Tag: "identified" at biology news

Tiny plant a model for commercially important trees

...nt. Chengsong Zhao demonstrated that one of the identified wood transcription factors showed potential as a r... further manipulating this gene and others we have identified as potential regulators of wood formation, we will have a better understanding of how plants produce...

Tips from the Journals of the American Society for Microbiology

...g, researchers from North Carolina and Oregon have identified a new class of compounds that block a key step in ...,460 potential I7L inhibitors. Additional testing identified a group of chemically related compounds, one of which was TTP-6171, that appear to block replication...

Random gene activation helps ulcer bug escape immune system

...cells of the stomach lining to feed, but the newly identified interaction ensures that a small reservoir of bacteria are always more loosely connected. This reservoir is much more likely to survive if the host mounts a strong immune response. "Basically, if you're holding onto someone's T-shirt and they start ...

Heart responds to fasting by remodeling vital energy-producing components

...on University School of Medicine in St. Louis have identified a previously unsuspected response by mouse heart muscle cells to fasting conditions: the cells' power generators, the mitochondria, appear to remodel and consume extra internal walls or membranes in an effort to supply energy to the rest of the cell....

UCI researchers use human embryonic stem cells to aid spinal cord injury repair

...In previous studies, Keirstead and colleagues have identified how the body's immune system attacks and destroys myelin tissue during spinal cord injury or disease states. They've also shown that, when treated with antibodies to block immune system response, myelin is capable of regenerating, which ultimately re...

Menssana research at NJIT receives kudos for FDA-approved breath test

...then mailed to the lab for analysis. Menssana has identified distinct patterns made by more than 200 different volatile organic compounds exhaled in every breath. Phillips has proved that these patterns vary with illness and can be used to diagnose a variety of diseases. "It's more than folk medicine," said ...

Flies on crack

...l process. From 400 different mutants, they identified seven with an increased response to cocaine, and for two of these, the disrupted gene was the same--Lmo. The Lmo protein, whose levels were reduced by the mutations, is known to regulate certain transcription factors during development. However, no d...

This is your fly's brain on drugs

...r to screen 400 different mutants, the researchers identified seven with an increased response to cocaine, and for two of these, the disrupted gene was the same, Lmo . While Lmo is found throughout the body, it is enriched in the brain, and its cocaine-related effects appear to localize in the ventral...

Researchers probe marine mysteries off the Alaskan coast

...the chemical source." The scientists also identified many new, previously unidentified deep-sea coral habitats, some possibly associated with the methane seeps. The expedition included an interdisciplinary team of Scripps researchers, including geologists, geochemists, biogeochemists, biologis...

Peripheral timekeeping: Mammalian cells outside the brain have their own circadian clocks

...ircadian rhythms in mammals. When clock genes were identified in the late '90s, they were found to be expressed rhythmically not only in SCN but also in many other tissues. Some of these studies used the firefly luciferase gene, introduced into cells with regulatory elements from a clock gene, so that cell cult...

Genetic discovery paves way to decode sense of smell in mammals

... in the lining of the nose. Scientists first identified olfactory receptors in mammals 10 years ago a dis... Through these experiments, the researchers identified seven new olfactory receptors that respond to different chemical odorants included in their test pan...

Scientists generate human islet precursor cells in culture

...slets were depleted. These migrating islet cells, identified as insulin-expressing cells, then transformed into more primitive precursor cells that do not produce insulin. These new cells, called human islet-derived precursor cells (hIPCs), reproduce easily. The researchers observed that the hIPCs showed subs...

A new species of amyloid peptide

Bethesda, MD Scientists have identified a new, longer species of amyloid β-peptide that has the potential to be a new target for the treatment of Alzheimer's disease. The research appears as the "Paper of the Week" in the December 3 issue of the Journal of Biological Chemistry , an A...

Scientists first to grow common cause of food poisoning in the lab

...t infamous norovirus, the Norwalk virus, was first identified after a 1968 outbreak at a school in Norwalk, Ohio..., Ph.D., two postdoctoral fellows in Virgin's lab, identified MNV-1, the first known mouse norovirus. Virgin's group showed that the mice's ability to fight MNV-1...

Differences in gene usage dramatically change bacteria's 'lifestyles'

...made Salmonella a persistent source of illness. He identified several areas in the bacteria's DNA known as "pathogenicity islands" -- clusters of genes unique to Salmonella that help it cause illness. When complete gene maps for both bacteria became available in recent years, his interests expanded to understan...

A global view of gene expression in the aging kidney

...g the power of functional genomics, this study has identified a set of genes that can serve as molecular markers for various stages of a deteriorating kidney. These gene sets can also serve as probes to shed light on the molecular pathways at work in the aging kidney, and possibly on the process of aging itself...

New pheromone creates buzz about the clout of older bees

...ereas only four (including this new one) have been identified as primer pheromones. Primer pheromones are more difficult to work with because they imparts behavioral changes in a much longer time scale, taking days or sometimes weeks to see an effect. Huang and his associates spent years futilely searching fo...

Horwitz Prize to be shared by Tony Hunter, Anthony Pawson

...impact throughout biomedical research. In 1986, he identified protein modules that recognize specific phosphorylated tyrosine residues and established that molecular protein interactions control signal transduction....

Novel AT2R gene transfer prevents hypertension-related enlarged heart, cardiac fibrosis

...if there are other candidates such as the recently identified ACE2, a gene that expresses beneficial peptides. To determine if AT2R provides cardioprotective effects against heart failure and/or myocardial infarction (heart attack). To see if the lentiviral vector system "can be used to drive AT2R expressio...

UT Southwestern initiating trials in humans for ricin vaccine

...duction inexpensive and safe. The DNA sequence was identified by Dr. Vitetta's group several years ago in its ongoing efforts to produce safer immunotoxins containing the A chain of ricin. Dr. Vitetta and her colleagues have used such immunotoxins anti-cancer drugs as experimental therapy in more than 300 can...

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