deCODE discovers cause of major subtype of glaucoma
...and which were not included on the chip led to the identification of the two risk variants allele G of rs1048661 and allele G of rs3825942 strongly linked to XFG in Icelandic and Swedish case-control cohorts. A combined total of some 16,000 patients and control subjects participated in the study. Glaucoma is...Research aims to identify markers for menopausal women at risk for deadly blood clot
... not yet led to a risk profile, thereby precluding identification of women at risk. Now, a team of Mayo Clinic researchers, led by Virginia Miller, has developed a novel concept that uses blood platelets to define thrombotic risk. The team is testing its theory as part of the Kronos Early Estrogen Prevention Study ...Gold nanoparticles may pan out as tool for cancer diagnosis
...nd of routine and cost-effective procedure for the identification of cancer cells. A patient gives blood, from which cancer cells are obtained. Nanorods are then added to bind to specific markers, if present. Next, the cells are placed on a microscopic slide for imaging. After the rods absorb and re-emit radiation,...Defining the active site of Bax
...gomerization and apoptotic activity of Bax and the identification of the Bax homo-oligomerization domain represent one step forward towards answering that question," explains Dr. Luo....First new multiple sclerosis gene found in 30 years
...ay lead to novel treatments for the disease or the identification of targets for new therapies. The team used a technique known as genomic convergence, in which they took the results of many studies looking for common elements. From studies involving patients and their families in the United States and Great Brit...Study points to new way to predict death risk from torn aorta
...rogram in aortic diseases. It is also pursuing the identification of blood markers that might permit an earlier diagnosis both early in the course of a dissection and later on, and working to further refine long-term risk prediction, says Eagle. U-M surgeons G. Michael Deeb, M.D., Himanshu Patel, M.D., and Gilbert ...Air pollution link to clogged arteries
... microarray expression profiling. This allowed the identification of gene modules containing a high number of co-expressed genes. These modules appear to be activated by a combination of phospholipids and diesel particles and are linked to vascular inflammation pathways. To confirm these findings, the team exposed ...Contributing membership in the biomarkers consortium surges to 30 companies and nonprofits
...tection, diagnosis, and treatment of disease. The identification of biomarkers is an essential element for the new era of predictive, preventive, and personalized medicine in which the accuracy of individual health assessments will exceed those of today. Biomarkers will accelerate basic and translational research...A new method of adult stem cell growth efficacious in treatment of disorders of the cornea
...nd in a homogeneous manner, enabling a better cell identification in order to select the most suitable units for the treatment. This method permits finding out with precision the cell population that we are implanting in the eye and to verify, thereby, both the quality and quantity of the cells transplanted.Clnical...Decoding mushroom's secrets could combat carbon, find better biofuels and safer soils
...ch will also benefit growers and consumers through identification of improved quality traits such as disease resistance.The University of Warwicks horticultural research arm Warwick HRI will co-ordinate provision of genetic materials to the Joint Genome Institute in California for sequencing, will organise analysis...A decisive step toward a cure for insulin dependent diabetes
... a new, extremely powerful analysis method and the identification of a new gene involved is extremely important. The... it mistakenly identifies as foreign bodies. The identification of these genes will help advance research on two fronts: prevention and treatment. Prevention, as th...Story tips from the Department of Energy's Oak Ridge National Laboratory
...nimized through a new system that focuses on early identification and rapid response. The system, developed and operated by a team that includes Oak Ridge National Laboratory, integrates information obtained from diverse sources and automatically initiates an appropriate response. One facet that sets BWIC (biologic...JCI table of contents: July 12, 2007
... disease and necessary for EAE/MS persistence. The identification of this T cell subset suggests that these cells may be critical targets valuable to the design of therapies for autoimmune diseases such as MS. TITLE: A public T cell clonotype within a heterogeneous autoreactive repertoire is dominant in driving E......may force rethinking of current strategies for the identification of miRNA targets in cells with individual miRNA overexpression or deficiency, explains Dr. Tarakhovsky....Global community listens to TAU genetic researcher at EU Conference on Hearing Loss
...ing, educational development and employment. Early identification of such conditions and intervention are therefore extremely important for society.......evelop and the resulting male individuals make the identification of the species that much more reliable. Thus, in the case of collecting only females, they are kept in cages for a number of days until they lay eggs and these develop to produce a new generation, one which can be identified more precisely. Besides...Researchers identify genetic mutation that may alter tumor cell proliferation
...inhibitors. If validated by further studies, the identification of this recurring mutation has the potential to im...e for the role of AKT1 in cancer formation. The identification of the AKT1 mutation was a collaborative effort between Eli Lilly & Company and TGen. This discovery...JCI Table of Contents -- July 2, 2007
...Arthur Bank from Columbia University discusses the identification of AHSP as a unique hemoglobin helper and the role it may play in diseases in which alpha- or beta-globin production is altered. TITLE: An erythroid chaperone that facilitates folding of alpha-globin subunits for hemoglobin synthesis AUTHOR CONTA...Researchers find gene that spurs development of the epididymis
...o contribute to epididymal coiling, he said. The identification of inhibin beta A in the development of the epididymis is important for understanding the basic biology of male sexual development, Yao said. But it also provides new insight into male infertility. ......for response to treatment in all patients with the identification and validation of a cutoff point for a molecular target. They tested the design in a simulated trial and also used it to analyze data from an existing prostate cancer trial. In the simulation trial, the new design allowed the researchers to see whe...