Tag: "immune" at biology news
Gene variations directly link inflammation to an increased risk for lung cancer
...rigger an overzealous inflammatory response by the immune
system, leading to lung cancer. The variants, or...A and interleukin 1B, two signaling molecules that immune
system cells secrete in response to infection or tissue damage. Our findings help explain how heav...
Skin rash actually signifies better outcomes for pancreatic and lung cancer patients
...rash, but it could be due to the strength of their immune
system, and that is why they survived longer, Wacker said. In the second clinical trial (known as PA.3) that tested Tarceva and the chemotherapy drug gemcitabine against a placebo drug and gemcitabine in 521 patients with advanced pancreatic cance...
New medical implants should react with the body, not seek to be inert
...are reasonably successful at hiding from the bodys immune
system, and are consequently not rejected. All the same, within a month of implanting them, the body isolates implants by wrapping them in a collagenous, avascular sac. Materials are considered to be biocompatible if this sac is not too thick. That...
From clinical cancer research: rethinking therapeutic cancer vaccine trials
...t to show evidence of vaccines spurring a patients immune
system to shrink tumors -- yet patients who receiv...hat trials do not show the vaccines can induce the immune
system into shrinking tumors, said Jeffrey Schlom, Ph.D., chief of the Laboratory of Tumor Immunolog...
Waging war on the deadliest superbug
...ays of incapacitating the bacteria and leaving the immune
system to deal with the infection. This will reduce the selection pressure for antibiotic resistance that arises from the use of traditional antibiotics. Professor Richard James, Director of CHAI said: We intend to apply for 5m over the next five y...
Chronically sleep deprived? You can't make up for lost sleep
... cognitive performance, as well as cardiovascular, immune
and endocrine functions. Sleep-restricted people also reported not feeling sleepy even though their performance on tasks declined. The Northwestern teams results suggest that animals may undergo a change in their need for sleep, or in their sleep h...
Researchers discover method for identifying how cancer evades the immune system
...e fundamental traits of a tumor how it avoids the immune
system might become its greatest vulnerability, a...indicate that a technique for determining a tumors immune
signature, could be useful for diagnosing and treating specific cancers. In the July 1 issue of Cl...
New clue why MS affects African-Americans differently than Caucasians
ST. PAUL, MN -- Differences in immune
systems have been found in African Americans with ...s show that ethnic differences in MS extend to the immune
response system, which plays a central role in MS, said study author John R. Rinker, MD, with the Wa...
Antibody linked to MS significantly higher in spinal fluid of blacks
...s among ethnic groups contribute to changes in the immune
system, affecting susceptibility to MS. And they a...udy measured cerebrospinal fluid levels of IgG, an immune
system antibody. Rinker and others have previously linked greater IgG to more aggressive MS in the g...
JCI Table of Contents -- July 2, 2007
...eatment of TB. TITLE: Neutrophil-mediated innate immune
resistance to mycobacteria AUTHOR CONTACT: Adrian R. Martineau or Robert J. Wilkinson Wellcome Trust Center for Research in Clinical Tropical Medicine, Imperial College London, United Kingdom. Phone: 44-207-594-3915; Fax: 44-207-594-3894; E-m...
New approach to pulmonary hypertension shows promise
...h-maintaining functions, such as the regulation of immune
cells and the development of the heart. However, it causes havoc when it is activated "inappropriately", such as in the case of pulmonary hypertension. "You can think of NFAT as a rogue air traffic controller that keeps planes in the air that need ...
Endometriosis increases the risk of certain cancers
...dometriosis disease. Or it could be defects in the immune
system that allow the endometriosis to grow and also might allow cancer cells to grow in different parts of the body. Maybe the treatment of endometriosis, hormonal or surgical, can influence cancer development. We do not know yet. Dr Melin plans t...
Tick-related disease thrives on cholesterol, study suggests
...ld kill an older person or someone with a weakened immune
system. She added that immune
function slowly declines and blood cholesterol levels typically increase as we age. The researcher...
New approaches to endometriosis treatment -- mouse experiments point the way
...has found that dendritic cells highly specialised immune
cells support angiogenesis by enhancing blood vessel growth. Using a mouse model of endometriosis, they found that these cells incorporate into the endometriosis lesions and enhance their growth. We also found that these cells have a similar effec...
Allergy molecule identified
...dentified the missing molecule that normally keeps immune
responses under control and appropriate. Having a food allergy means that the immune
system responds to a food protein as if it was harmful. The immune
system produces immunoglobulin E ...
Key to male infertility
A factor in immune
cells regulates human semen and seems to determine...in Institute for Medical Research have isolated an immune
substance called macrophage migration inhibitory factor (MIF) in semen samples from infertile and re...
Critical protein prevents DNA damage from persisting through generations
...or helping repair double-stranded breaks in DNA of immune
cells, but is also part of a system that prevents ...ivide. Early in the life of B lymphocytes -- the immune
cells responsible for hunting down foreign invaders and labeling them for destruction -- they rearra...
Breast cancer prognosis runs in the family
...r biology, response to therapy or vigilance of the immune
Biovest announces interim blinded data of fast-tracked pivotal Phase 3 clinical trial of BiovaxID
...fic vaccine designed to stimulate the patients own immune
system to recognize and destroy residual cancerous B-cells that remain after the patient has undergone chemotherapy. Unlike many other approaches to treating NHL, BiovaxID is designed to target only cancerous B-cells. The BiovaxID Phase 3 clinical ...
'Modular' leukemia drug shows promise in early testing
...f-destruction and by causing a particular class of immune
cells to attack them. In an animal model, the agent worked equally as well as the drug rituximab, now routinely used to treat chronic lymphocytic leukemia (CLL) patients. Rituximab targets a different protein on leukemia cells. The study by res...
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