Interaction of just 2 genes governs coloration patterns in mice
...werful opportunity for natural selection to evolve increased camouflage. Through a detailed genomic analysis, Hoekstra, Steiner, and Weber identified two pigmentation genes, for the melanocortin-1 receptor (Mc1r) and an agouti signaling protein (Agouti) that binds to this receptor and turns it off. A single ...Green tea boosts production of detox enzymes, rendering cancerous chemicals harmless
... between deficient expression of these enzymes and increased risk of developing some cancers, Chow said. Expression of this enzyme varies dramatically in people due to genetic variation and environmental factors, Chow added. Green tea catechins somehow increase gene expression of these enzymes, which can be...Abnormal fat metabolism underlies heart problems in diabetic patients
...logy of shotgun lipidomics, we have identified the increased activation of certain lipid-digesting enzymes and the decrease of cardiolipin as central aspects of this disorder. We hope that these kinds of studies will enable physicians to diagnose diabetic cardiovascular disease sooner and treat it earlier."...Rain forest protection works in Peru
...ent years, the rain forests have been experiencing increased human impacts, as they have in neighboring Amazon countries, but the extent of the damage over the region has not been thoroughly assessed using high spatial resolution satellite data until this study. The scientists used the Carnegie Landsat Anal...Climate change and permafrost thaw alter greenhouse gas emissions in northern wetlands
... seems the permafrost degradation initially causes increased soil carbon sequestration, rather than the large releases of carbon to the atmosphere originally predicted. But over time high methane emissions will balance or outweigh the reduction of carbon in the atmosphere. Not all ecosystems underlain by ...Genetic variation helps to understand predisposition to schizophrenia
...hat one of these DNA variations is associated with increased expression of a novel type of Neuregulin 1 called type 4 one of the six known types of Neuregulin 1 proteins in the brains of patients with schizophrenia. The role of this protein in the brain is not completely understood but the other types of N...Research shows skeleton to be endocrine organ
...lcin protein showed that they had type 2 diabetes, increased fat mass, a decrease in insulin and adiponectin expression, and decreased beta-cell proliferation. This research was supported by the National Institutes of Health, the American Diabetes Association, the Japan Society for the Promotion of Science,...New molecular regulators of hyperthyroidism and goiter
...hormone (TSH). Increased levels of TSH, as well as increased signaling through the receptor for TSH, result in ...fit for individuals with diseases characterized by increased thyroid gland function and/or growth....JCI table of contents: Aug. 9, 2007
...hormone (TSH). Increased levels of TSH, as well as increased signaling through the receptor for TSH, result in ...fit for individuals with diseases characterized by increased thyroid gland function and/or growth. TITLE: Thyrocyte-specific Gq/G11 deficiency impairs thyroid ...Brain blood flow gives clues to treating depression
...d flow, he said. We found that cerebral blood flow increased only in patients whose depression improved. In contrast, cerebral blood flow remained unchanged in patients whose depressed condition persisted, detailed Bonne. Depression is a serious and debilitatingyet treatabledisease that affects every aspect ...Acute sleep deprivation leads to changes in nighttime urine production for men and women
...teers and have found that a lack of sleep leads to increased urinary output and more salt in urine. The finding...httime, acute sleep deprivation leads to: an increased urine output more evident in males a reduced fall in blood pressure (reduced nighttime dip) ...Study suggests estrogen deficiency can lead to obesity-induced high blood pressure after menopause
...ndergo any of the changes mentioned above. With increased life expectancy, women spend more than a third of their life in menopause. In addition, obesity is increasing dramatically in all populations and is a major cardiovascular risk factor in women after menopause. Despite the controversial data about est...Testosterone replacement therapy: How safe for aging men?
...was nearly 819,000, and the number is growing. The increased use has occurred despite the fact that the cardiovascular effects of chronic testosterone treatment in aging males are largely unknown, and the safety of testosterone replacement has not been evaluated. A team of researchers has been using an anim...Weizmann Institute scientists discover a control mechanism for metastasis
...r place, while overproduction of this protein plug increased their migration. Next, the scientists carried out tests on tumor samples taken from around 300 patients with inflammatory breast cancer, a rare but swift and deadly form of the disease, which is associated with elevated growth factor levels. The s...News tips from the Journal of Neuroscience
...rats intrathecally with the C5a anaphylatoxin. C5a increased cold pain sensitivity, and a C5a receptor antagonist blocked this effect, consistent with a role for C5a in neuropathic pain....Preclinical study links gene to brain aneurysm formation
...changes in blood flow. When a vessel experiences increased blood flow, it attempts to reduce the shear stress... it links a known gene with a known function to an increased risk for intracranial aneurysm formation. Abruzzo says this study supports the idea that the NOS-......eria-free and that bacteria counts in normal flies increased dramatically as the flies got older. But all the flies lived about as long approximately three months....Link between sunspots, rain helps predict disease in east Africa
...reasons why sunspot peaks may affect rainfall. The increased solar energy associated with sunspots, they suggest, heats both land and sea, forcing moist air to rise and triggering precipitation. It may also induce El Nio events, which increase rainfall in East Africa. While sunspot peaks augur extraordinaril...Cornell scientists link E. coli bacteria to Crohn's disease
... genotype may improve outcome. The study found an increased level of E. coli bacteria in more inflamed areas of the small intestines instead of MAP, a bacterium related to tubercle bacillus that has been more commonly associated with Crohns....Study: Sticking to the sand might not be such good, clean fun for beachgoers
...health advisories throughout the United States has increased steadily, according to the NRDC. In 2005, the coun...sand decreased, while its presence in the seawater increased after it flowed through the sand samples. The team then returned to Lovers Point to research the m...