Technique for genetically modifying blood stem cells brings cure for blood diseases closer
...r biological ferry composed of DNA housed within a harmless virus--to shuttle a therapeutic gene into the defective HSCs. The gene allowed red cells that were derived from the HSCs to make gamma-globin, a protein that acted as a substitute for beta-globin. The resulting Hb molecule, composed of alpha- and gam...INEEL uses extremophile bacteria to ease bleaching's environmental cost
... peroxide in industrial wastewater, producing only harmless oxygen and water as byproducts. Most important, the so-called extremozyme endures harsh industrial conditions better than currently available alternatives and lasts thousands of times longer. R&D Magazine declared the isolation and production of the ...Coke versus Pepsi: It's all in the head
...ing (fMRI). In this widely used imaging technique, harmless magnetic fields and radio signals are used to measure blood flow in regions of the brain, with such flow indicating brain activity levels.In the experiments, the sips were preceded by either "anonymous" cues of flashes of light or pictures of a Coke ...Ancient Chinese folk remedy packs anti-cancer punch
...a cancer cell recognizes transferrin as a natural, harmless protein and picks up the tagged compound without knowing that a bomb artemisinin is hidden inside." Once inside the cancer cell, the iron is released and reacts with the artemisinin. That makes the compound both highly toxic and, because o...ORNL system eliminates perchlorate, helps scientists trace source
...NL system removes and breaks down perchlorate into harmless chloride and water and recharges the resin so it can be reused many times. The process costs up to 80 percent less than conventional methods and is one of R&D Magazine's top 100 inventions for 2004. But Gu and ORNL colleagues Jusuke Horita and ...Insects implicated in the evolution of new human infectious diseases
...h as fleas and nematode worms, which are currently harmless to humans, but which could evolve quickly into a range of new diseases. As part of their research, Dr Nick Waterfield and Professor Richard ffrench-Constant (correct) from the University of Bath, and Professor Brendan Wren, from the London School of ...Evidence that learning is consolidated during sleep
...ts' brain regions. In PET, test subjects receive a harmless dose of radioactive tracer, and their brains are scanned as the tracer infuses through the brain. Blood flow through specific brain structures constitutes a measure of activity in that structure. The researchers found that the first group -- compared...Research uncovers role of Apolipoprotein E in Alzheimer's disease
...team found that ApoE is responsible for converting harmless AB into the toxic fibrous deposits, known as filamentous amyloid. The researchers showed that mice with ApoE possessed 3200 times more filamentous amyloid than those without the gene. Diffuse deposits of AB can occur in the elderly in the absence of ...Improved molecular switch could serve as sensor, medical tool
...ctamase and the maltose binding protein found in a harmless form of E. coli bacteria. Each of these proteins has a distinct activity that makes it easy to monitor. Beta-lactamase is an enzyme that can disable and degrade penicillin-like antibiotics. Maltose binding protein binds to a type of sugar called malt...How the brain is wired for faces
...ition tasks. In the widely used technique of fMRI, harmless magnetic fields and radio signals are used to measure brain activity as subjects perform tasks. In the fMRI studies, volunteer subjects were asked to discriminate differences between faces in which the parts were spaced differently, as well as differ...Where the brain harbors unconscious fears
...the commonly used brain imaging technique of fMRI, harmless magnetic fields and radio signals are used to measure blood flow in brain regions, which reflects brain activity. In their experiments, the researchers first asked the volunteers to fill out a questionnaire that determined their basic level of anxiet...Healthy mix of GI tract microbes are key to preventing allergies and asthma
...life to prevent the immune system from reacting to harmless antigens," Noverr explains. "We're coming at it from a different angle. Our emphasis is on what's going on in the GI tract." The link between lung and gut may not seem obvious at first. But Huffnagle points out that every time we swallow, particles o...Weill Cornell team develops fast-acting anthrax vaccine
... Dr. Crystal's team incorporated the gene within a harmless organism called an adenovirus. "The adenovirus delivers the gene to the mouse, and then the gene goes to work -- telling the animal's body to make this antibody against anthrax," Dr. Crystal said. The study found: Once inside the mouse's body, t...Tips from the journals of the American Society for Microbiology
...s the toxin responsible for botulism, is typically harmless in adults because it cannot grow in the presence of oxygen. But the bacteria have been known to grow in the intestines of infants under the age of 1, often resulting in weakness, paralysis and even death. The sudden onset of infant botulism followe...Key molecule in plant photo-protection identified
...other, where it can then be routed down relatively harmless chemical reaction pathways. Said Fleming, "This defense mechanism is so sensitive to changing light conditions, it will even respond to the passing of clouds overhead. It is one of Nature's supreme examples of nanoscale engineering." The light harve...The microorganism Staphylococcus epidermidis is harmless on human skin, but it is the leading cause of hospital-acquired infections and infections of indwelling medical devices. S. epidermidis is associated with an enormous number of infections in people with prosthetic joints, replacement heart valves, an...Researchers blend folk treatment, high tech for promising anti-cancer compound
...e cancer cell recognizes transferrin as a natural, harmless protein," Lai said. "So the cell picks up the compound without knowing that a bomb artemisinin is hidden inside." Once inside the cell, the artemisinin reacts with the iron, spawning highly reactive chemicals called "free radicals." The free radica...Amgen's decision to block reinstatement of GDNF is faulted by a leading Parkinson's advocacy group
...th appropriate waivers that would hold the company harmless in event of any complications, whether foreseen or unforeseen, and with the approval of the relevant Institutional Review Boards." "The safety issues of neutralizing antibodies (found in some of the human subjects) and of cerebellar degeneration invo...Spit, and call me in the morning
...'s possible to detect certain microbes - HIV and a harmless bacterium related to anthrax - from the microbes' genetic material detected in saliva. Malamud stressed the importance of technology that can be used right in the doctor's office. For example, doctors often put children with respiratory infections on......expressed around the dead bone. He then modified a harmless virus to carry these genes, devised a method of freeze-drying a paste containing the virus so it could be easily handled, and painted it directly onto a bone graft during surgery. Numerous tests in mice confirmed that the virus permeated the inflamm...