Research shows skeleton to be endocrine organ
...previously not recognized. Usually, an increase in insulin secretion is accompanied by a decrease in insulin sensitivity. Osteocalcin, however, increases both the secretion and sensitivity of insulin, in addit...Grapes, soy and kudzu blunt some menopausal side effects
...nd they can blunt cognitive loss, hypertension and insulin resistance in an experimental model. These an...Kudzu has also been shown to reduce blood glucose, insulin and leptin in this animal model of insulin resistance (a precursor to type 2 diabetes). Glucose tole...Identifying the mechanism behind a genetic susceptibility to type 2 diabetes
...xpression of TCF7L2 in human islet cells decreased insulin secretion in response to exposure to glucose. This study identifies TCF7L2 type 2 diabetes susceptibility variants and provides a mechanism by which these genetic variants might cause susceptibility to the disease. As discussed by the authors and in ...JCI table of contents: August 1, 2007
...xpression of TCF7L2 in human islet cells decreased insulin secretion in response to exposure to glucose. This study identifies TCF7L2 type 2 diabetes susceptibility variants and provides a mechanism by which these genetic variants might cause susceptibility to the disease. As discussed by the authors and in ...Insulin grown in plants relieves diabetes in mice; UCF study holds promise for humans
Capsules of insulin produced in genetically modified lettuce could hol... the key to restoring the bodys ability to produce insulin and help millions of Americans who suffer from insulin-dependent diabetes, according to University o...GI Caramba! Blue tortillas may help dieters and diabetics
...This reduces fluctuations in our blood glucose and insulin levels, helping to maintain a steady supply of energy. Low GI foods are said to have long-term health benefits, reducing your risk of heart disease and diabetes as well as aiding and maintaining weight loss. Juscelino Tovar, an author of the study...New clue into how diet and exercise enhance longevity
...throughout the body. The pathway is activated when insulin and insulin-like growth factor-1 switch on proteins inside the cell called insulin receptor substrates (Irs). Other researchers had shown that reducing the activity of the pathway in...New role for protein in fat cells may improve understanding of obesity and diabetes
... of important fats in fat cells, which can lead to insulin resistance a major contributor to diabetes and the abnormal release of cytokines, proteins that stimulate the immune system, Morton says. This unexpected contribution of CETP provides a new understanding of how our body stores and regulates fats an...JCI table of contents: July 19, 2007
.../article.php?id=30756 METABOLIC DISEASE In insulin resistance, all fingers point to diminished levels...nd type 2 diabetes are frequently characterized by insulin resistance a condition in which normal amounts of insulin are not adequate to produce a normal insu...Exercise, exercise, rest, repeat -- how a break can help your workout
...ine response while also having a rapid decrease in insulin concentration as a result of lower plasma glucose. This combination of high epinephrine and low insulin concentration may have also increased the lipolysis. There was also enhanced fat oxidation in the r...Metabolic syndrome -- don't blame the belly fat
... Yale University School of Medicine has found that insulin resistance in skeletal muscle leads to alterations...al Academy of Sciences (PNAS), demonstrates that insulin resistance in skeletal muscle -- caused by decreased ability of muscle to make glycogen, the stored ...Gene discovered for type 1 diabetes in children
... pancreas and makes patients dependent on frequent insulin injections to keep the bodys blood sugar under control. As the project continues, the study team expects to identify additional genes (perhaps as many as 15 or 20) thought to interact with each other in the disease. The study appeared July 15 in an...Researchers discover human embryonic stem cells are the ultimate perpetual fuel cell
... tissue such as neurons for Parkinsons disease, or insulin producing cells for diabetes . The research has been funded by the Canadian Institutes for Health Research and the National Cancer Institute of Canada. The Nature article is the latest in a series of important papers published by scientists at th...Boosting key milk nutrients may help lower type 2 diabetes risk
...s decreased by 15 percent. Type 2 diabetes and insulin resistance syndrome (or pre-diabetes) affect a staggering 75 million Americans and death rates from diabetes have increased nearly 45 percent over the past 20 years, elevating the importance of finding new ways to treat and prevent this deadly diseas...Insulin sensitizer also serves as energy-conserving signal to the brain
... obesity and type 2 diabetes may contribute to the insulin resistance that characterizes both conditions. In addition to its peripheral actions on the liver and skeletal muscle, adiponectin has also been reported to have central actions, Kadowaki said. Recently, however, it was reported that adiponectin is...New blood test might offer early warning of deep belly fat
...particular health concern as it has been linked to insulin resistance, type 2 diabetes, and heart disease ris...p showed that elevating RBP4 levels in mice causes insulin resistance and lowering them in obese mice can improve insulin sensitivity, the only known function ...Fat horses face health problems
...y because of its association with problems such as insulin resistance and laminitis. In fact, it was a spik...ypothesized that overweight horses may suffer from insulin and sugar imbalances, chronic inflammation, and oxidative stress, a malady that occurs as a result o...Pumpkin: A fairytale end to insulin injections?
...y replace or at least drastically reduce the daily insulin injections that so many diabetics currently have t...oosting levels of insulin-producing beta cells and insulin in the blood, reports Lisa Richards in Chemistry & Industry, the magazine of the SCI. A group, l...News tips from the Journal of Neuroscience
...travenous 2-deoxyglucose, a glycolysis blocker, or insulin rapidly increased phosphorylated levels of p44/42 mitogen-activated protein kinases (phospho-ERK1/2) in the PVH. Microinjection of NE into the PVH had a similar effect. Downstream effects included a rise in PVN c- fos messenger RNA and plasma levels......te the pancreatic islets have been shown to target insulin B chain amino acids 923 (insulin B:923), and NOD mice lacking insulin B:923 are protected from diabetes. This suggests that insulin, specifically the insulin B:923 sequen...