Gene variant is associated with brain anatomy, clinical course of ADHD
... JAMA/Archives journals. ADHD is among the most heritable of neuropsychiatric disorders, according to background information in the article. Several genes have been identified as possibly associated with the condition. One of the most frequently cited is a polymorphism or different type of the dopamine D4 r...New model for autism suggests women carry the disorder and explains age as a risk factor
...itional thinking about genetic disorders as purely heritable from a parent. This has implications for other disorders such as morbid obesity, schizophrenia, and congenital heart disease....Scientists seek useful traits in wild cottons
...ng obsolete and wild cottons for several positive, heritable traits," Gannaway said. "The data from these experiments should give molecular breeders more tools to work with as they look for ways to diversify, improve and expand our cotton gene pool. That will benefit global breeding stocks and lead to varietie...CSHL scientists confirm genetic distinction between heritable and sporadic cases of autism
Autism is thought to be the most highly heritable of all neuro-psychiatric disorders. Yet, most case...nd Michael Wigler, has found a distinction between heritable and sporadic forms of the disease. These findings may influence future autism research and diagnosti...Gene elevating breast cancer risk also causes prostate cancer
...luate the newly detected PALB2 gene as a potential heritable breast cancer susceptibility candidate by screenin... this Finnish founder mutation may be important in heritable prostate cancer as well. Male breast cancer and colorectal cancer cases did not display the mutation......fects." The results show that at least 10-20% of heritable variation in gene activity is due to CNVs. The team found associations that included previously known examples, such as UGT2B17, which has been associated with prostate cancer, proving that the new approach works well. They also showed for the firs...FISH-ing for links between cancer and aging
...ualizing chromosomes of cells from patients with a heritable premature aging disease known as Werner Syndrome. In a study to be published in this week's online edition of the Proceedings of the National Academy of Sciences researchers led by Jan Karlseder, Ph.D., assistant professor in Salk's Regulatory Biol...Cambridge led team discovers gene mutation which prevents carriers from feeling pain
...o been found to contribute to ongoing pain in some heritable human disorders. As individuals with mutations in the gene SCN9A are otherwise healthy, the scientists are hopeful that the development of drugs that prevent Nav1.7 from functioning could be used as new and potentially safer pain medications.......of methods that our cells have evolved to transmit heritable changes without changing DNA. Among other things, epigenetics is crucial to differentiation, the process which makes one cell from another, and thus is at the heart of the mystery of stem cells. Genomic imprinting is a type of epigenetic change...Authoritative new book on epigenetics published by CSHL Press
...e quirky characteristics. Epigeneticsthe study of heritable traits that are not attributable to alterations in DNA sequencehas provided substantial insight into fundamental biological processes, including the development of stem cells, the mechanics of gene regulation, and the basis of some human diseases. T...American research finds twins more likely to have premature menopause
...twins and mother-daughter pairs had shown a strong heritable component for menopausal age, although the genetic factors responsible were still largely unidentified. The current study was consistent with this finding insofar as identical twins had lesser disparities in menopausal age than non-identical twins. I...Gene linked to autism in families with more than one affected child
...utism candidate genes." Autism is one of the most heritable mental disorders. If one identical twin has it, so...an development. "We know that autism is the most heritable of neuropsychiatric disorders, but, thus far, we have not identified genes that consistently are ass...Crickets on Hawaiian Island develop silent wings in response to parasitic attack
...e Hawaiian Islands, underwent a mutation a sudden heritable change in its genetic material that rendered it incapable of using song, its sexual signal, to attract female crickets, according to a new study by UC Riverside evolutionary biologists. In addition, the researchers found that although the new mal...In a technical tour de force, Salk scientists take a global view of the epigenome
...ies in a field known as epigenetics - the study of heritable changes in gene function that occur without changing the letters of the DNA alphabet - show that how a cell "reads" those letters is critical. Methylation is chemical modification of one letter C (cytosine) of the four letters (A, G, C, and T) rei......d fellow researchers discuss how this phenotype is heritable on an ecosystem level. That is, the progeny of a tree are likely to support the same communities of organisms and ecosystem processes that their parents supported. It's a premise with far-reaching implications. Consider, for example, conservation ef...USC study shows environment plays big role in women starting to smoke
... communicated with each other at least weekly, the heritable effect was reduced. This may indicate that the heritable effect in men could be overestimated or able to be affected by environmental factors." But when it c...Natural selection in island sheep
...rrelation between birth weight and survival, and a heritable basis for variation, attributed to maternal geneti...rowing bigger and bigger because there's a lack of heritable variation for selection to act on in harsh environments and there's a lack of selection to act on hi...Genetic factors, neuroticism may be associated with future development of anorexia
...h twins, anorexia nervosa appears to be moderately heritable and linked to neurotic behavior early in life amon...verweight later in life. Anorexia is a moderately heritable psychiatric disorder that may be predicted by the presence of early neuroticism."...Escapee farmed salmon infiltrate fitter wild populations
...onmentalists are concerned about farmed salmon yet heritable changes that have accumulated in farmed strains at the genetic level are largely unknown. In new research published in the journal Molecular Ecology, researchers have found scientific evidence that farmed salmon have evolved genetically differently t...Genetic factors important in development and timing of Alzheimer's disease
...of twins, Alzheimer's disease appears to be highly heritable and genetic factors may also influence timing of the disease, according to an article in the February Archives of General Psychiatry, one of the JAMA/Archives journals. Two-thirds of adults aged 65 years and older with dementia have Alzheimer's disea...