Tag: "insulin" at biology news
Cord blood may preserve insulin levels in children with type 1 diabetes
..., Fla. -- Umbilical cord blood may safely preserve insulin
production in children newly diagnosed with type 1...aluated for the next two years to measure how much insulin
they were making on their own and to assess blood sugar levels and the function of key immune system...
Modified mushrooms may yield human drugs
...nce. The test demonstrates that if a second gene, insulin
for example, were to be patched in the plasmid, that gene would be expressed as well. "There is a high probability that if the mushroom cell has the hygromycin resistance gene, it will also have the partner gene," Dr. Romaine added. The degree of ...
Weizmann Institute scientists develop a general 'control switch' for protein activity
...he way for the development of a treatment based on insulin
injections. Yet, despite enormous research efforts led by scientists worldwide, the cellular function of numerous proteins is still unknown. To reveal this function, scientists perform various genetic manipulations to increase or, conversely, decreas...
Inflammation is at the origin and progression of diseases such as diabetes or cancer
...ed in inflammatory processes that end up promoting insulin
resistance. There are currently several drugs in clinical testing that inhibit cytokines as a treatment for diabetes. Not all anti-inflammatory drugs work for all diseases. The challenge is to identify and understand complete mechanisms so that the m...
Cytokine resistance contributes to pathology of type 2 diabetes
...tudied and well understood. The second, called the insulin
receptor substrate 2 / phosphatidylinositol-3 kina...the actions of diabetes is to create intracellular insulin
resistance, Freund said. Some of the cytokines that work on cells share the same pathways as the ins...
JCI table of contents: June 14, 2007
...ETABOLIC DISEASE Uncoupling a high-fat diet from insulin
resistance and diabetes Insulin resistance is ...t against the development of high-fat diet-induced insulin
resistance. Uncoupling proteins act to convert stored fat into thermal energy. In the current stud...
5.9 million award gives UK aging research a new lease on life
...tode worms and mice, and in particular the role of insulin
signalling. Recent research has revealed that changes to single genes can make animals live longer, by maintaining health and delaying the onset of ageing-related diseases, such as cancer, diabetes and cardiovascular disease. "What is particularly ...
Slow wave activity during sleep is lower in African-Americans than Caucasians
...ir reported poor sleep quality and higher risk for insulin
resistance." The amount of sleep a person gets affects his or her physical health, emotional well-being, mental abilities, productivity and performance. Recent studies associate lack of sleep with serious health problems such as an increased risk ...
Hormone that signals fullness also curbs fast food consumption and tendency to binge eat
...en eating and is known to work in partnership with insulin
to regulate blood sugar. Pramlintide is also under development as a potential drug for obesity. The study was carried out in 10 U.S. research sites and was reported by Steven R. Smith of the Pennington Biomedical Research Center in Baton Rouge, La...
Scientists honored with 'Excellence in Clinical Research Award'
...es that proved to be effective at regenerating the insulin
producing beta cells that are lost when people develop type 1 diabetes. These researchers are investigating ways to stimulate the existing beta cells left in diabetes patients to regenerate by applying combination therapies. If combined with therap...
Story ideas from the Journal of Lipid Research
...ood sugar is higher than it should be and too much insulin
is produced to counter this blood sugar increase. Patients with this disease have increased levels of triglycerides the most important type of fat in their blood and high levels of a chemical called triglyceride-rich lipoprotein (TRL) that carries ...
Adult stem cells from human cord umbilical cord blood successfully engineered to make insulin
...ery tells us that we have the potential to produce insulin
from adult stem cells to help people with diabetes... stem cells produced both C-peptide, a part of the insulin
precursor protein, and insulin
itself. Confirming the presence of the C-peptide was especially cruci...
JCI table of contents: May 24, 2007
...amma in macrophages resulted in the development of insulin
resistance in the livers of lean mice fed a normal diet, as well as impaired insulin
signaling in fatty tissue, liver, and muscle. The authors went on to show that insulin
Latest strategies for moving research toward a cure for diabetes explored at global scientific forum
... goal to help restore the bodys ability to produce insulin
on its own, reducing the need for insulin
injections and lowering the risk for diabetes-related complications including heart disease, kidney ...
New techniques redefine assessment of liver disease
...at) in the abdomen and medical disorders including insulin
resistance (IR, inadequate response to insulin) an... Nearly all of these proteins are associated with insulin
signaling, which leads to abnormal blood glucose levels and diabetes, leading researchers to the con...
IMS updated recommendations on postmenopausal hormone therapy
...reduces the risk of diabetes and, through improved insulin
resistance, it has positive effects on other related risk factors for cardiovascular disease such as the lipid profile and metabolic syndrome. In women less than 60 years old, recently menopausal and without prevalent cardiovascular disease, the in...
Insulin therapy shown to treat early experimental diabetic retinopathy
...lts that indicate that subconjunctivally delivered insulin
ameliorates degenerative and inflammatory response.../Broward County Convention Center. Regular human insulin
in doses ranging from 0.01U to 1U was injected subconjunctivally in control and 1 month diabetic mal...
Study shows marine omega-3 fatty acids have positive effect on muscle mass
...e exact cause of this phenomenon is still unclear, insulin
resistance of aging muscle cells has been suggeste...e glucose metabolism in people and animals showing insulin
resistance, the researchers decided to test whether omega-3s could also influence protein metabolism...
Fat screen delivers plant-derived chemical with antidiabetic effects
...s. The work suggests a new approach for treating insulin
resistance that might complement the use of preexi...through a counterintuitive mechanism: they restore insulin
sensitivity by activating a central promoter of fat tissue production called peroxisome proliferator...
The stem cells that weren't there
...tely, if diabetes researchers learn how to control insulin
production, we can better treat patients who now c... treatment. Rather, it advances basic knowledge of insulin
biology that could form a foundation for eventual therapies. Currently, patients with type 1 diabe...
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