Tag: "inflammatory" at biology news
Omega-3 fatty acids affect risk of depression, inflammation
...ater risk for both clinical depression and certain inflammatory
diseases. The report, published online this week...tients with depression, cardiovascular disease and inflammatory
and autoimmune diseases. Martha Belury, an associate professor of human nutrition, endocrinology, ...
News tips from the Journal of Neuroscience
...opontin (OPN) is expressed by microglia as part of inflammatory
responses. Although suppression of OPN results in a better outcome in animal models of autoimmune disease, Hashimoto et al. report this week that OPN may be neuroprotective in spinal cord injury. The authors compared the effects of a spinal cord cont...
UBC researchers find new superbug weapon for near-empty antibiotics arsenal
...ptic response. Sepsis, a consequence of a ravaging inflammatory
response associated with infection, kills as many as 200,000 annually. The innate immune response is the first line of defense against infection and comprises an interactive network of cellular and molecular systems that recognize and kill pathoge...
Could estriol be the elixir for MS?
..."pretty remarkable" results an 80 percent drop in inflammatory
lesions in the brain, a hallmark of the disease. This month, Voskuhl begins a much larger trial of estriol, one that will involve 150 patients at multiple locations over the next two years. The prospects, she said, are exciting. Multiple scleros...
JCI table of contents: March 15, 2007
...e mobilization from bone marrow and recruitment to inflammatory
sites AUTHOR CONTACT: Israel F. Charo Gladstone Institute of Cardiovascular Disease, San Francisco, California, USA Phone: (415) 734-2000; Fax: (415) 355-0960; E-mail: firstname.lastname@example.org . View the PDF of this article at: https://www.the-...
Burroughs Wellcome fund awards $8.25 million in grants to physician-scientists
....D., Ph.D. Washington University Pathogenesis of inflammatory
Researchers identify molecular basis of inflammatory bowel disease
...ar mechanism that is likely to also underpin human inflammatory
bowel disease. Our gut is home to an enormous numb...leading to chronic inflammation as we know it from inflammatory
bowel diseases in humans." The finding that defective NF-kB signaling in the gut epithelium initiate...
Sphingolipids with therapeutic ends
...arge part of the population. There exist important inflammatory
reactions caused by sphingolipids. They are investigating the origin of the disease and the return of the altered tissues to their normal state. How is it being undertaken? The process being followed is, in general, as follows: the most impor...
JCI table of contents -- March 1, 2007
...ung modified by the oxidant that would initiate an inflammatory
reaction if not removed. A similar role in the rem...serine proteinase inhibitors, and many acute-phase inflammatory
proteins. By contrast, HDL from patients with CAD contained high levels of the protein apoE, which i...
Cells in the lung clear the air to prevent lung damage
...ung modified by the oxidant that would initiate an inflammatory
reaction if not removed. A similar role in the removal of lipids in the lung modified by these oxidants was identified for another protein related to MARCO, SR-AI/II. As discussed in an accompanying commentary by Edward Postlethwait from the Universi...
McGovern Institute Scolnick Prize awarded to David Julius
...ery of the molecular receptors for temperature and inflammatory
pain. David Julius has transformed our understanding of temperature perception and pain, says McGovern Institute director Robert Desimone. His work is of great importance for basic neuroscience and medicine, and we are very pleased to honor his g...
MIT bioengineer advances survival, promise of adult stem cells
...th and her clinical collaborators believe that the inflammatory
response following transplant may limit survival o...protected the cells from being killed by pro-death inflammatory
signals. The soluble version of the factor did not protect cells." So far all of the experiments h...
The metabolic response to colitis varies depending upon whether inflammation is chronic or acute
...s after resuming water-only consumption. The inflammatory
score and the levels of local pro-inflammatory mar...ared to controls. In addition, levels of systemic inflammatory
markers were elevated in mice with acute or chronic inflammation compared to controls. Metaboli...
New imaging technique tracks traffic patterns of white blood cells
...nteract specifically with neutrophils, a subset of inflammatory
white blood cells. "The ease and rapidity of this method, and the abilty to combine it with current genetic labeling techniques will greatly aid investigations to elucidate in vivo imflammatory cell behavior, and provide a powerful tool for the devel...
Experimental Biology 2007: Today's Research, Tomorrow's Health, April 28-May 2
...ase; roles of intestinal epithelia and bacteria in inflammatory
disease; and the potential benefits of suspended animation-like states in the mitigation of injuries that induce brain ischemia, including recent findings about novel chemical mediators that may be used to induce these protective conditions clinicall...
JCI table of contents -- February 22, 2006
...rs in Crohn disease) result in a localized chronic inflammatory
response that causes the formation of granulomas (...mice undergo HPC their lungs exhibit an attenuated inflammatory
response to severe hypoxia compared with mice that received no HPC. In particular, the expression of...
Newborns with respiratory distress potentially have rare genetic disease
...structed and infected, which incites a destructive inflammatory
process in those organs. Cilia are also present in the female reproductive system, central nervous system and gut. "The tricky thing about this disease is that many of the clinical symptoms are very similar to other more common conditions, such as ...
Scripps research team discovers a chemical pathway that causes mice to overeat and gain weight
...rs for prostaglandin E2 (PGE2), the most important inflammatory
mediator that controls a variety of physiological ...a directly couple the lack of a particular type of inflammatory
signaling via EP3R with leptin and insulin increase, glucose tolerance, and white fat accumulation, ...
New analyses reinforce efficacy of Remicade in treatment of severe psoriasis
... achieved a 75 percent improvement in the chronic, inflammatory
skin disease as measured by the Psoriasis Area Severity Index (PASI 75). In addition, in a separate analysis, investigators presented findings from a Phase 3 study, which showed that patients treated with REMICADE experienced significant and progres...
Remicade therapy shown to improve productivity in patients treated for chronic plaque psoriasis
...er further insight into the impact of this chronic inflammatory
disease on patient productivity and the effect of intervening with an appropriate biologic treatment, like REMICADE. We look forward to further studies to identify the economic implications of such productivity analyses in a real-world setting." I...
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