Tag: "humanization" at biology news
Steven M. Larson named recipient of SNM's 2005 Georg Charles de Hevesy Nuclear Pioneer Award
...he problems of antibody production, radiolabeling, humanization
of the antibody, minimizing host immune response and developing methodologies to quantify response. Using carbon-14-labeled media and a sensitive radiodetector system, Larson was able to rapidly identify bacterial and cell growth, a technology that i...
High resolution 'snapshots' detail dynamics of a cocaine antibody
...is, Zhu pointed out, provides a foundation for the humanization
and mutagenesis of the antibody to enhance its cocaine-hydrolyzing activity and make future human clinical trials feasible. "Given the fact that catalytic antibodies have been produced with the same levels of efficiency as natural enzymes, it seems w...
Dartmouth and GlycoFi report full humanization of therapeutic proteins from yeast
... the Dartmouth/GlycoFi team announced the complete humanization
of the glycosylation pathway in the yeast Pichia Pastoris. "We've successfully completed one of the most complex cellular engineering endeavors undertaken to date," said Tillman Gerngross, chief scientific officer of GlycoFi and professor of engin...