Tag: "inhibit" at biology news

Anti-seizure drugs slow aging in worms

...ms as model organisms to investigate how the drugs inhibit seizures in epileptic patients, a mechanism that currently is not well understood. Such research could lead to more effective treatments for epilepsy....

Study finds more than one-third of human genome regulated by RNA

...ructing a molecule called messenger RNA. MicroRNAs inhibit protein production by associating themselves with particular messenger RNAs, thereby reducing the amount of protein that's ultimately produced. In this study, the researchers determined which portion of the microRNA is most important for this process...

Celebrex prevents adhesions after surgery

...own for their use in arthritis. However, they also inhibit angiogenesis, or formation of blood vessels, and Celebrex also inhibits fibroblast activity, important in scar formation. These three properties make Celebrex a particularly good candidate for testing, Puder says, since adhesions are made up of infl...

JCI table of contents

...ws that drugs that interfere with erbB-1 signaling inhibit SPGF-induced viral replication and spread. The authors show that treatment with these erbB-1 inhibitors are effective in lowering morbidity and mortality, and boosting T cell immunity, in infected mice. In an accompanying commentary, Anthony Fauci ...

Stopping smallpox in its tracks: A new anti-viral approach

...ws that drugs that interfere with erbB-1 signaling inhibit SPGF-induced viral replication and spread. The authors show that treatment with these erbB-1 inhibitors are effective in lowering morbidity and mortality, and boosting T cell immunity, in infected mice. In an accompanying commentary, Anthony Fauci ...

Key trigger of opioid withdrawal symptoms found

...ke morphine and heroin. They believe that drugs to inhibit the chemical--called a transporter--could relieve ...Importantly, the researchers found that drugs that inhibit either the GABA transporter activity or protein kinase A eliminate the hyperexcitability of the PAG ...

Ingestion of afterbirth appears to promote maternal behavior in mammals

...ght on the way in which POEF modulates how opioids inhibit nociceptive processing in the nervous system -- processing in specific areas of the brain that recognize certain kinds of pain. Kristal says this research may lead to novel ways of treating addiction in humans by manipulating the effectiveness...

Green tea extract shows promise as an anti-cancer agent, UCLA study finds

...ct," Rao said. "If we knew exactly how it works to inhibit the development of cancer, we could figure out more precisely which bladder cancer patients might benefit from taking it." Numerous epidemiologic and animal studies have suggested that green tea extract provides strong anti-cancer effects in several ...

Mechanical tension helps shape lung development

... them to various chemical agents that stimulate or inhibit Rho's activity. In normal mice, photographs taken every 12 hours as the lungs grew showed each bud enlarging until a cleft formed in its tip, pinching it into two or three new buds. When lungs were treated with inhibitors of the Rho pathway, lung bu...

Scientists rid stem cell culture of key animal cells

...an embryonic stem cells to differentiate appear to inhibit differentiation in mouse embryonic stem cells. Aside from feeder cells, two other sources of animal material remain in stem cell culture materials. One, Matrigel, is a product that is essentially a plate-coating matrix of cells extracted from mouse t...

Familiar blood pressure drug may prevent osteoporosis

...cially since these mice are not obese." Drugs that inhibit the sympathetic nervous system are already commonly in use. They are called beta blockers and a study in the Journal of the American Medical Association (JAMA. 2004 Sep 15;292(11):1326-32) buttresses Karsenty's hypothesis, by demonstrating that older...

Signaling protein builds bigger, better bones in mice

...secreted signaling protein called Wnt10b. Known to inhibit the development of adipose tissue in mice, Wnt10b also stimulates the growth of bone cells, according to a new study that will be published February 21 in the Online Early Edition of the Proceedings of the National Academy of Sciences . "High levels...

Perchlorate found in dairy and breast milk samples from across the country

...ith low levels of iodide in breast milk, which can inhibit thyroid function in nursing womenan essential component for proper neural development of the fetus. Although the data are limited, the levels of iodide in this study are sufficiently low to be of concern, according to the researchers. They suggest th...

Elusive HIV shape change revealed; Key clue to how virus infects cells

...w route to inhibiting HIV by using compounds that inhibit the shape change," says Harrison. He notes that some HIV inhibitors already in development seem to inhibit the shape change; the new findings may help pin down how these compounds work and hasten their devel...

VCU researchers identify networks of genes responding to alcohol in the brain

...mption. If researchers can identify drugs that may inhibit or activate the function of one of the genes identified in these studies, they may be able to generate new treatments for alcoholism or addiction, Miles said. "The genes identified in our studies may eventually lead to other studies that can evaluate...

Research may provide ways to inhibit cancer's ability to resist treatments

... up the possibility that we can develop drugs that inhibit cancer's ability to repair itself and resist treatments," says Biochemistry professor Mark Glover, the lead author in the paper published in today's issue of Molecular Cell. Normally, explains Department of Oncology and Alberta Cancer Board researche...

JCI table of contents April 1, 2005

...here is a necessity to find new therapies that can inhibit these immune-based triggers and block liver damage. In a study appearing online on March 3 in advance of publication in the April 1 print edition of the Journal of Clinical Investigation, Christian Trautwein, Christian Klein, and colleagues from Hann...

New ways to ease liver disease

...here is a necessity to find new therapies that can inhibit these immune-based triggers and block liver damage. In a study appearing online on March 3 in advance of publication in the April 1 print edition of the Journal of Clinical Investigation, Christian Trautwein, Christian Klein, and colleagues from Hann...

Compound inhibits one critical pathway in breast cancer growth

...ity. "This compound showed a remarkable ability to inhibit Stat3 activity, more than any of the other 99 compounds that we tested," Lin said. The researchers then used STA-21 to treat several types of cells, including human breast cancer cell lines with constantly activated Stat3 as well as those without, an...

MUHC researchers make cancer target breakthrough

...late reductase, or MTHFR. Researchers were able to inhibit the function of the gene by creating antisense--an exact opposite of a tiny section of the MTHFR gene. "MTHFR is involved in the synthesis of methionine--a critical nutrient necessary for growth of cancer cells," explains Dr. Rima Rozen, principal in...

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(Date:7/31/2014)... bigeye tuna movements in the northwestern Atlantic Ocean led ... Center at the University of Massachusetts Amherst, found among ... range with pronounced north-south movements from Georges Bank to ... off Cape Hatteras southwest of Bermuda for foraging. , ... study one of the most important commercial tuna species ...
(Date:7/31/2014)... Science Foundation (NSF), counters a widely-held scientific view ... instead that certain Arctic lakes store more greenhouse ... , The study, published this week in the ... which occur as permafrost thaws and creates surface ... what was previously frozen land into lakes. , ...
(Date:7/31/2014)... GAINESVILLE, Fla. --- By tracing nearly 3,000 genes ... moths, University of Florida scientists have created an ... to use large-scale, next-generation DNA sequencing. , ... more closely related to small moths than to ... how butterflies evolved. The study also found that ...
Breaking Biology News(10 mins):Study of bigeye tuna in Northwest Atlantic uses new tracking methods 2Study of bigeye tuna in Northwest Atlantic uses new tracking methods 3Certain Arctic lakes store more greenhouse gases than they release 2UF study advances 'DNA revolution,' tells butterflies' evolutionary history 2UF study advances 'DNA revolution,' tells butterflies' evolutionary history 3
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