Imbalance may trigger advance from fatty liver to liver failure
...for this epidemic of liver disease associated with insulin resistance and metabolic syndrome, the researchers said. The growing trend has the potential to lead to a worrying increase down the line of people in need of liver transplants, said study author Andrew Mason of the University of Alberta's departmen...Ghrelin: A player in diabetes but not obesity?
...ke a major role in maintaining the balance between insulin and glucose and the development of diabetes, said ...re resistant to glucose because they secreted more insulin in response to the glucose challenge," said Smith. When Sun and Smith investigated further, they f...Scientists find gene in obese mice that increases type 2 diabetes
... caused by obesity. Obese individuals tend to have insulin resistance; that is, it takes more insulin for the body to respond normally. Type 2 diabetes occurs when the pancreas is unable to manufacture ...Joslin Diabetes Center partners with St. John Health's Providence hospital in Michigan
... management, continuous glucose monitoring system, insulin pump therapy, gestational diabetes education series and access to specialist referral and follow-up care....Insulin research builds on Nobel Laureate's work
...molecular processes whereby pancreas cells release insulin into the bloodstream. The breakthrough, which buil...atment of diabetes which is caused when not enough insulin is released by the pancreas to meet the body's demands. The team of scientists from the University o...New technology enables faster, more efficient cell harvest: Cell therapy meeting study
...injury and regenerate pancreatic tissue to produce insulin for people with diabetes. Regenerative medicine promises to improve health and quality of life by supporting and activating the body's natural healing abilities....Researcher predicts paradigm shift in heart disease treatment
... to play important roles in the pathophysiology of insulin resistance and diabetes. The term cardiometabolic risk describes the interaction of each of these elements as they relate to the development of cardiovascular disease. "It seems as though the EC system receptors are overactivated when 'fattening food...APS research awards go to undergrads at Colorado State, Michigan State, Oberlin, Williams
...dulin increases heart rate in mice, independent of insulin and catecholamines," by Gillian Louise Sowden, and Steven John Swoap, Williams College, and David Weinshenker of Emory University, Atlanta, GA. Sowden expects to graduate this year and plans to attend medical school and eventually combine research an...Gene variant protects against type 2 diabetes, heart disease, and hypertriglyceridemia
...constellation of conditions that includes obesity, insulin resistance, and hypertension. The identification of the T-87C variant indicates that aP2 might play a similar role in humans as it does in mice. The significance of this finding may include a potential target for drugs designed to reduce aP2 levels,...Joslin's C. Ronald Kahn, MD, to discuss genetics of obesity at AACE meeting
...Kahn's research has literally defined the field of insulin signal transduction and mechanisms of altered sign...In 1981, Dr. Kahn's laboratory discovered that the insulin receptor is an insulin-stimulated enzyme with protein tyrosine kinase activity. His laboratory also ...Joslin-led study reveals findings on how insulin-producing beta cells grow and function
...ate beta cell growth and understand the defects in insulin production and secretion that cause diabetes. The...w.nature.com/ng . In two previous Joslin studies, insulin receptor, a protein that mediates the action of insulin, and the receptor for insulin-like growth fa...LIAI scientists make major finding on potential cure for type 1 diabetes
...ls. As a result, type 1 diabetes sufferers inject insulin daily to control blood sugar levels. However, complete control is difficult to achieve and damage to body organ systems can still occur. Complications from type 1 diabetes can include kidney failure, adult blindness and the need for amputations. "...Diabetes and cancer: Alpha connection
...tudy showed that p110 alpha controls the action of insulin and other key hormonal signals that play roles in ...els of body fat. Additionally, the mice had raised insulin levels and were glucose-intolerant. However, the mice did not go on to develop full diabetes. "The f...Cancerous vs. healthy cells: Researchers identify the road to success
...nhibitors is to avoid blocking the closely related insulin receptor that regulates glucose levels in the blood. Results from the study showed that in addition to diminishing or halting tumor growth in human cancer cells transferred to live test animals, OSI's IGF-1R inhibitor showed no substantial rise in b...Losartan prevents life-threatening insulin resistance in burn injuries
... FRANCISCO Researchers have found a way to prevent insulin resistance in burn-injured rats, a finding that, w...-angiotensin system (RAS) as the key to preventing insulin resistance -- a unique line of inquiry in burn research, according to lead author Sherry O. Kasper. ...Salk scientist Ron Evans wins 2006 Gairdner Award for his discovery of hormone sensors
...cterized by high blood pressure, heart disease and insulin resistance. About Dr. Evans: Born and raised in Los Angeles, Dr. Evans earned his bachelor's degree in bacteriology and his doctorate in microbiology and immunology from the University of California, Los Angeles. After completing a postdoctoral res...Liver signal critical for insulin's brain action
...s a key player in the body's ability to respond to insulin action in the brain by ratcheting down the export ...levels and can export glucose as well as store it, insulin not only promotes the storage of glucose but also inhibits the production of sugar for export," expl...Pine nut oil boosts appetite suppressors up to 60 percent for 4 hours
... monitored, and CLA was found to have no effect on insulin resistance. *Paper presentations: "Conjugated lino...ith conjugated linoleic acid (CLA) does not induce insulin resistance in overweight and obese" 12:30- p.m. 3 p.m. Wednesday, April 5, Human and Clinical Nutri...Einstein researchers identify genetic variants that lend clues to living longer
...ealth, lower incidence of hypertension and healthy insulin metabolism. "Since centenarians typically escape cardiovascular disease, diabetes, and other age-related disorders, we suspected these most senior of senior citizens might possess gene variations that help them reach a ripe old age," said Dr. Nir Bar...Researchers reverse juvenile diabetes in animal model; Clinical trial FDA approved
...nabled the pancreas of the mice to begin producing insulin again," said Dr. Trucco, who also is the Hillman P...in. Dr. Trucco believes that adding small doses of insulin to the dendritic cells will help guide the dendritic cells directly to the T cells. Adding the insul...