Study shows big power of small RNAs, not just proteins, in halting cancer
...ing and even eliminate themselves by activating an immune response in surrounding healthy cells. Most suspected that proteins would be revealed as key to the power of p53, but this latest research published June 6 by Nature now identifies miRNAs as a critical force behind the anti-proliferation potential o...The insect vector always bites twice
...munogenic ones that can modulate or induce a human immune response. Working for the EpiVect programme initiated in 2003 (1), scientists from IRD research unit UR 024 studied this still little known response with the aim of identifying in the arthropod vector saliva the immunogenic proteins responsible. They...Finding protection from tumor growth in unexpected places
...ction from tumor growth when strongly expressed in immune cells. The related report by Shen et al, Mice with...lays roles in such diverse processes as fertility, immune cell development, and atherosclerosis, and a few studies have even suggested a role for ACE in gener...Stanford researchers find stem cells in colorectal tumors
...ll help find the weak points in cancer, devise new immune and molecular diagnostics and therapeutics, test them in mice that carry the cancer stem cells and, hopefully, in a few years begin to test them in our patients," Weissman said. The colorectal cancer stem cells highlight the importance of a protein...Discovery in orange cauliflower may lead to more nutritious crops
...mmon in developing countries, leads to compromised immune systems and is the leading cause of blindness in children. "A large percentage of the human population depends on staple crops for nutrition," said Li, an adjunct assistant professor in the Department of Plant Breeding and Genetics and a scientist at...NIAID supports research into etiology of fungal-induced inflammation in chronic sinusitis
...viously shown that CS patients have an exaggerated immune response to certain fungi, specifically Alternaria species. The patients reacted to the fungi with the production of the inflammatory mediators, which are crucial for the inflammation in CS, whereas healthy subjects were not reacting. The renewal o...JCI table of contents -- June 1, 2007
...ant moms exposure to flu vaccine kick-starts fetal immune system Some researchers have hypothesized that the fetus can be exposed to and mount an immune response against allergens to which the mother has been exposed, and this may have an effect on the ...Innovative smallpox vaccine research study to be conducted at Case Medical Center
...e the vaccine to all individuals, even those whose immune systems are suppressed, says Dr. Salata. Our hope is that the new vaccine will be a safer alternative to the current vaccine. UHCMC and the School of Medicine will act as a subunit of St. Louis Universitys Center for Vaccine Development, which is o...Pregnant mom's exposure to flu vaccine kick-starts fetal immune system
...ized that the fetus can be exposed to and mount an immune response against allergens to which the mother has...ed this technique to study cord blood B and T cell immune responses following maternal vaccination against influenza with Fluzone during pregnancy. The vaccin...New study suggests potential for a broadly-protective HIV vaccine
...HIV-1 surface protein, designated R2 gp140, and an immune response-boosting component. The researchers tested antibodies generated by the immunizations to determine their effectiveness in neutralizing the infectivity of a variety of HIV-1 strains. Antibodies produced as a result of immunization neutralized ...Cytomegalovirus exacerbates atherosclerosis through an autoimmune mechanism
...use of its ability to activate cells of the innate immune system involved in the initial phases of the disease. This new study therefore confirms that antibodies directed against Cytomegalovirus-derived proteins purified from patients with coronary artery disease induce endothelial cells damage and suppor...Genome of Clostridium botulinum reveals the background to world's deadliest toxin
...interaction with hosts, which involves evading the immune system and countering antibiotics to the single-minded opportunistic approach of C. botulinum....Story ideas from the Journal of Biological Chemistry
...gredient of the Indian herb turmeric, restores key immune cells that fight off cancer. The immune system of patients with advanced cancer is significantly weakened, mostly because the main cells tha...How plague-causing bacteria disarm host defense
... job of infecting the host by crippling the body's immune system. In essence, they knock down the front doo...ee bacteria species find their way past the body's immune system through a sophisticated invasion system that injects the effector proteins directly into the ...JCI table of contents: May 24, 2007
...nce Resistin is a small protein secreted by the immune cells monocytes and macrophages, and has been linked to insulin resistance, atherosclerosis, and inflammation. Recently, studies in mice have shown that resistin is present in the mouse hypothalamus and that it is capable of activating specific neuro......ne parasite that causes malaria in people. And the immune system of mice shows a different response to human...y modified it to produce an antigen that the human immune system recognises. Next, they genetically altered the mouses immune system to produce a human mole...Botulism bug has few genome wrinkles
...interaction with hosts, which involves evading the immune system and countering antibiotics - to the single-minded opportunistic approach of C. botulinum....Immune antibodies penetrate neurons to clear Alzheimer's-linked amyloid
...ve some clinical success with an antibody-directed immune therapy. Those hopes were dampened somewhat after ... exposed amyloid-filled neurons from these mice to immune antibodies similar to those used in clinical trials. They then examined changes in these cells in th...Parkinson's protein protects neurons from stress induced cell death
...ism which had been known for its prominent role in immune response. Usually, Parkinsons disease occurs after the age of 50 and in Germany about 400,000 people are affected. It is characterized by a decline of neurons in the so-called Substantia Nigra, a structure in the midbrain that produces dopamine. T...New data on the probiotic strain Bifantis shows anti-inflammatory properties
... The inflammatory response is a key part of the immune systems battle against invaders, but in certain co...s showed dramatically increased numbers of certain immune cells that control the immune systems response to harmful pathogens, in this case Salmonella. Bifan...