Popular herbal supplement hinders the growth of pancreatic cancer cells
...ent or slow the growth of pancreatic cancer tumors implanted in mice. The study found that an extract of triphala, the dried and powdered fruits of three plants, caused pancreatic cancer cells to die through a process called apoptosis the bodys normal method of disposing of damaged, unwanted or unneeded cells...A genetic 'gang of 4' drives spread of breast cancer
Studies of human tumor cells implanted in mice have shown that the abnormal activation of four genes drives the spread of breast cancer to the lungs. The new studies by Howard Hughes Medical Institute researchers reveal that the aberrant genes work together to promote the growth of primar...The sturdier sex? -- Study by Pittsburgh scientists finds female stem cells work better
...onor cells. Only one of the 10 male populations of implanted stem cells had an RI over 200. In contrast, 40 percent of the female stem cell populations had an RI higher than 200, and 60 percent of the female populations of stem cells had an RI higher than the mean RI of the male cells (95). This difference m...Want to monitor climate change? P-p-p-pick up a penguin!
...lationships between these two variables. They then implanted heart rate loggers in penguins going to sea such that they could infer the energy expended by these birds from the recorded heart rate. Researchers were then able to find out if there was a correlation between the energetic costs of foraging at sea a...Engineering the heart piece by piece
...roducts of this tissue engineering are ready to be implanted in patients as replacements for diseased or malformed structures, the team notes. Among the hurdles: determining which types of cells hold the most potential, and finding the best way to grow those cells to form viable cardiac tissue that is strong, ...MIT: Pulsing light silences overactive neurons
...ratically," he said. Many epilepsy patients have implanted electrodes that periodically give their brains an electric jolt, acting as a defibrillator to shut down overactive neurons. This new research opens up the possibility of an optical implant that could do the same thing, using light instead of electric...DNA layer reduces risk of reserve parts being rejected
...-operative adhesions, and in biosensors such as an implanted glucose sensor for diabetic patients. ...Natural polyester makes new sutures stronger, safer
...hat could be used to grow heart valves after being implanted in a patient, which would spare children with heart valve defects from undergoing repeated surgeries. Tests of the device in animals have shown promise. "We've been able to show we can produce a valve scaffold that functions better and can grow wit...Chemical cues turn embryonic stem cells into cerebellar neurons
...versity scientists shows that embryonic stem cells implanted in the brain appear to develop into fully differen... new study in mice shows that embryonic stem cells implanted in the brain appear to develop into fully differentiated granule neurons, the most plentiful neurons...Stem cells act through multiple mechanisms to benefit mice with neurodegenerative disease
... related to Tay-SachsDisease. When stem cells were implanted -- at simply one time point --into brains of newbo... >70%. The researchers discovered that their implanted neural stem cells, whichmigrated and integrated extensively throughout the brain, did much morethan ...Light-activated compound silences nerves, may one day help epileptics
...ut we might one day combine this drug with a small implanted light to stop seizures," says senior author Steven Mennerick, Ph.D. associate professor of psychiatry and of anatomy and neurobiology. "Some current experimental epilepsy treatments involve the implanting of an electrode, so why not a light?" The ne...ACS News Service Weekly PressPac -- Feb. 21, 2007
...nd, FR901464, inhibited the growth of cancer cells implanted into laboratory mice. Because of structural similarity between FR901464 and their analogue, called meayamycin, the Koide group is cautiously optimistic that meayamycin also will be effective against tumors in mice. The amount that the Koide employed ...BC biologists identify alternative brain cancer treatment
...not. In their experiment, the BC team surgically implanted two different kinds of tumors into the brains of male mice. The mice were then divided into three groups. One group was fed a high-carbohydrate mouse chow, one was given unlimited amounts of KetoCal, and the final group was given KetoCal in a restric...UCI awarded $3.5 million for stem cell research
...f tumor growth when human embryonic stem cells are implanted into healthy tissue or when tissue is compromised by irradiation. Understanding the cancer risks associated with the therapeutic use of human embryonic stem cells is poorly understood and critical for the field to move forward. Thomas Lane, profess......ells. At this point, the cultured blastocysts were implanted in a mouse's uterus and allowed to develop into a cloned fetus. This is the cloning technique known as nuclear transfer. Typically, only about one to two percent of transferred mouse blastocysts result in a live birth. Furthermore, cloned mice that...Woven scaffolds could improve cartilage repair
...hs to grow a piece of cartilage large enough to be implanted back into the patient. Additionally, this laboratory-grown cartilage is not as durable as native cartilage. In laboratory tests, the fabric scaffold that the researchers have created had the same mechanical properties as native cartilage. In the ne...Sea creature's toxin could lead to promising cancer treatment
...a synthetic form of the toxin reduced human tumors implanted in mice without the harmful side effects seen using other cancer drugs. "Diazonamide is a special molecule it's teaching us more than we imagined," said Dr. Patrick Harran, professor of biochemistry and a senior author on both studies. "This is a ...Scientists identify pancreatic cancer stem cells
...stem cells in pancreatic cancer, the research team implanted cancerous tissue from human pancreatic specimens r...ersity School of Medicine. The researchers then implanted about 100 of each type of cell in mice, and found that tumors would grow in a subset of the animals,...U-M researchers identify stem cells in pancreatic cancer
...th pancreatic cancer. The samples were divided and implanted into mice to grow new tumors, allowing a larger sample to be studied. The researchers sorted the tumor cells based on whether they expressed certain antibody markers on the cell surface, specifically CD44, CD24 and epithelial-specific antigen, or ESA...Huddling and a drop in metabolism allow penguins to survive the South Pole cold
...throughout their breeding cycle by using long-term implanted data loggers. The researchers sought to assess wh... devices during pairing and visual observations of implanted males during incubation, they sought to study deep body temperature variations when the birds were h...