Other highlights in the November 3 JNCI
... colleagues found that, in an animal model, adding histamine to melphalan in ILP improved tumor response compared with melphalan alone. They state that these results warrant further evaluation in a clinical setting. Contact: Timo L. M. ten Hagen, Daniel den Hoed Cancer Center, t.l.m.tenhagen@erasmusmc.nl Al...UO study is first to link histamine receptors to heat stress
...degree student's research is the first to identify histamine receptors as contributing to increased blood flow ...rst study designed to examine a potential role for histamine receptors in skin blood flow in humans. They tested the H1 and H2 histamine receptors and found that...Disease diagnosis, biodefense among UH chemical research projects
...trophorins in storing and releasing NO and binding histamine by using resonance Raman spectroscopic techniques as a probe of molecular structure. Yuriy Fofanov, assistant professor of computer science and assistant professor of biology and biochemistry, and Richard Willson, professor of chemical engineeri...Histamine, anxiety and alcoholism
In the brain, histamine regulates a wide variety of physiological processe...h are associated with a functional polymorphism of histamine N-methyltransferase (HNMT) called Thr105 allele, may also result in higher levels of anxiety which m...New analysis services for the wine-producing sector
..., the technique used is also HPLC. The presence of histamine in wines (due to the decarboxylation of the histidine amino acid by heterofermentative Lactobacillus), while not being a major health problem, has an effect on the quality of the wine, and so its control is necessary in a number of trading transactio...The relationship between lawns and allergies and asthma
...nhaled allergens such as pollen and fungal spores, histamine and other compounds that produce an allergic reaction are released. According to the National Institute of Allergy and Infectious Diseases, more than 50 million Americans, or one in six, have allergies. That makes allergies the sixth-leading cause o...VCU study shows hormone-like molecule kills cells that cause inflammation in allergic disease
...an, mast cells are packed with granules containing histamine and are present in nearly all tissues except blood. When mast cells are activated, inflammatory substances such as histamine, heparin and a number of cytokines are rapidly released into the tissues and blood, promoting an allergic reaction. Mast cel...Scientists exploring inflammation in rheumatoid arthritis make unexpected discovery
...ators made the even more unexpected discovery that histamine was responsible for the joint blood vessel leakiness -- in fact, the researchers could mimic the effect of the antibodies on blood vessel leakiness by just injecting histamine. Other researchers participating in the study included Pratik R. Patel, He...University, VA hospital launch nation's first comprehensive meth research center
...mediates these long-term impairments, and that the histamine system may be an important link to developing an effective target for drug therapies. One of the most important components of the MARC is its education program. Headed by William Cameron, Ph.D., OHSU associate professor of behavioral neuroscience, t...News tips from the Journal of Neuroscience
...mbined with neurobiotin juxtacellular labeling and histamine immunochemistry to precisely identify TMN histaminergic neurons. Their results demonstrate that these neurons are not active during sleep but exhibit slow ( 4. Phox2b, Central Chemoreceptors, and Hypoventilation Ruth L. Stornetta, Thiago S. M...Histamine tied to changes in blood pressure during exercise-recovery period
...w to the brain. "There is reason to believe that histamine is the primary vasodilator contributing to post-ex...ation of these two receptors for histamine." The histamine receptors involved are known as H1 and H2. Fexofenadine, which is the generic name for Allegra, work...Potential new therapeutic target for asthma, allergies and cancer
...ecrete a number of inflammatory substances such as histamine and S1P when activated by an inflammatory stimulus. Spiegel said that S1P in turn amplifies allergic and inflammatory responses. Therefore, S1P secreted from mast cells can orchestrate many allergic responses, including asthma, she said....VIP's importance to temperature regulation may be pre-empted by substance P
...Minson and additional colleagues reported that the histamine 1 receptor, which is involved in seasonal allergies, has a role in skin blood flow changes during heat stress. Minson's research primarily focuses on the basic physiological mechanisms of skin blood flow, but he also collaborates with scientists el...All itches not created equal -- Different parts of brain activated depending on cause
...llergy triggers -- allergens (pollen and dust) and histamine (allergy cells within the body caused by foods, dr... forearm. Non-atopic subjects were challenged with histamine and saline on two consecutive days. The subjects rated itch intensity continuously on a scale of ...News tips from the Journal of Neuroscience
...tein-coupled receptors (G q PCRs), specifically H1 histamine receptors, regulate Munc131, a protein that binds ...se depolarization protocol, the authors found that histamine increased the size of the readily releasable pool (RRP) of vesicles, and specifically increased prim...White blood cells in lung produce histamine seen in allergies
...he first to show that lung neutrophils can produce histamine in significant quantities, according to principal ...rancisco. Caughey says the result could mean that histamine acts as a link between airway infections and asthma and bronchitis, which are associated with allerg...