Tag: "idiopathic" at biology news
Academics work to help stressed-out cats
...e no apparent cause, and are categorised as feline idiopathic
cystitis (FIC). Earlier studies led us to believe that stress could be a trigger factor for FIC, and we wanted to identify differences in the cats' environments and temperaments which might be causing this condition." This latest, questionnaire-based...
Statins, other cholesterol depletors, may disrupt hypertension development: UCSD study
...rsity of California, San Diego (UCSD). In studying idiopathic
pulmonary hypertension (PPH), formerly called primary pulmonary hypertension, the UCSD team found "a previously unappreciated cellular and molecular mechanism for the disease process," Patel said, "which may be amenable to treatment with current and ...
Phase III clinical program evaluates lubiprostone
... evaluated by the FDA for the treatment of chronic idiopathic
constipation and associated pain and bloating in adults. The IBS-C clinical development program will include two phase III trials. Each trial will examine more than 500 patients for 12 weeks to evaluate the safety and efficacy of lubiprostone. "I...
Inheritance, smoking spawn mysterious and deadly lung disease
...ers are rising with as many as 15,000 new cases of idiopathic
pulmonary fibrosis -- a form of the disease having...y new directions. "We've known for some time that idiopathic
interstitial pneumonia can run in families," he added. "Currently there is no adequate animal model ...
Missouri genetic disorder's roots untangled by international team
...a history of a condition called X-linked recessive idiopathic
hypoparathyroidism (XLHPT): a portion of the X chromosome, a human sex chromosome, has been removed and replaced by a copy of a much larger section of genetic material from chromosome 2. Alterations of such large regions of genetic code that stably p...
Lung scarring diseases linked to genes and smoking
New research shows that idiopathic
interstitial pneumonia (IIP), a group of potential...ithin the first five years of being diagnosed with idiopathic
pulmonary fibrosis. The study appearing in the November 1 issue of the American Journal of Respirato...
New approach for genetic screening for syndrome linked to cardiac irregularities and sudden death
...ng QT interval; family members of individuals with idiopathic
ventricular fibrillation; and depending on results of further investigation, members of the general population to define the prevalence of known genetic variants of LQTS."...
Advanced genomics and proteomics improve the diagnosis and treatment of a deadly lung disease
...ife-threatening form of pulmonary fibrosis, called idiopathic
pulmonary fibrosis, lacks all the hallmarks of inf...excess amounts in the lung tissue of patients with idiopathic
pulmonary fibrosis, which may be a more appropriate target for therapy. Interstitial lung disease de...
Penn researchers awarded $1.1 million for Pulmonary Hypertension Center
...t will study the molecular and cellular origins of idiopathic
pulmonary arterial hypertension. IPAH is a rare ...aging. "What this center is really focused on is idiopathic
hypertension, hypertension with no known cause," added Jones. "We want to discover new molecular and...
U-M scientists target key cells and signals that trigger pulmonary fibrosis
...chain of events leading to a lethal disease called idiopathic
pulmonary fibrosis or IPF. Idiopathic pulmonary fibrosis is a progressive disease that kills 40,000 Americans each year. Exposure to toxic environmental agents like beryllium and silica dust can trigger IPF, but in most cases, its cause remains a mys...
Patient's generosity after death leads to possible clues for lung disease
...the first time begun to analyze the progression of idiopathic
pulmonary fibrosis (IPF), a degenerative illness distinguished by lung inflammation, scarring and diminished breathing capacity that typically leads to death within about five years of diagnosis. The project, involving the examination of lung tissue ...
A candidate gene for familial idiopathic pulmonary fibrosis identified
ELMOD2-gene is a prime candidate gene for familial idiopathic
pulmonary fibrosis, suggests the recent study publ...spital of Helsinki observed that the prevalence of idiopathic
pulmonary fibrosis distributed unevenly in Finland. The prevalence was two times higher in eastern a...
Pulmonary hypertension discriminates by race, gender
...American women have the highest mortality rate for idiopathic
pulmonary arterial hypertension (IPAH), according ...ted States, an estimated 500 to 1,000 new cases of idiopathic
pulmonary hypertension are diagnosed each year. "Idiopathic pulmonary hypertension is a serious ill...
Proteins may predict lung transplant rejection
... disease, cystic fibrosis, pulmonary hypertension, idiopathic
pulmonary fibrosis and other diseases. Patients who receive a new lung may suffer bouts of acute or chronic rejection. Acute rejection often responds to therapy. Chronic rejection, which results in scarring of the lung's airways following inflammat...
Top scientists meet for Global Conference on Stem Cell Therapy for Cardiovascular Diseases
... The first engineered cell study for patients with idiopathic
pulmonary hypertension, presented by Dr. Duncan Stewart. REPAIR-AMI: The largest randomized, placebo controlled study of bone marrow-derived cells in patients with STEMI, presented at TCT. The clinical outcomes from this landmark study will ...
Leicester breakthrough in eye disease
...iscovery of this gene will make a genetic test for idiopathic
X-linked nystagmus possible. So far it has not been understood what the causes of nystagmus are. The discovery of the gene will lead to greater understanding about the protein which is abnormal in nystagmus. "Our research also showed that the ex...
JCI table of contents: Jan. 18, 2007
...OLOGY: The more mutations the worse the disease in idiopathic
hypogonadotropic hypogonadism Idiopathic hypogon...genic mutations account for variable phenotypes in idiopathic
hypogonadotropic hypogonadism AUTHOR CONTACT: Nelly Pitteloud Massachusetts General Hospital, Bosto...
Takeda and Tap to promote Sucampo's Amitiza in the United States
...ubiprostone) approved for the treatment of chronic idiopathic
constipation in adults in the United States. Deve...umber of adults in the U.S. suffering from chronic idiopathic
constipation," said Mark Booth, president of Takeda Pharmaceuticals North America, Inc. "This is a ...
Gene mutations linked to hereditary lung disease
...scarring of the lungs with no effective treatment, idiopathic
pulmonary fibrosis (IPF) affects approximately 50,000 Americans annually, and like some cancers often is fatal within three years. As many as 20 percent of IPF sufferers are thought to have inherited genetic mistakes that predispose them to the dise...
Studies assess effectiveness of serotonin and nerve stimulants on irritable bowel syndromes
...i-Centre Study (Abstract #198) In patients with idiopathic
constipation, which occurs with no identifiable ca...al nerve stimulation is an effective treatment for idiopathic
constipation that is resistant to conservative treatment. As a result of this stimulation process, ...