Tag: "implicated" at biology news

Rats infected as newborns grew up vulnerable to memory problems during an immune challenge

...s. For example, prenatal viral infection has been implicated in schizophrenia, autism and cerebral palsy; bacterial infection is a risk factor for Parkinson's disease. Up to 20 percent of pregnancies have complications involving infections of the uterus and its contents, a number that will rise as more childr...

Rat brain's executive hub quells alarm center if stress is controllable

...f control over stressful life experiences has been implicated in mood and anxiety disorders. Rats exposed to unc...f a brainstem area (dorsal raphe nucleus) has been implicated in such reactions. But this area is too small and lacks the proper sensory inputs to judge whether a...

Researchers turn to brainpower to beat dementia

...ur and susceptibility to disease and, of the genes implicated in intelligence, the associated polymorphism has been shown to alter the function of the gene." Theoretically, the research with Mensa will be the most powerful approach to studies in this field ever adopted. The study of 2,500 elderly people over 20...

Critical role in programmed cell death identified

...g and targeting a process vital to development and implicated in cancer and autoimmune diseases. The work, re...other complications. "Mammalian studies that have implicated mitochondrial fragmentation in cell death have been done under rather artificial conditions, in tiss...

Inherited gene may increase risk for prostate cancer by 50%

...It has since been discovered that KLF6 defects are implicated in a number of other human cancers, including colorectal, lung and liver. The variant of the gene investigated in the report published this week produces a an altered version of the KLF6 protein. Rather than entering the cell nucleus to suppress cel...

Researchers identify target for cancer drugs

...l. Abnormally high activation of Akt has long been implicated in a variety of cancers. If Akt travels to the cell membrane, it is switched on and promotes cell division, often contributing to tumor growth as a result. However, as long as it stays within the cell cytoplasm, it remains relatively inactive. That's...

Coastal dead zones may lead to ecosystem-based fisheries management

...sized fish. Such zones in the Neuse have also been implicated in fish kills when wind conditions and currents conspire to trap the fish on the bottom in a way that makes it hard for them to escape the low-oxygen waters, he added. In the Gulf, "to date no one has been able to make a link between the dead zone an...

Genome-wide mouse study yields link to human leukemia

...or suppressor gene and a unique chemical signature implicated in the development of human leukemia, findings that open up a "treasure box" of opportunity and possibility, study authors say. Researchers in The Ohio State University Comprehensive Cancer Center bred a type of mouse that develops acute lymphoblast...

Tailing the cause of a rare heart disease

...s, said Christine Seidman. "The EYA4 gene had been implicated in hearing loss before, but in none of the patients where mutations had been characterized had there ever been an abnormality of the heart reported," she said. The Seidmans also found that the gene was expressed in adult heart tissues, which is unusu...

Olfactory receptor cells may provide clues to psychiatric disease

...erly-functioning nerves, and previous studies have implicated dysfunctions of cellular calcium metabolism as a contributing factor to bipolar disorder. Changes in how much calcium is inside ORNs and other nerve cells tell researchers how the nerves respond to stimulation. In the study, researchers used a flu...

Norovirus found to cause traveler's diarrhea

... Norovirus. Although Norovirus previously has been implicated as a cause of traveler's diarrhea among visitors to Mexico, this is the first study to indicate that Norovirus contributes to traveler's diarrhea in visitors to Guatemala. Amy R. Chapin, first author of the study and a PhD-candidate in the Departmen...

Gene variation could be responsible for age-related macular degeneration

...t-ahead vision. "We've identified a gene that is implicated in the pathogenesis of AMD," said Robert Ritter, a UT Southwestern research scientist involved in the Science study. "It provides a starting point for future investigations that will help us understand what takes place during the breakdown of the vis...

Silence the gene, save the cell: RNA interference as promising therapy for ALS

...gene expression in neighboring glial cells is also implicated in motor neuron death. Lead author Cedric Raoul and colleagues targeted the cause of the disease by using RNA interference to silence the defective gene, preventing it from expressing the SOD1 protein. RNA interference is part of a complex cellular ...

Researchers rein in regulatory RNAs

...least 8% of human genes. Many SAT pairs have been implicated in various stages of gene regulation, including transcription, mRNA processing, splicing, stability, transport, and translation. Various examples of such overlapping genes have been documented in all life forms from viruses and prokaryotes to plant...

Tumor individuality useful for guiding rational chemotherapeutic decisions

.... The researchers examined BIM because it has been implicated as a tumor suppressor and is known to play a role in the regulation of apoptosis. The researchers found that BIM accumulation is absolutely required for paclitaxel-induced apoptosis, and that BIM deficiency is associated with paclitaxel-resistant tum...

Childhood deficits in the cerebellum may be linked to adult alcoholism

...derly. A relatively new line of research has also implicated the cerebellar vermis the midline portion of the cerebellum in the regulation of behavior." "Only recently has the cerebellum's potential involvement in any psychopathology been considered," added Barry Liskow, professor of psychiatry and behavior...

Leptin: A 'missing link' between obesity and diabetes?

.... This was the first time that STAT3 signaling was implicated in obesity. The mice are so-called "knock-in" mice, because the scientists had introduced a gene mutation that interfered with the ability of the leptin receptor to initiate STAT3 signals after leptin had bound to the receptor. The other mice used i...

Study of genomic DNA leads to new advances in cancer diagnostics

...s sensitive or resistant to Alu I. The group also implicated the cell's cytoskeleton, the internal scaffolding that gives the cell its shape, in this process. Changes to the ECM and cytoskeleton are critical to migration of a cancer cell from one site in the body to another. The researchers could alter the ...

NASA study finds soot may be changing the Arctic environment

...nd the effects of pollution. Black carbon has been implicated as playing a role in melting ice and snow. When soot falls on ice, it darkens the surface and accelerates melting by increasing absorbed sunlight. Airborne soot also warms the air and affects weather patterns and clouds. Koch and Hansen?s results s...

Gene variations explain drug dose required to control seizures

...f both carbamazepine and phenytoin. SCN1A has been implicated in many inherited forms of epilepsy and is the drug target for phenytoin. Given its relationship to both anti-epileptic drugs tested, the SCN1A variant may be of particular importance for understanding patient response to drug treatment, said the res...

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(Date:8/27/2014)... of fish began exploring land and evolved into tetrapods ... ancient fish used their fishy bodies and fins in a ... scientific mysteries. , Researchers at McGill University published in ... called Polypterus , to help show what might have ... water. Polypterus is an African fish that can ...
(Date:8/27/2014)... when it only requires nerve cells to rearrange existing ... to generate new patterns, a study of monkeys has ... through recordings of electrical activity of brain cell networks. ... of Health. , "We looked into the brain and ... outside the box," said Aaron Batista, Ph.D., an assistant ...
(Date:8/27/2014)... manipulating neural circuits in the brain of mice, ... memories. The research, led by Howard Hughes Medical ... of Technology (MIT), reveals that the connections between ... information about an experience and the part of ... that experience are malleable. , Altering those ...
Breaking Biology News(10 mins):Walking fish reveal how our ancestors evolved onto land 2Scientists plug into a learning brain 2Scientists plug into a learning brain 3Researchers change the emotional association of memories 2Researchers change the emotional association of memories 3Researchers change the emotional association of memories 4
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