UNC Lineberger researchers identify molecular markers of aging
...he component cells that make up the tissues in the human body and are found in particularly high number in the bone marrow, as well as organs such as the skin, kidney and liver. "As tissue stem cells age, they appear to express more p16INK4a and ARF, which would stop those cells from replenishing," Sh...Cell enzyme may help suppress cancer development
...mined the PTPRO gene for methylation in 43 primary human lung tumors and their matching normal adjacent tis... When the researchers modified laboratory-grown human lung-cancer cells to over-produce the PTPRO enzyme, they showed that the cells proliferated more slo...Scientists find acid rain an unlikely ally in the battle against a greenhouse gas
...g our planet, is produced by natural processes and human activities. Increased amounts of methane and other greenhouse gases in our atmosphere are warming the Earth beyond its average temperature. Carbon, heat and moisture are known to influence methane production by members of the Archaea, single-celled...Powerful 'toolkit' developed for functional profiling of yeast genes
...yeast genes have at least one clearly identifiable human counterpart, the advance, described in the Nov. 5 ...cular Cell, should speed advances in understanding human gene and protein functions, as well as improve the reliability of what scientists think they know ab...NJIT stem cell researcher to receive research award from biomedical group
...rated in November. NJABR is dedicated to improving human health through biomedical research. "Collectively and individually, these scientists epitomize the caring leadership that characterizes our state's biomedical research initiatives," said Michael D. Kastello, chairman of the NJABR Board of Directors...New study reveals locations of possible Alzheimer's genes
...ity Medical Center have found two locations in the human genome that may harbor genes that increase the risk of Alzheimer's disease. If confirmed, they will be the first genes linked to Alzheimer's disease since ApoE4 was discovered in 1993. The findings are published in the November issue of Molecular Psy...Mayo researchers define celecoxib pathways and mechanisms for tumor reduction
...stasis in humans. "The MTag mouse model for human metastatic breast cancer is a helpful and important model in which to evaluate therapeutic strategies and to understand the mechanisms associated with therapy-induced growth inhibition," said Mukherjee. "This model allows us to proceed with preclinic...Virginia Tech, TIGR sign memorandum for new alliance
...nctional genomics, which have many applications to human health, agriculture, and biodefense. "This agreeme...logy and computational tools to protect animal and human life. The university is home to the Fralin Biotechnology Center and the Virginia Bioinformatics Inst...Stowers Institute scientist named American Cancer Society research professor
...or highest quality basic research and relevance to human disease," said Robb Krumlauf, scientific director of the Stowers Institute. ...Molecular switch provides clues to remarkable adaptability of human pathogen
...may play a key role in the ability of an important human pathogen to sense and adjust to its surroundings. ...olonization to chronic infection in this important human pathogen," explains Dr. Lory. Further, the observation that a number of genes with no known functio...International marine survey of coral death
...ture and diversity. "Ultimately this concerns the human community," says Susan M. Merkel, a Cornell microbiologist and coordinator of the project. "If we find that improvements in waste-water treatment, solid-waste disposal and land-use practices can slow -- or even reverse -- the destruction of coral ree...NYU team develops enhanced algorithm for detecting changes in cancer genomes
...d to account for the varied genomes present across human population. An earlier version of the algorithm as well as several other competing algorithms were capable of dealing with only cancer data or only polymorphism data and were unable to separate variations in cancerous and non-cancerous genes in a si...Global warming's impact on US plants, animals determined from review of dozens of studies
...n Climate Change involving Parmesan concluded that human use of fossil fuels was primarily responsible for the average hike in temperatures over the past 50 years. Gases released from spent fuel are known to enter the Earth's atmosphere, trapping extra sunlight there similar to the way a greenhouse works. ...Identifying the path to infection
...t stage of the infection, E. coli binds tightly to human kidney cells, using an 'adhesive protein' secreted...etermine how to stop E. coli from attaching to the human cell," said Li. The protein channel, known as "PapC," is a member of the "chaperone/usher" family...UO study is first to link histamine receptors to heat stress
...te, and Christopher Minson, assistant professor of human physiology and co-director of the UO Exercise and ... Led by Wong, the UO research team outfitted 11 human subjects in water-perfused suits and increased their core body temperature to about 100 degrees Fahr...Grants target better predictors for type 1 diabetes
... the recently revised estimate of 20,000 to 25,000 human genes and identified about 100 genes that may pred...will help the MCG researchers finish analyzing the human genome. "We want to look at everything. This grant will allow us to look at every gene we have," say...First Max Planck Partner Institute in China
...can lead to a deeper understanding of processes in human organs and ultimately to the development of new medications. The Partner Institute is going to work in a number of disciplines because only the combination of various disciplines in the life science, physics, and computer sciences will enable a bette...New Royal Society journal studies
...sy is whether moa were already in decline prior to human settlement. Using new genetic analyses on an extin...sts that moa numbers had already declined prior to human settlement, perhaps as a result of habitat loss through volcanism or disease. If our new estimates o...Tiny exosomes extracted from donor cells may be 'magic bullet' for drug-free transplants
...meters 1,000 times smaller than the diameter of a human hair yet each contains a potent reserve of major histocompatibility complex (MHC) molecules. MHC molecules are gene products that cells use to determine self from nonself. Millions of exosomes scurry about within the bloodstream, and while their fun...New program examines stem cells' potential to repair, replace damaged tissue
...learn more about stem cells over the lifetime of a human and why they seem to quit working as we age," says Dr. Isales of the multidisciplinary, multi-institutional group he's putting together. "Is it because the stem cells are becoming depleted. Is it because stem cells are dying out and not being replace...