Tag: "impaired" at biology news
Is Interleukin-6 the 'holy grail' of exercise mediation?
...tant skeletal muscle in an attempt to overcome the impaired
glucose uptake. And in other contexts, the current thinking is that IL-6 has primarily anti-inflammatory effects. It is this combination of effects that has prompted such widespread study....
Brain circuit may permit scientists to eavesdrop on memory formation
... result," said Schuman. "Either we had selectively impaired
the process of converting short-term memories into long-term memories. Or, short-term and long-term memories are on parallel pathways, and the lesion had selectively affected the long-term memory pathway." So, in a second set of experiments, the rese...
New genetic tools provide clues to the effects of exercise and diet on obesity, diabetes
... benefits of habitual exercise in individuals with impaired
glucose tolerance." ...
Biological importance of basal activity of appetite suppressor
... a cluster of mutations at the N-terminal end that impaired
the constitutive activ-ity of MC4R. Deletion of the N-ter-minal portion of the protein demonstrated that it is required for this basal activity. Further analysis proved that this domain func-tions as an intermolecular self-activating ligand that does...
Expert panel offers prelimary report on health effects of assisted reproductive technologies
...rt increased risk of most malformations, cancer or impaired
psychosocial development. However, singleton IVF babies are at increased risk for low birth weight, prematurity and perinatal mortality. There is a tenfold increase in multiple births following IVF compared to the overall population (32 percent...
Study is looking at ways to help stroke survivors regain lost motor skills
...hat study participants stroke survivors suffering impaired
hand or arm movement who underwent physical rehab...ing a new area of the brain to take over functions impaired
by stroke damage. In the study, surgeons place a set of small stimulating electrodes on the pro...
Newly discovered protein suggests novel tumorigenic pathway
...ined that this discovery indicates that cells with impaired
PICT-1 function may become cancerous because of the resulting instability in PTEN. This would represent a new tumorigenic pathway that is not due to a defective PTEN gene but rather a loss of PTEN function caused by PICT-1. If this is the case, the...
Researchers discover gene mutations for Parkinson's disease
...ease occurs when certain nerve cells die or become impaired
and can no longer produce dopamine. Without it, in... slowness of movement; and postural instability or impaired
balance and coordination. Patients may also have difficulty walking, talking, or completing other si...
Reductions in blood oxygen levels in newborns could contribute to ADHD development
...ess and distractibility, reduced self control, and impaired
learning, which are hallmark traits associated wit...window of brain development, the hyperactivity and impaired
learning that also occur are not noticeable until later, when juvenile animals are old enough to dis...
Deciphering an autism mystery
... thought to control many of the functions that are impaired
in autistic children, such as language and attention span," Millonig says. Their next clue came from studies of mutant mice. Mice with a mutation in the ENGRAILED 2 (EN2) gene also have a smaller cerebellum. And while scientists had not yet pi...
Early life stress harms mental function and immune system in later years
...abuse during infancy may result in memory loss and impaired
cognitive abilities that manifest later in life, a University of California , Irvine, study has found. The study, conducted in rats, clearly shows a late onset and slow progression of deficits in communication between brain cells in the hippocampus, ...
Yerkes researchers to present array of new data at Society for Neuroscience Meeting
...asive, infrared, eye-tracking technology to detect impaired
memory in humans before major damage occurs in the brain. This finding could lead to the development of early intervention therapy to stop or slow the progression of Alzheimer's disease. (6 p.m. 7 p.m.)...
Is the zebra fish leading us to new therapies?
...oning body. Disorders in which the blood supply is impaired
are quite serious: deficient blood supply to the heart, for example, leads to heart attack. Medical science hopes to be able to treat such diseases in the future by stimulating the growth of new blood vessels, a form of therapy called therapeutic ang...
Stress impairs thinking via mania-linked enzyme
...s, an animal study shows. The disturbed thinking, impaired
judgment, impulsivity, and distractibility seen in... direct or indirect activation of PKC dramatically impaired
the cognitive functions of the prefrontal cortex, a higher brain region that allows us to appropriat...
Fat buildup found in hearts of obese or diabetic heart failure patients
...displace its contractile proteins, that results in impaired
heart function." Taegtmeyer and colleagues are testing this hypothesis among obese patients who have elected to have bariatric surgery (surgical reduction of stomach size). Patients in the study volunteer to have their cardiac function analyzed and ...
Sleeping, waking, ... and glucose homeostasis
...ly treated with insulin, this ability was severely impaired
in the mutant mice. What's more, a high-fat diet amplified this circadian variation in the normal animals, but the rhythm was abolished in the mutants on a high-fat diet. Thus, the authors demonstrated that circadian control of blood glucose levels i...
Researchers discover transport molecule that allows boron into cells
... is clear. Numerous birth defects occur, including impaired
growth and missing or extra limbs. Many animals cannot survive in the complete absence of boron. On the other hand, like many vitamins and minerals, too much is as bad as not enough. High levels of boron are toxic. Dr. Muallem's group showed that...
No getting around RET
...ed in size in NCAM-deficient mice as the result of impaired
migration of neural precursors through a zone called the rostral migratory stream and swell with cells that have failed to reach their normal destination; this phenotype is seen in mice only weakly lacking GFR1 (which is thought by some to regulate N...
Study: Pigeons can sense the Earth's magnetic field; ability might allow them to return home
...ring the ophthalmic branch of the trigeminal nerve impaired
the birds' ability to detect magnetic fields, whil...he pigeons learned to perform in the laboratory is impaired
by various treatments, we can now say that the pigeon's magnetic sense is located in the nasal regio...
Psychological stress and disease: UCSF-led study suggests connection
...etween chronic psychological stress and indices of impaired
health, including cardiovascular disease and weakened immune function," says lead author Elissa Epel, PhD, UCSF assistant professor of psychiatry. "The new findings suggest a cellular mechanism for how chronic stress may cause premature onset of dise...
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