Tag: "immunity" at biology news
HIV-1's high virulence might be an accident of evolution
...ratchets down the activation of critical agents of immunity
called T cells following SIV infection, thereby limiting the detrimental effects otherwise caused by chronically strong immune activation. The HIV-1 Nef protein, and those of its closest related simian viruses, however, lack this protective function...
Speeding the search for elusive chromosomal errors
...deletion syndrome may have heart defects, impaired immunity
and developmental delay. Deletions of several genes in Prader-Willi syndrome may cause obesity and mental retardation. To seek out miniscule rearrangements in chromosomes, the Children's Hospital team employed the types of gene chips, or microarrays,...
AIDS vaccine research offers new insights on survival
...nto how a subpopulation of helper T-cells provides immunity
and promotes survival following infection with an ...h were vaccinated and six of which were not -- the immunity
generated by the vaccine controlled infection for approximately 100 days before levels of virus incr...
Immunology symposium to honor Dr. Robert Good's legacy
...ho translated his tremendous knowledge of cellular immunity
into the first successful bone marrow transplantation. Dr. Good, who died in 2003, spent nearly 20 years at the University of South Florida and All Children's Hospital, where an endowed chair in pediatric immunology was created in his name. More tha...
Plant-cell-produced technologies-cutting edge approach to bringing solutions to the market
...ry parts of the disease causing agent to stimulate immunity
in a manufacturing process that is totally free of animal components:"Being the first company to ever register a plant-made vaccine is another example of Dow AgroSciences' cutting edge approach to bringing highly novel and differentiated solutions to...
Rhesus monkeys in Nepal may provide new alternative for HIV/AIDS research
...sence of other alleles that are known to influence immunity
and the rate of disease progression in the animals, including one that is present in Indian rhesus macaques but not in the Chinese ones. Kyes, who also is a UW research associate professor of psychology, said the genetic analyses indicate the Nepal...
Children's Hospital Boston presents at the 2006 Pediatric Academic Societies annual meeting
...They believe their findings could be used to boost immunity
in these tiny infants, possibly making infections like respiratory syncytial virus, pneumococcus, pertussis, HIV and rotavirus much less of a threat. [2620.2] Unique Efficacy of Toll-Like Receptor 8 Agonists in Activating Human Neonatal Antigen-Prese...
Boosting newborns' immune responses
... is fully functional and can be harnessed to boost immunity
in these tiny infants, possibly making infections like respiratory syncytial virus, pneumococcus, pertussis, HIV and rotavirus much less of a threat. For about a decade it's been known that people's first line of defense against infection is a group ...
Lack of a key enzyme dramatically increases resistance to sepsis
... which appears to modulate inflammation and innate immunity
in humans, increases the body's "vulnerability to bacterial infection and septic shock" while a deficiency confers strong resistance to sepsis. This new discovery suggests that caspase-12 antagonists could be a potentially useful in the treatment of ...
Faster immune system testing set to improve poultry quality
...flu. Useful research and preventive tool Reduced immunity
is a serious problem for commercial poultry producers worldwide. The major cause is viral infection. All viruses can cause immunosuppression to varying degrees but Marek's disease, infectious bursal disease and chicken anaemia are particular concerns...
JCI Table of Contents, April 13, 2006
...en for presentation of multiple epitopes in cancer immunity
AUTHOR CONTACT: Jos A. Guevara-Patio University of... and viral escape as a consequence of heterologous immunity
AUTHOR CONTACT: Raymond M. Welsh University of Massachusetts Medical School, Worcester, Massachusett...
Farm study raises doubts about new approach to swine-disease control
...m. The hope is that the pigs will develop specific immunity
to that virus and will recover prior to breeding, ...t the approach boosted development and strength of immunity
against the local strain, but failed where it counted the most. Pigs exposed to the farm's virus pro...
Duke to test bird flu vaccine dosing
...of the Duke study. "If the smaller dose stimulates immunity
against the virus, then more people could be immunized with existing supplies if a pandemic occurs," he said. The study will use an inactivated flu virus vaccine based on a strain taken from a Vietnamese patient in 2004. "There is no live flu virus i...
UCR-led study identifies crucial mechanism involved in immune response against viruses
...y can serve as an excellent model for studying the immunity
animals are born with for fighting viral infection...nown among scientists about the fruit fly's innate immunity
it is born with against bacterial and fungal pathogens, but little is known about the...
International award honors discoveries in cellular and molecular immunology
...cidated the critical functions of these factors in immunity
and oncogenesis. Prior to joining the medical faculty at the University of Tokyo in 1995, Taniguchi was a professor at the Institute for Molecular and Cellular Biology at Osaka University, and held positions of escalating importance with the Cancer I...
For the first time: Longevity modulated without disrupting life-sustaining function
... and youthfulness -- without disrupting fertility, immunity
or the organism's response to stress. "In past experiments, meddling with this versatile pathway to exploit its beneficial effects on aging and life span inevitably invited a host of problems," says Andrew Dillin, Ph.D., an assistant professor in the...
JCI table of contents: March 1, 2006
...egulatory role for the C5a anaphylatoxin in type 2 immunity
in asthma AUTHOR CONTACT: Jrg Khl Cincinnati Children's Hospital Research Foundation, Cincinnati, Ohio, USA Phone: (513) 636-1219; Fax: (513) 636-5355; E-mail: firstname.lastname@example.org View the PDF of this article at: https://www.the-jci.org/articl...
Newly identified mechanism helps explain why people of African descent are more vulnerable to TB
...acillus has remained an additional puzzle. Innate immunity
is the rapid immune response of host scavenger cel...r. "This study provides a new mechanism for innate immunity
in humans and demonstrates how variations in vitamin D synthesis may make individuals susceptible to...
New influenza vaccine takes weeks to mass produce
...ccines produced using this system are safe, elicit immunity
equal to or greater than egg-based vaccines, and are 100% effective in the prevention of cell culture confirmed influenza. Wang and his colleagues report the successful production of rHA from 4 strains of influenza that scientists believe to be like...
Genomics-based vaccine could prevent deadly cattle disease
...tial vaccine proteins. First, scientists know that immunity
to the parasite, and thus East Coast fever, emerges from immune system cells known as killer T cells. Second, they know that T. parva is an intracellular pathogen--it infects and secretes proteins inside cattle white blood cells, which become malig...
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