Tag: "imprinting" at biology news
For yeast, a DNA break ensures sex switch for a grandchild
...r Institute in Paris, France, has identified a new imprinting
mechanism that controls sexual switching in yeast....opose that this represents the first example of an imprinting
event that is due to a simple single-strand break. The discovery has general implications for how DN...
Chicken genomic sequence yields insight into vertebrate evolution
... interesting biological mechanism namely, genomic imprinting
appears to be restricted to more evolutionary adv...l of DNA by specific regulatory sequences known as imprinting
control elements. Although scientists have identified many of these imprinting
control motifs in ma...
Solving the mechanism of Rett Syndrome
...e Rett Syndrome is that the mutation disrupts this imprinting
mechanism. An imprinted gene, one with ... "Loss of silent chromatin looping and impaired imprinting
of DLX5 in Rett syndrome," by Shin-ichi Horike, Shutao Cai, Masaru Miyano, Jan-Fang Chen, and Terumi...
Scientists find impaired chromatin structure formation & imprinted gene involvement in Rett Syndrome
...n." "Loss of silent chromatin looping and impaired imprinting
of DLX5 in Rett syndrome," by Shin-ichi Horike, Shutao Cai, Masaru Miyano, Jan-Fang Chen, and Terumi Kohwi-Shigematsu, appears in the January issue of Nature Genetics . The paper is available online at http://www.nature.com/cgi-taf/dynapage.taf?fil...
It's not all genetic: Common epigenetic problem doubles cancer risk in mice
... have already noted an association between loss of imprinting
of IGF2 and colon cancer in people, the current ex...ents were designed to find out whether the loss of imprinting
is involved in cancer's development or just in its progression. "Most researchers, including me, ex...
Imprinting disorders and ART world's largest study results are reassuring
...rders known to be associated with aberrant genomic imprinting
patterns. Genetic imprinting
is a mechanism in which gene expression depends upon parental origin. Mutations can alter normal im...
Chickens orient using a magnetic compass
... chicks to find an object that was associated with imprinting
and was behind one of four screens placed in the c...ection of movement during searching for the hidden imprinting
stimulus was influenced by shifting the magnetic field. One important difference between this work a...
Blood test for colon cancer risk to be goal of Hopkins project
...m called loss of imprinting. To check for loss of imprinting
in people, the researchers will be looking for small methyl groups that should be attached to the DNA near the IGF-2 gene in blood cells from study participants. If neither gene copy has these methyl groups, both will be turned on, resulting in loss ...
The role of evolutionary genomics in the development of autism
...he fact that there is known to be a strong genomic imprinting
component to the genetic and developmental mechanisms of autism and autistic syndromes. Professor Bernard Crespi from Simon Fraser University, Canada explains: "The imprinted brain hypothesis underscores the viewpoint that the autism spectrum represe...
Non-coding RNAs help silence the mammalian transcription
...Kcnq1ot1. "As we explore the mechanism of genomic imprinting
in greater detail, it is becoming clear that there...hanisms lends further support to the argument that imprinting
arose gradually over a long period in mammals, not all at once," explains Dr. Tilghman....
Zebra finch males prefer females with exaggerated maternal traits
...unfamiliar one, it has generally been assumed that imprinting
itself could not give rise to preferences for nove...nt stimuli, but the presence of this effect in the imprinting
process has not been demonstrated previously. The outcome of the study shows that the skewed mating ...
How IVF could be causing genetic errors in embryos
...onday) that preliminary work investigating genetic imprinting
in mouse embryos had shown that certain culture me...nd why these techniques appear to be affecting the imprinting
of these genes. We hope this understanding will enable the scientific community to make better cultu...
Parental genes do what's best for baby
... But some genes through a process called genomic imprinting
only use one parents copy; the spare copy from th... is silenced by a chemical stamp. The concept of imprinting
has long puzzled scientists as it appears to undermine the natural benefits organisms gain from inhe...
Inheritance outside DNA
...the heart of the mystery of stem cells. Genomic imprinting
is a type of epigenetic change that causes one cop...of the general populationthat involves the loss of imprinting
on an insulin-like growth factor gene called IGF2. Loss of imprinting
of IGF2 has been associated st...
There's no scent like home
...n to the reefs where they were born. The olfactory imprinting
of natal reefs sheds light on how such a wide diversity of species arose. The homing behavior of reef fishes, the researchers contend, could support population isolation and genetic divergence that may ultimately lead to the formation of new species...
New hope for regenerative medicine
...e parental origin. Uniparental cells only have the imprinting
marks for one parental type (or "from one parent") with unknown consequences if harvested and transplanted into adults. Previous work has shown that uniparental ES cells have only limited ability to contribute to fetal and postnatal development in...
Penn researchers replace organ in adult mice using 'single-parent' stem cells
...ing," McLaughlin said. "It turns out that genomic imprinting
may be more a concern for developing stages and not so much a factor in the routine function of adult tissue, which was the ultimate goal for deriving these stem cells." To study uniparental stem cells and the possible effects of genomic imprinting...
Daddies' girls choose men just like their fathers
...e. It adds to growing theories that suggest sexual imprinting
is an active process which involves the relationship between the child and the adult upon whom they imprint. This reveals the importance of parental relationships in partner selection, which could move studies in areas like evolutionary biology, fert...
Other highlights in the Aug. 7 JNCI
...on epigenetic change in Wilms tumor is the loss of imprinting
of the IGF2 gene. In this case, loss of imprinting
means the copy of IGF2 that you get from your mother (which is usually turned off) is activated. Thi...