMZ-NH and TMZ-NH was most effective at protecting hearts from injury by subsequent reperfusion. TMZ alone offered some protection from tissue damage during reperf...New approach to vaccine development provides potent, long-lasting immunity
...sing this delivery approach, a single immunization halted the progression of melanoma and significantly extended survival in a mouse model. The approach makes use of an inactivated retrovirus, in this case, a modified lentiviral vector more commonly known for its ability to carry functional genes in certai...'Resonance' may explain virologic failure in STI drug therapy
...ional Institute of Allergy and Infectious Diseases halted enrollment into an international HIV/AIDS trial known as Strategies for Management of Anti-Retroviral Therapy, which compared continuous antiretroviral therapy with episodic drug treatments, after researchers determined that patients on episodic trea...DNA gene vaccine protects against harmful protein of Alzheimer's disease
...ed into muscle, Dr. Rosenberg said. That study was halted when a small percentage of participants developed inflammation of the brain and spinal cord. Injecting the gene, in contrast, caused no brain inflammation in the mice. Dr. Rosenberg said the difference was partly because in the human trial, the prote...