Doing nature one better: Expanding the genetic code in living mammalian cells
...imilar to threading a needle the channels flexible head feeds through a small portal and blocks the centra...g the hypothesis that the diameter of the flexible head plays a crucial role in the fast inactivation of this channel, adds Slesinger. ......Rico Irles, lecturer of Medicine of the UGR , and head of the research group, this low beta-endorphin level determines whether someone may become an alcoholic. When a subjects brain with low beta-endorphin levels gets used to the presence of an exogenous surplus, then, when its own production stops, a de...Critical protein prevents DNA damage from persisting through generations
...ing," says Michel, Sherman Fairchild Professor and head of the Laboratory of Molecular Immunology. "Because for it to be responsible, the breaks would have had to happen early on, the cell would have to divide, mature, maintain the breaks, and stay alive with broken chromosomes." This, in fact, was pre......ppens next if, as seems likely, all our efforts to head off a crisis come to nothing." He adds that, "Our impending demise is in this sense the ultimate in a social problem and it requires a collective solution." ...Scientists discover role of enzyme in DNA repair
.... Imagine a piece of DNA as a zipper, he says. The head of the zipper (the transcription complex) will repeatedly go through the two interlocked sides, coming to the broken part, and eventually falling off. One could imagine that this unzipping activity might interfere with the mechanism that is trying to...$125 million bioenergy initiative powered by Midwest ag industry, MSU research
...ironmental issues our universities already have a head start in studying these from many angles. There is tremendous compatibility between UW-Madison and MSU, and we have assembled with others a strong and dynamic partnership. Wisconsin, Michigan and the Great Lakes region will be a hub for research ef...A small leak will sink a great ship
...t fly where a mutant carries a pair of legs at the head instead of the two antennae. Indeed, experiments performed by the German and Dutch scientists showed that in the two plant species mutation in the same gene conferred altered identity to the floral organs. This gene turned out to code for a microRNA...K-State biochemist contributes to article in Science magazine
...nost is a distinguished professor of biochemistry, head of the department and a member of the K-State Arthropod Genomics Center. He was part of a group of international researchers whose work appears in the June 22 issue of Science. The researchers are working to understand how the immune systems in two t...Brain's inertial navigation system pinpointed
...r sensors in the inner ear yield information about head position only. Also, the vestibular systems detection of head acceleration cannot distinguish between the effect of movement and that of gravitational force. Do...Developer of new method for treating bone defects wins WPI Entrepreneurship Award
...l Kalenian, son of Aram and Alba, and McRae Banks, head of WPI's Department of Management and director of the university's Collaborative for Entrepreneurship and Innovation. The winner is selected based on the novelty of the invention, as well as its commercial potential and the likelihood of its success....The kapok connection -- Study explains rainforest similarities
...ok that grows taller than a 16-story building, its head poking above the forest canopy. Its flowers produce more than 50 gallons of nectar per tree in a season, attracting bats that travel as far as 12 miles between trees and transfer pollen in the process. When the seed pods ripen, they break open to r...Cytokine resistance contributes to pathology of type 2 diabetes
...he team, led by pathology professor and department head Gregory Freund, also had demonstrated that human monocytes cultured under type 2 diabetic conditions had impaired interleukin-4 signaling. Interleukin 4 (IL-4) is an important player in the immune response in that it steers macrophages toward the pro......s access to small rakes with either a rigid wooden head or a flimsy fabric head. Both enculturated and se...groups with two identical hybrid rakes. Each rake head had a rigid side made of wood (functional) and another side made of flimsy cloth (non-functional). ...New findings challenge established views on human genome
...very little about before, said Ewan Birney, Ph.D., head of genome annotation at the European Molecular Biology Laboratorys European Bioinformatics Institute (EBI) in Hinxton, England, who led ENCODEs massive data integration and analysis effort. The ENCODE consortiums major findings include the discove...Herpes virus hijacks DNA repair process
...in, M.D., Ph.D., Edward Mallinckrodt Professor and head of the Department of Pathology and Immunology, Tarakanova found that murine herpes virus, rather than the host cell, was triggering the DNA damage response. She showed that introducing just one viral protein into cells led to activation of two cellul...New findings challenge established views about human genome
...very little about before, said Ewan Birney, Ph.D., head of genome annotation at EMBL-EBI, who led ENCODEs massive data integration and analysis effort. The ENCODE consortiums major findings include the discovery that the majority of human DNA is transcribed into RNA and that these transcripts extensivel...Other highlights in JNCI, June 12
...with transplanted human nonsmall-cell lung cancer, head and neck cancer, stomach cancer, or prostate cancer were treated with deguelin or placebo twice a day for 15-28 days. The researchers showed that deguelin directly binds to Hsp90 and inhibits its functional activity, which results in a reduction i...Study helps preserve Arctic whale, Eskimo subsistence hunt
...west core body temperature. It uses its bow-shaped head to crack through the ice as it migrates north into the Beaufort Sea every summer and south into the Bering Sea for winter. Like all baleen whales, it uses specialized fibrous materials in its mouth to sift plankton from sea water. Bickham said som...Agonized death throes probable cause of open-mouthed, head-back pose of many dino fossils
...f many fossilized dinosaurs, with wide-open mouth, head thrown back and recurved tail, likely results from... are in this posture, exhibiting a classic pose of head thrown back, jaws open, back and tail reflexed backward and limbs contracted," said Kevin Padian, pr......ner enzymes that kill brain cells during stroke or head trauma also interfere with the normal disposal of an enzyme that helps generate plaque. This interference increases the level of the enzyme in brain cells, they found. The researchers, led by Giuseppina Tesco and Rudolph Tanzi of Massachusetts Gene...