Pesticides may promote Parkinson's disease and exercise may offer protection
...s also showed that the amount of COX-2 protein was higher in patients with Parkinson's disease than in those without the disease. "These results show that there is a relationship between the disease and the presence and amounts of this protein in the brain," says Przedborski. Of the different cell death m...Potential new oncogene may be missing link in cancer-causing chain
...east cancer," he says. "We found the LRP6 gene had higher than normal activity in five of the eight breast tumors we tested. So, it appears that an increase of LRP6 alone may lead to breast cancer in these cases." Next Bu and his colleagues plan to screen a larger group of breast cancer samples to see how ...GENEPI: a tool to refine and fine-tune radiotherapy treatment for cancer
...mated that 5-10% of cancer patients could tolerate higher radiotherapy doses, which would boost their chances of survival when using methods for accurately assessing individual radio-sensitivity", said Dr. Hlscher. "The data provided by GENEPI will contribute to a significant benefit in terms of reducing th...Passage of Marin County GMO ban would encourage widespread use of harsh pesticides
...ically engineered rice, known as Golden Rice, with higher levels of beta carotene is a new tool that can be used to address Vitamin A deficiencies in the diets of people in much of the developing world. Lack of vitamin A causes millions of cases of blindness among children of poor nations as well as many ...Genetically endowed worm may substitute for rodents in some toxicology testing
...s and proteins that function similarly to those of higher animals, including humans. Freedman, an associate professor of environmental toxicology who has worked with C. elegans since graduate school, now seeks to apply this extensive knowledge about the roundworm's biology to answer questions involving toxi...New Italian research links migraine and endometriosis
...d evidence that women with endometriosis[2] are at higher risk of having migraine. A team from the Universit... that the prevalence of migraine was significantly higher among the women with endometriosis. Double the number of women in the endometriosis group had migrai...Evidence that learning is consolidated during sleep
...ined group, they found that the first group showed higher activity. Next, the researchers tested the trained...ctivity measured during sleep. They found that the higher the gain in post-sleep performance, the higher had been their NREM brain activity during sleep. No s...'Broken' gene reveals evolution of salt retention and possible ties to hypertension
...t among the Mandenka of Senegal (12N). Rates were higher among populations in East Asia, ranging from 55 percent among the Dai of China (21N) to 75 percent among Han Chinese (32N) to 77 percent among Japanese (38N) and 95 percent among the Uygur of China (44N). Rates in Europe are uniformly high, ranging ...Stress impairs thinking via mania-linked enzyme
...he cognitive functions of the prefrontal cortex, a higher brain region that allows us to appropriately guide our behavior, thoughts and emotions," explained Arnsten. "PKC activation led to a reduction in memory-related cell firing, the code cells use to hold information in mind from moment-to-moment. Exposu...Fat buildup found in hearts of obese or diabetic heart failure patients
...ese patients suffering advanced heart failure have higher levels of fat embedded in their hearts and greater molecular evidence of haywire cardiac metabolism, a research team led by cardiologists at The University of Texas Medical School at Houston reports in the November issue of the FASEB Journal. Heart f...JCI table of contents November 1, 2004
...TITLE: c-Cbldeficient mice have reduced adiposity, higher energy expenditure, and improved peripheral insulin action AUTHOR CONTACT: David E. James Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, NSW 2010, Australia Phone: 61-2-9295-8210; Fax: 61-2-9295-8201; E-mail: d.james@garvan.org...Other highlights in the November 3 JNCI
...ith a body mass index (BMI) of 30 or greater had a higher risk compared with women with a BMI between 20 and 22.9. BMI at age 20 and BMI gain since age 20 were also associated with endometrial cancer risk. In addition, women who spent 90 minutes or more each day doing physical activities had a lower risk of...Study reveals genetic link to colon cancer
...pared to non-carriers, the MYH gene carriers had a higher risk of acquiring colorectal cancer. ...People cause more soil erosion than all natural processes
...d 1,500 feet per million years, and rates are even higher in other parts of the world. Natural processes operate over areas larger than those affected by agriculture and construction, but even taking that into account, "the bottom line is, we move about 10 times as much sediment as all natural processes put...U-M researcher examines the cell's housekeeping habits
ANN ARBOR, Mich---The cells of higher organisms have an internal mechanism for chewing u...e with suppressed autophagy also appears to have a higher rate of spontaneous tumors, Klionsky said. Autophagy helps the cell fight infection by some kinds o...Sexual competition drives evolution of a sex-related gene
... species with more promiscuous females showed much higher rates of protein evolution than species with more monogamous females," said Lahn. The researchers measured protein evolution rates by counting the number of amino acid changes in the protein, then scaling it to the amount of evolutionary time taken t...A new target for control of obesity
...ty-first century, with the affected individuals at higher risk for diabetes, heart disease, hypertension and cancer, collectively known as metabolic syndrome. Shp2, a Src homology 2-containing tyrosine phosphatase, was discovered by Dr. Feng and others over a decade ago. It is present in each cell type ...High-predator environment has unexpected impact on aging in fish
... mortality rates throughout their lives. They have higher fecundity throughout their lives, plus the rate at...density of the survivors who, in turn, experienced higher food availability. More resources for the survivors can offset some of the predicted effects of high...Scientists uncover secret to sharp teeth
...ed at low levels in active ameloblasts and at much higher levels in the dental epithelial cells lining the enamel-free surface of the incisors. Mice engineered to lack follistatin had functional ameloblasts on the normally enamel-free surface adjacent to the tongue. Further investigation revealed that fol...Global warming's impact on US plants, animals determined from review of dozens of studies
...red fox have been gradually moving northward or to higher elevations, where more tolerable climate conditions now exist. Some of these species are also disappearing from southern, or lower elevation, portions of their ranges. These shifts sometimes have had no overall negative impact. But in other cases, t...