Keeping the immune system from starting a 'food fight'
...lso showed symptoms of metabolic syndromeincluding insulin resistance and fatty liver diseaseeven while eatin...array of associated metabolic disorders, including insulin resistance, fatty liver disease, type 2 diabetes, and cardiovascular disease. This cluster of chroni...Salk researchers discover first gene that specifically links calorie restriction to longevity
...tion of glucagon, a pancreatic hormone that unlike insulin increases the concentration of blood sugar and maintains the bodys energy balance, especially during fasting. The potential payoff for cutting to 60 percent of normal while maintaining a healthy diet rich in vitamins, minerals, and other nutrients,...Study shows tight diabetes control does not impact cognitive ability in type 1 diabetes
...he group received intensive therapy with either an insulin pump or three or more daily insulin injections. The remaining subjects received conventional therapy of one to two insulin injections da...A cherry on top: Tart cherries may alter heart/diabetes factors
...t had total cholesterol, triglyceride, glucose and insulin levels that were significantly lower than those of...of increased cholesterol and decreased response to insulin that can lead to cardiovascular disease and Type 2 diabetes. Meanwhile, the measure of PPAR messen...TXNIP -- regulator of glucose homeostasis and potential diabetes drug target and more
...gene whose expression is reciprocally regulated by insulin and glucose, TXNIP levels are consistently higher than normal in patients with type 2 diabetes and prediabetes, and such elevated levels can inhibit glucose uptake in muscle and fat cells. Mootha and colleagues propose that TXNIP normally regulates a...Cherries may help reduce metabolic syndrome and heart disease risk factors
...ch as cherries." Metabolic syndrome (also called insulin resistance syndrome) has become increasingly commo...y lowered total cholesterol levels, triglycerides, insulin and fasting glucose levels after 90 days. All of these measures are factors that are linked to meta...'Exercise pill' switches on gene that tells cells to burn fat
...fat in the blood, heart disease, and resistance to insulin and diabetes. Dr. Evan's Experimental Biology presentation on April 30 is part of the scientific program of the American Society for Biochemistry and Molecular Biology. This chemical switch is not the first success Dr. Evan's laboratory has had...Oxford physiology professor earns APS' Walter B. Cannon Award
...these children have been able to switch from daily insulin injections to a daily pill, transforming both thei... disease occurs when the body does not make enough insulin for its needs. Dr. Ashcroft's research has provided insights into how insulin is normally secreted b...Researchers identify new genetic risk factors for type 2 diabetes
... by the resistance of target tissues to respond to insulin and a gradual failure of insulin-secreting cells i...h factor 2 is thought to play a role in regulating insulin action. CDKAL1. This gene codes for a protein called CDK5 regulatory subunit associated protein1...Landmark study highlights complex genetic risk factors behind type 2 diabetes
... result of a failure of the body to produce enough insulin to maintain normal levels of glucose (sugar) in th...y compounded by a reduction in the capacity of the insulin released to work properly in tissues such as muscle and fat (known as insulin resistance). It is a m...U of M-led study identifies new genetic risk factors for type 2 diabetes
...d sugar, caused by the body's inability to utilize insulin to move blood sugar into the cells for energy. Typ...h factor 2 is thought to play a role in regulating insulin action. CDKAL1. This gene codes for a protein called CDK5 regulatory subunit associated protein1-l...Genome-wide search unearths surprising clues for diabetes and triglycerides
...nd other cardiovascular risk factors such as blood insulin levels, cholesterol levels, blood pressure and body weight. Each of these traits is considered "complex" because it involves a mix of inherited, environmental and behavioral factors. The scientists approach, known as a "genome-wide association stu...Humans aren't the only ones with obesity problems
...weight gain but also endocrine problems, including insulin resistance. The equine obesity risks have been les...forced to euthanize the horse. Horses that develop insulin resistance are at an increased risk for laminitis, Johnson said. Although society views hu...Study shows food preparation may play a bigger role in chronic disease than was previously thought
...and pasteurized, have been linked to inflammation, insulin resistance, diabetes, vascular and kidney disease, and Alzheimers disease. A new study at Mount Sinai School of Medicine reveals that AGE levels are elevated in the blood of healthy people, and even more so in older individuals than in younger peo...Bioluminescence at the service of a novel cerebral imaging technique
...en shown that flies endowed with a mutation of the insulin receptor live much longer. It is also possible to exploit the powerful genetic tools of the Drosphila to study and compare these maps in flies bearing different mutations, or in flies which serve as models for a variety of human pathologies, such as...ACS News Service Weekly PressPac -- April 11, 2007
... effects in rodents, including obesity, cancer and insulin resistance. There is growing concern that the chemical may cause similar adverse effects in humans, particularly in babies and young children. But there are vast discrepancies in the findings of government-funded and industry experiments that have ex...Study examines calorie restriction and glycemic load
...nant of weight loss for people with high levels of insulin secretion, such as people with diabetes. "We have observed that for some groups, glycemic load may impact weight loss. However, in terms of calorie-restricted diets, we see little difference among diets of varying glycemic load when we account for fa...India's biotech industry emerging as world innovator, collaborator, competitor
...n remains Indias most affordable human recombinant insulin product. If the above trend continues, the cost ... firms are scaling up to manufacture such drugs as insulin and interferon, their facilities refurbished or built in accordance with the standards of internatio...Glucose triggers brain cell death in rats after hypoglycemic coma
...ergy. Diabetics do not produce enough of their own insulin and must take it several times a day. A severe insulin overdose can reduce levels of glucose in the blood to extremely low levels a condition known as hyp...Mutation in HNF4A associated with an increase in birthweight and macrosomia
...e a key role in the regulation of the secretion of insulin by the pancreas. In addition to increased birth... researchers were able to show that there was high insulin during development and low blood sugar at birth. Although this study is in patients with an unusu...