NIH gives $8M to University of Pittsburgh School of Medicine for myositis research
... be autoimmune diseases. This means that the bodys immune system, which normally fights infections and viruses, for reasons unknown turns on itself and attacks the muscle tissue and sometimes skin, joints and lungs, causing rash, arthritis and shortness of breath. The University of Pittsburgh-led study w...Study begins to reveal clues to the cause and progression of sepsis
...g. 13 Not all patients with sepsis mount the same immune response, even when they look the same clinically,...ine, indicate that past interpretations of how the immune system responds to infection interpretations on which many experimental treatments were based were...Pollution causes 40 percent of deaths worldwide, study finds
...ironment -- contributing to cancer, birth defects, immune system defects and many other serious health problems. Soil is contaminated by many chemicals and pathogens, which are passed on to humans through direct contact or via food and water. Increased soil erosion worldwide not only results in more soi...Newly created cancer stem cells could aid breast cancer research
...an 100,000 of them into a mouse with a compromised immune system, it quickly developed massive, deadly tumors. In initial experiments, a few tissue slices revealed a primary tumor structure that resembled that of cancer patients with metastases. That prompted Ince to wonder whether the cancer cells he cre...Gene regulation, not just genes, is what sets humans apart
...hese species in the coding regions that govern the immune system, the sense of smell and the manufacture of sperm, but the coding regions of neural-related genes had shown very little sign of positive selection in these studies. Yet, as far back as 1975 when Mary-Claire King and Allan Wilson first said huma...JCI table of contents: Aug. 9, 2007
...ect was observed specifically in the precursors of immune cells known as myeloid cells. This study raises the possibility that genetic mutations in UREs might have a critical role in the development of cancer. TITLE: A distal single nucleotide polymorphism alters long-range regulation of the PU.1 gene in ......tional wisdom that even harmless bacteria and the immune response they provoke suck up the energy of the h...ing on the organism increases with age. The innate immune response to bacteria is similar in flies and humans, and it loses strength with age in both species....In limiting life span, study finds booming bacteria innocent
...es were accumulating so much bacteria and a robust immune response to that bacteria, its not limiting how lo... and other nutrients, the researchers noted. Since immune function is impaired with age, it might be expected that bacterial load would increase or be otherwi...High-intensity ultrasound may launch attack on cancer, wherever it lurks
...ls start to leak can trigger an alarm that enlists immune defenses against the cancerous invasion, according...suggest that once activated by the ultrasound, the immune system might even seek and destroy cancer cells, including those that have spread through the bloods...Penn researchers discover how key protein stops inflammation
...egulatory genes without disrupting other important immune responses. Such drugs could benefit patients with chronic inflammation and transplant recipients as well as those suffering with inflammatory diseases. In the future, the scientists aim to determine the components of the cell responsible for flaggi...Anthrax bacterium's deadly secrets probed
...terium may secrete proteins that subvert the hosts immune system, enabling the bacterium to infect cells or ...o but we think they help the organism to evade the immune response, says Professor Harwood. Were beginning to understand why Bacillus anthracis behaves in the...How cells change the pace of their steps
...ses such as tissue renewal and the function of the immune system. Cell motility also is an essential part of embryonic development as fetal cells undergo an orchestrated migration to form functioning tissues and organs. Poorly regulated cell motility during embryonic development may result in some neurologi...Immunity in social amoeba suggests ancient beginnings
Finding an immune system in the social amoeba (Dictyostelium discoid...distinguish self from non-self the hallmark of an immune system, said Kuspa. The speculation is that a requirement of multicellularity is that you develop sy...Identified mechanism in the malaria parasite to help it adapt to infected individuals
... of a merozoite, is exposed to antibodies from the immune system. Consequently, the proteins of the merozoit...may help the parasite to escape the host organisms immune responses, although the researcher points out that this is yet to be confirmed. The researchers di...Discredited Korean embryonic stem cells' true origins revealed
...at can treat disease without being rejected by the immune system. The team recently demonstrated in mice ...d be matched to patients on the genes that control immune rejection. Having all the genetic material come from the mother, as it does in parthenogenesis, redu...Chickadee, nutchatch presence in conifers increases tree growth, says CU-Boulder study
... eat, said Linhart. "Terpenes act a bit like an immune system by essentially fending off attacks by birds...esults of this study is that birds affect how this immune system functions." The study also showed that chickadees and nuthatches disrupt a mutually benefi...New strategy for treating allergic disorders
...icines for a range of clinical indications. The immune system Every day our immune system combats harmful substances and micro-organisms that seek to penetrate our body. However, if o...A low expression of MX2 gene exists in the white blood cells of narcoleptics
... finds that the MX2 gene, which is relevant to the immune system, is significantly less expressed in narcole...as been suggested that specific alterations in the immune system occur, and its important for pathophysiology of this disorder, said Tanaka. We thought that ...Marijuana component opens the door for virus that causes Kaposi's sarcoma
...s virus (KSHV), researchers say those with lowered immune systems, such as AIDS patients or transplant recip...offer cautionary evidence that those with weakened immune systems should speak with their doctors before using marijuana medicinally or recreationally. The...Phase II study of therapeutic vaccine shows efficacy in patients with metastatic colorectal cancer
...s a therapeutic vaccine, designed to stimulate the immune systems of patients who already have cancer. The v...lls, produces the tumor protein and stimulates the immune system, said lead study author Richard Harrop, Ph.D., vice president of clinical immunology at Oxfor...