Research team develops nonhuman primate model of smallpox infection
...gues examined the host gene expression patterns of hemorrhagic smallpox in these animals. Specifically, they documented fluctuations in cellular proliferation, interferon, and viral modulation of the immune response. A better understanding of the disease process that occurs with smallpox infection will aid in th...Tips from the Journals of the American Society for Microbiology
...ult in severe complications in humans ranging from hemorrhagic colitis to death. Previous outbreaks have been primarily associated with ground beef and raw milk, but a recent increase in cases involving highly acidic foods such as fermented dry sausages, mayonnaise, and apple cider have raised new concerns. In ...JCI table of contents April 1, 2005
...enace Liver damage after organ transplantation or hemorrhagic shock is due to a type of injury known as ischemia/reperfusion, occurring when blood flow is temporarily stopped and, upon restoration, leads to massive inflammation and death of liver cells. Studies have shown that a protein called NF kappa B plays...Researchers discover molecule that causes secondary stroke
...o 10 days following a massive brain bleed known as hemorrhagic stroke. Sixty percent of patients who survive the ...the blood-brain barrier," Dr. Clark says. "After a hemorrhagic stroke, however, toxins given off by the brain bleed contribute to the development of specific molec...Researchers report breakthrough against world's deadliest viruses
...often deadly viruses. Monkeys are known to develop hemorrhagic fever symptoms that are similar to those observed in humans infected by these viruses. Demonstrating that these vaccines are safe and effective in monkeys is a promising indicator of their real potential for use in humans. "When you see the tragedie...Fragment of yellow fever virus may hold key to safer vaccine
...online. These days, the horror of Ebola or Marburg hemorrhagic fever grabs more attention, but yellow fever is the original viral hemorrhagic fever. It strikes more than 200,000 people a year, mostly in Africa, killing about 30,000 of them, t...Experimental vaccine protects nonhuman primates from Lassa fever
... now Lassa virus, could have utility against other hemorrhagic fevers as well." "Lassa fever poses a huge public ...te of this virus is not as high as with some viral hemorrhagic fevers, there are many more cases of Lassa fever and a great number of survivors are permanently aff...Women's health study finds vitamin E does not protect women from heart attack, stroke, or cancer
...ease in risk of other types of bleeding, including hemorrhagic stroke. According to the 1999-2000 National Health and Nutrition Examination Survey, an estimated 13.5 percent of women in the U.S. take vitamin E supplements, although it is not known how many are taking the vitamin to prevent heart disease and str...The cost of dengue fever challenges public health and national economies
...ch person hospitalized with dengue fever or dengue hemorrhagic fever in Malaysia costs about $718 to treat. About 70 percent of the cost is paid for by the government, and the rest by insurers and individual households. This cost per patient is equivalent to 53 days of lost economic output, according to the stud...42 biomedical scientists worldwide named HHMI international research scholars
Tuberculosis, malaria, hemorrhagic fevers, and anthrax all are infectious and parasitic diseases posing a global problem that calls for a global solution. So the Howard Hughes Medical Institute (HHMI) is awarding $17.5 million to 42 outstanding scientists in 20 countries to tackle the...Medical leaders meet to commemorate National Biocontainment Lab construction start
... and treatments for diseases like anthrax, plague, hemorrhagic fevers, typhus, West Nile fever, SARS, influenza and drug-resistant tuberculosis," he said. Once completed, the six-story structure will house more than 12,000 square feet of maximum-containment biosafety level 4 (BSL4) laboratories where researchers...Tips from the Journals of the American Society for Microbiology
...e intestinal inflammation ranging from diarrhea to hemorrhagic colitis, with more severe cases afflicting children and the elderly. EHEC O157:H7 has also been identified as a bioterrorism agent. There is currently no specific treatment against EHEC infection and antibiotics are not recommended as they prompt t...CU virologist finds contagious equine flu in dogs
...ew weeks, although 1 to 5 percent die from related hemorrhagic pneumonia. From January to May 2005, outbreaks occurred at 20 racetracks in 10 states (Florida, Texas, Arkansas, Arizona, West Virginia, Kansas, Iowa, Colorado, Rhode Island and Massachusetts), according to the paper. "This infection will become a ma...Secrets to antibody's success against West Nile Virus surprise scientists
... virus and may be important to the onset of dengue hemorrhagic fever. This theory suggests that dengue and other viruses may have developed tricks that let them reproduce inside macrophages, the immune cells that normally consume and destroy any object that they find covered in antibodies. In effect, these tri...Computer models aid understanding of antibody-dependent enhancement in spread of dengue fever
...Enhanced virus replication triggers a more deadly, hemorrhagic form of the disease. A study published in the online edition of Proceedings of the National Academy of Sciences suggests that antibody-dependent enhancement offers an evolutionary trade-off between advantage and disadvantage for the dengue virus. The...Improved blood safety measures from Pall can increase platelet availability
...simultaneous outbreak of multiple diseases (dengue hemorrhagic fever, malaria and typhoid)....Tulane receives multi-million grant for hemorrhagic fever research
...ne of the deadliest group of diseases called viral hemorrhagic fevers. In partnership with the U.S. Army Medical...agnostic tests for the Lassa fever virus and other hemorrhagic fevers. "This project has importance for the public health and also for biodefense, because these v...Gene-specific Ebola therapies protect non-human primates from lethal disease
... needed for viral replication. Ebola virus causes hemorrhagic fever with case fatality rates as high as 80 percent in humans. The virus, which is infectious by aerosol (although more commonly spread through blood and bodily fluids of infected patients), is of concern both as a global health threat and a potenti...Tips from the journals of the American Society for Microbiology
...al of Virology. Ebola virus (EBOV) causes a severe hemorrhagic fever in humans and nonhuman primates resulting in death in 90% of those infected. Two particular species, Sudan ebolavirus (SEBOV) and Zaire ebolavirus (ZEBOV), have been responsible for the deadly human outbreaks that have occurred in Africa. To ......animal species. The Lagovirus genus causes a fatal hemorrhagic disease and hepatitis that has killed millions of rabbits across four continents in the past 20 years. In more than 30 years of research, part of what has been found to be unusual about caliciviruses is that they can cause multiple diseases and affec...