Tag: "immunotherapy" at biology news
UCLA scientists uncork fountain of youth for HIV-fighting cells
...A team's approach could provide the foundation for immunotherapy
as a treatment for HIV and related diseases that rely on lasting protection by the same immune cells. These include cancer and latent cytomegalovirus, a viral infection that often strikes organ-transplant patients and persons with AIDS....
JCI table of contents, December 15 2004
...ies of Cd1d-dependent NK T cells in T cellmediated immunotherapy
AUTHOR CONTACT: Vincenzo Cerundolo Tumor Immunolog....org/cgi/content/full/114/12/1696 . Alternative immunotherapy
for prostate cancer bone lesions Prostate cancer (PC) is the most commonly diagnosed malignancy and...
US researchers uncover the science behind the breast cancer protective effect of olive oil
...eu synergistically interacted with Herceptin-based immunotherapy
by promoting the death of breast cancer cells exhibiting high levels of the oncogene. "Additionally, alongside the sensitising effect of oleic acid on the efficacy of Herceptin we found it increased the expression of a protein (p27Kip1), a tum...
Immune cells become potent cancer killers after genetic redirection
...vide the basis for development of a new, extensive immunotherapy
for human tumors. Normal cells that have transform...ation of this approach for a novel, broad-spectrum immunotherapy
of malignant disease."...
Source of molecular triggers in cutaneous T cell lymphoma identified
...ting Treg-cell generation may be useful for cancer immunotherapy
and promoting Treg development may be useful to induce tolerance in autoimmune disease and transplantation,"...
Hopeful results from interrupted Alzheimer's vaccine study
... phase II clinical trial to test a new Alzheimer's immunotherapy
vaccine strategy that has been through a phase I safety trial. The phase II study, which aims to stimulate an immune attack against beta amyloid without raising brain inflammation risk, is being conducted at 30 centers in the United States and dosing...
UCLA cancer researchers shake loose hidden biomarker
...utics, could have important implications for using immunotherapy
to treat prostate cancer, said Ayyappan K. Rajasek...membrane, which blood can't reach, so injection of immunotherapy
into the bloodstream is not effective," said Rajasekaran, also an associate professor of pathology a...
Optimizing cell therapy against tumors is a balancing ACT
...are important for development of improved adoptive immunotherapy
approaches for treating tumors and established infectious diseases....
JCI table of contents June 1, 2005
...are important for development of improved adoptive immunotherapy
approaches for treating tumors and established infectious diseases. TITLE: Acquisition of full effector function in vitro paradoxically impairs the in vivo anti-tumor efficacy of adoptively transferred CD8+ T cells AUTHOR CONTACT: Nicholas P. Restif...
U. Iowa finding speeds up immunization booster schedule
... shots. The finding has important implications for immunotherapy
-- using vaccines to treat cancer -- where developing immunity fast is critical. In the UI study, mice treated with a dendritic cell vaccine and a booster shot were protected against a bacterial infection in a matter of days compared to the several w...
Researchers find potential Celebrex target in lung cancer
...-2 inhibitors could be given with chemotherapy and immunotherapy
drugs to help boost immune function in patients and help them to better fight cancer, Dubinett said. Dubinett and his research team had hypothesized that PGE2 might be involved in suppression of the immune system. They first tested the theory in ani...
Newfound roadblock to interferon effectiveness against malignant melanoma
... use of interferon has become the most established immunotherapy
for advanced-stage melanoma. However, melanoma tumors often develop a resistance to the drug, posing one of the major obstacles in the clinical treatment of this cancer. Now Professor Manfred Schartl and Dr. Claudia Wellbrock, scientists at the Unive...
Researchers seeking alternative to surgery for brain cancers
...nois at Urbana-Champaign are working to develop an immunotherapy
that would be a safe alternative to surgery for brain cancers. Current treatments of surgery, radiation and chemotherapy often provide only marginal survival benefits and sometimes leave patients, especially children, with losses of cognitive functio...
Rare immune cell is key to transplant's cancer-killing effect
...ret weapon behind the most powerful form of cancer immunotherapy
known to medicine. Scientists call it the graft-v...s significant, because it could help make cellular immunotherapy
safer, more effective and an option for more cancer patients especially those for whom a donor is u...
Researchers use 'trickery' to create immune response against melanoma
PITTSBURGH, Nov. 1 A new type of immunotherapy
in which dendritic cells are tricked into action a...ers describe the creation of an animal model of an immunotherapy
approach that, first used in cancer patients, uses a patient's own tumor cells to stimulate anti-tum...
New treatment options for patients with prostate cancer
... bicalutamide therapy." In an ongoing study, a new immunotherapy
product, APC8015, is currently under investigation...hese trials of APC8015 versus placebo suggest that immunotherapy
might impact survival in men with androgen independent prostate cancer. APC8015 has a favorable saf...
New ECCO studies highlight promising potential of cancer immunotherapy
...highlighted the important therapeutic potential of immunotherapy
in the treatment of a number of different cancers e.g. for treatment of renal and skin cancers. Renal cancer is the 6th leading cause of cancer death with a survival rate of 11% for stage-IV disease. More than a million skin cancer cases occur each y...
UCLA researchers observe how the immune system recognizes and responds to cancer
...e response. "Many of the problems in evaluating immunotherapy
protocols stem from the lack of effective tools to follow the extent and duration of responses to treatment," the study states. "In this study, we have demonstrated a strategy to monitor a specific primary immune response against a tumor challenge."...
Biovest International announces that it will report new follow-up data
...Hodgkin's lymphoma are being treated with BiovaxID immunotherapy
following PACE [Prednisone, Doxorubicin, Cyclophosphamide, and Etoposide (ProMACE without methotrexate)] chemotherapy. At the meeting of the American Society for Hematology, Biovest will provide an update on patients who were treated with BiovaxID i...
Source of crucial immune cell in the skin discovered
...ineer immune responses in vaccine design and tumor immunotherapy
and to a better understanding of the immune response against skin pathogens." "Now that we know which cells are the precursors to Langerhans cells and the importance of Csf-1, we may be able to enhance tumor vaccines by increasing the recruitment of ...