Pre-clinical study finds Parkinson's cell death blocked by stopping inflammatory factor
...enior author of the study. "Our prediction is that independent of the environmental toxin or trigger that induces... dopamine neuron loss might also involve processes independent of TNF. "If an intervention could still reduce the extent or rate of cell death by 50 percent, it...Craig Mello named winner of The Dr. Paul Janssen Award for Biomedical Research
...he Award recipients are chosen by a preeminent and independent selection committee composed of world-leading scientists and clinicians. Intending to acknowledge a scientist whose work has the potential to make a significant, transformational contribution toward the improvement of human health, the Award includes...Genomatix appoints distributor for the growing Chinese market
...ively to the Chinese government, ZGZ has become an independent entity last year. ZGZ is focusing on the research and development in biomedicine, new drug resources, biology information and biometrics research. Based on its rich experience and technological background, ZGZ is active in the international biochip...US clinical researchers resist full financial disclosure, according to Conflicts-of-Interest Study
...s were solicited from 40 academic medical centers, independent hospitals, independent institutional review boards, and unaffiliated research entities. The study is conducted by Duke Univ...OHSU lab links gene to aged skin problems, cancer
...ily skin. Surprising to the researchers was that, independent of its normal role in blocking signaling from a group of genes called Smad, Smad7 shuts down signaling of another group of genes called Wnt, by binding to a Wnt signaling protein known as Beta-catenin and degrading it with an enzyme called Smurf2. Wn...Genome code cracked for breast and colon cancers
...mmel Cancer Center. Although gene discoveries by independent scientists scattered around the world have provided clues, Velculescu says relatively few genes have been shown to be altered in cancers. The Hopkins gene hunters say the number of genes that were altered in breast and colorectal cancer genomes surp...Modern humans, not Neandertals, may be evolution's 'odd man out'
...areful to examine traits that appear to be largely independent of each other to avoid redundancy. "I wanted to see to what extent Neandertals are derived, that is distinct, from the ancestral form. I also wanted to see the extent to which modern humans are derived relative to the ancestral form," Trinkaus says...Study suggests a second dimension to Alzheimer's disease
...howed presenilin's role in calcium signaling to be independent of its role in the production of amyloid . The findings suggest that drugs that restore normal calcium levels might be useful for treating Alzheimer's disease, Bezprozvanny said. Indeed, he added, a drug called memantine, which is already in use aga...Researchers identify neurons that assign value during learning
...versive values were assigned to neutral stimuli by independent sets of neurons. To tackle this question, the researchers engineered transgenic fruit flies that express in distinct nerve cells a special ion channel, "channelrhodopsin-2," whose activity is light-sensitive (the protein is normally found in green ...Breast density helps predict breast cancer risk
...s write, "If the new model is shown to be valid in independent evaluations, a more convenient program could be made available for counseling and other applications." In an accompanying editorial, Melissa L. Bondy, Ph.D., of the M.D. Anderson Cancer Center in Houston, and Lisa A. Newman, M.D., of the University ...Gene signature assesses breast cancer outcomes
...hese results indicate that the gene signature adds independent prognostic information to that provided by a risk assessment based solely on clinico-pathologic factors." In an accompanying editorial, Richard Simon, D.Sc., of the National Cancer Institute in Rockville, Md., discusses the strengths and limitations...Mother deer cannot recognize the calls of their own offspring but sheep and reindeer can
... mechanisms," says McElligott. "This appears to be independent of phylogenesis because although fallow deer and reindeer are more closely related than reindeer and sheep, the mother-offspring recognition system of reindeer and sheep is more similar."...JCI table of contents: September 1, 2006
... and bladder and bowel control is described in two independent papers to be published in the September issue of t...s of immune cell known as B cells and T cells. The independent development of this mouse model of NMO by Andreas Holz and colleagues from the Max Planck Institute ...Disabling a carbohydrate trigger reduces obesity and appetite
...bohydrate response element binding protein), quite independent of insulin, initiated a sequence responsible for converting excess carbohydrates to fatty acids for long-term storage. In a study that appears in this month's edition of the American Journal of Physiology-Endocrinology and Metabolism, the same labor...First human study confirms that immune cells can be a primary cause of bone loss in gum disease
...ed that any bacteria per se invade and resorb bone independent of osteoclast activation, RANKL expression by T cells and B cells proves to be one of the major stimuli of osteoclast precursor cells and, hence, bone loss through periodontal disease. ...Gene variants reveal susceptibility to cardiovascular disease
...ficant association of two of the same SNPs in this independent group of patients. This finding, according to the researchers, validated the suspected link between GATA2 and coronary artery disease. "A huge strength of our study is that we used two separate populations, finding the association between GATA2 and...First 'encyclopedia' of nuclear receptors reveals organisms' focus on sex, food
...o influence metabolism, rather than in a series of independent signaling pathways. "Understanding timing patterns of receptors might help explain aspects of the out-of-rhythm states linked to many metabolic diseases," Dr. Mangelsdorf said. Researchers detailed all receptor expression in the superfamily on a...Researchers identify the cells and receptor for sensing sour taste
...ng sweet, bitter, umami and sour, must function as independent sensors because the "sourless mice" have perfectly normal salt perception," he said. "So this opens an exciting experimental platform to molecularly dissect the last of the five basic taste qualities: salt taste."...UC Davis researchers move biotechnology closer to replacing electronic pacemakers
...er 5). The same issue also includes a similar but independent research effort by scientists from Columbia University and State University of New York at Stony Brook. "Our study offers positive and direct evidence in living models that bioengineered cells can replace the electronic pacemaker," said Ronald Li, ...Trap-jaw ants have fastest recorded strike in animal kingdom
...he system been used for propulsion. These multiple independent origins of such structures - a rare occurrence in evolution - offer insights into how novel behaviors may evolve in biology. The researchers used a high-speed video camera filming at 50,000 frames per second to visualize the mandible movements. The...