Tips from the Journals of the American Society for Microbiology
...rains of the virus. Because influenza strains are highly variable, a vaccine with higher efficacy is necess...ains and should induce long-lived responses and be highly efficient," say the researchers. In the study mice challenged with two str...Laboratory test of evolutionary theory confirms importance of links between populations
...the genetics involved in these natural systems are highly complicated, however, and even long-term studies can only address a limited number of questions, he said. "This laboratory system gives us a halfway ground between the mathematical models and natural populations. It allows us to test whether our assu...Time-lapse movies show brain cells move like a two-stroke engine
... and a trailing end. Because migrating neurons are highly polarized, Hatten and her coworkers suspected that mPar6-alpha was active in them. Again, the researchers used Venus, this time to label mPar6-alpha protein. Its bright yellow glow concentrated in the centrosome, the organelle located just in front o...Muscling in on a deadly cancer
...sarcoma, but until now, no mouse had developed the highly lethal alveolar rhabdomyosarcoma. Capecchi says cancer specialists have believed alveolar rhabdomyosarcoma originates in satellite stem cells because the tumors proliferate after birth, when stem cells retain their ability to pro...Ancient Chinese folk remedy packs anti-cancer punch
...with the artemisinin. That makes the compound both highly toxic and, because of cancer's rapacious need for iron, highly selective. Surrounding, healthy cells are essentially undamaged. "Our research in the lab i...NHGRI seeks next generation of sequencing technologies
...colony (polony) sequencing technologies. This is a highly parallel sequencing approach that involves synthes...p of researchers will work on further developing a highly integrated and parallel format with improved equipment for detection of the chemiluminescent signals...Amphibians in dramatic decline; Up to 122 extinct since 1980
...garded as "canaries in the coal mine," since their highly permeable skin is more immediately sensitive to ch... In the Americas, the Caribbean and Australia, a highly infectious disease called chytridiomycosis has hit amphibians especially hard. New research is showi...Study identifies target for preventing sexual transmission of HIV
...eriment, Dr. Lederman and his colleagues applied a highly concentrated solution containing the altered chemokine to the vaginal membranes of rhesus macaque monkeys and challenged them with high doses of a virus that combined the outer surface of HIV and the inner workings of SIV so called SHIV. The soluti...Scientists identify new cause of obesity
.... "Clearly, this receptor is crucial to the body's highly sensitive ability to balance food intake and energy expenditure," Vaisse said. In the on-going UCSF Genetics of Human Obesity Study directed by Vaisse, researchers have so far studied the genetic profiles of about 2,000 patients. Of these, 50 have be...Research gaining momentum by silencing genes
...to use the collection to study plant proteins in a highly targeted manner....New version of tumor-suppressor linked to progression of childhood cancer
...ly as a cancer suppressor in neuroblastoma (NB), a highly aggressive and deadly childhood cancer. The study, published in the October issue of Cancer Cell, reveals new evidence about what stimulates progression of neuroblastoma and may provide a likely target for new anti-cancer therapies. Neurotrophin tyro...Discovery might improve design, effectiveness of anti-cancer drugs
...er laboratory studies, Wolfenden said. Since it is highly sensitive and accurate, mass spectrometry is a major analytical tool capable of sequencing peptides and allowing researchers to identify and characterize proteins at their physiological level. The instrument in which the experiments were performed is......e of 1 to 7 for their emotional impact showed that highly emotive words such as fear or hate also triggered colours. Words associated with positive emotions tended to elicit pink, orange, yellow, and green, whereas words associated with negative emotions triggered brown, grey, and black. Whilst it is q...Dr. Harris receives NIH Javits Neuroscience Investigator Award
...gical science field and likely will continue being highly productive for the seven-year term of award funding. Dr. Harris, Georgia Research Alliance Eminent Scholar in Synapses and Cell Signaling, was nominated for the award by Dr. Yuan Liu, program director in Channels, Synapses and Circuits; Technology ...To save dolphin's dorsal fin experts combine medical technology and teamwork
...the medical treatment wands are cool to the touch, highly portable and do not damage the skin of dolphins or humans. Thermal imagery revealed patterns of increased vascular development in Liko's dorsal fin and more rapid healing following application of localized LED therapy. Human cosmetic surgeon Dr. Fari...New insight into progression of colorectal cancer
...cancer to show that carcinogenesis in the colon is highly dependent on TGF-b production in tumor infiltrating T lymphocytes. Specifically, a form of the cytokine interleukin (IL)-6 was shown to play a key role and inhibition of TGF-b-dependent IL-6 trans-signaling prevented tumor progression. The researcher...Stony Brook University medical researcher developing new medication to prevent colon cancer
... colon and other cancers. He is now developing the highly promising nitroaspirin for the prevention of colon and pancreatic cancer, being supported by five NIH grants. He also pioneered the application of infrared spectroscopy to biology with emphasis on cancer, and holds several relevant patents. He is the...Large-scale forces shape local ocean life, global study shows
...ures to hide, so estimates would be comparable and highly accurate.To get a true snapshot of the diversity of these species around the world, Witman and his team chose 12 distinct biogeographic regions and randomly sampled at a total of 49 sites within these regions, which included the Gulf of Maine, Icelan...Early life stress can inhibit development of brain-cell communication zones, UCI study finds
...emy of Sciences . "These findings may prove to be highly relevant for understanding the origins of several human brain disorders, and they also point to some potential preventive treatments," said Baram, the Danette Shepard Chair in Neurological Studies. "The activation of stress hormones and molecules see...International human genome sequencing consortium describes finished human genome sequence
...s S. Collins, M.D., Ph.D. "The availability of the highly accurate human genome sequence in free public databases enables researchers around the world to conduct even more precise studies of our genetic instruction book and how it influences health and disease." One of the central goals of the effort to a...