'Preconditioning' helps protect brain's blood vessels from stroke
...trengthen brain cells against damage from a larger insult later on. This phenomenon occurs naturally in the human brain," explains lead researcher Dr. Alexander Kunz of the University of Dresden, Germany. Dr. Kunz worked on the study while at Weill Cornell. But exactly how does preconditioning work, and c...Tracing Parkinson's lethal mechanism
...use of a genetic defect, but because some external insult triggers the death of dopamine-producing neurons. Now, researchers have reported progress in understanding the mechanism underlying that death, which they say suggests a new treatment pathway. In both mice and human patients, the researchers have f...Hearts of male and female rainbow trout are different
...production during reoxygenation -- after a hypoxic insult -- significantly improved in males receiving DCA, but not females; male ventricle tissue had 2.5-fold higher citrate concentrations than females; and; males had a proportionately larger epicardium to endocardium ratio compared with females ...New neurons could act to alleviate epilepsy
...nstrates that both a physiological stimulus and an insult to the adult brain trigger the formation of new dentate granule cells, which are functionally integrated into hippocampal neural circuitry," concluded Lindvall and colleagues. They wrote that "following insult, the functional connectivity of new neur...Story tips from the Department of Energy's Oak Ridge National Laboratory, November 2006
...ts and mechanisms that can simulate just about any insult the world can throw at a piece of equipment. Team leader Peter Chiaro said the project looks at and mimics real-world situations such as extreme temperatures, humidity, air pressure, magnetic fields, electromagnetic interference, ionizing radiation, ...Gene therapy inhibits epilepsy in animals
...nhibited the development of epilepsy after a brain insult in animals. By using gene therapy to modify signal... that there is a window to intervene after a brain insult to reduce the risk that epilepsy will develop," said one of the lead researchers, Amy R. Brooks-Kaya...Naked mole-rat unfazed by oxidative stress
...e-rat is able to fend off the occasional oxidative insult that can occur, and that may be more important than what happens with the steady-state levels of oxidative stress that result from normal metabolic activity. Buffenstein theorizes that the naked mole-rats in her laboratory suffer higher levels of o...Distinguishing friend from foe in the battle against cancer
... treated with rapamycin actually survived cellular insult better than untreated cells-a highly inauspicious outcome if the goal is to kill cancer cells. The Hunter and Verma team found that rapamycin did that by increasing NF-kB activity in the TSC null cells when they were exposed to chemotherapeutic drugs...... that the innate immune response against an immune insult produces measurable phenotypic and functional damage to self-tissue in the beetle Tenebrio molitor. This type of self-harm (autoreactivity) and the life-history implications that arise from it, are central to understanding evolutionary phenomena such...'Uniquely human' component of language found in gregarious birds
...he starling. It should no longer be considered an insult to be called a bird brain." Although they are not known for the lilting beauty of their songs, starlings produce an amazing array of complex sounds, combining chirps, warbles, trills and whistles with rattling sounds. They also have a talent for mi...Chlamydia parasite lives off our fat
...ogens are essentially lipid parasites. So, to add insult to injury, Chlamydia apparently lives on our fat. Lipid droplets are fat-rich structures found in all eukaryotic cells. In humans, lipid droplets are abundant in adipocytes, our professional fat storage cells, where they have traditionally been regar...Sea urchins' unexpectedly diverse 'innate' immune capability points to new research avenue
...rple sea urchin's response to a standard bacterial insult (a fragment of the cell wall called lipopolysaccharide, or LPS) using a genomic screen. They discovered that the sea urchin produces a surprisingly large number of proteins against LPS, and that many of them are similar but also show an unexpected am...Inherent vascular repair key to atherosclerosis
...sually begins with an immune system response to an insult or injury to the arterial lining, said Goldschmidt. Once there, these cells recruit lipids and other fatty materials to the damage site, essentially creating a scar. Over time, the affected arterial cells themselves change, creating a narrower and le...Duke researchers uncover genetic link to stroke after heart surgery
...enes are involved in the body's immune response to insult or injury, the researchers said that their findings strongly suggest that inflammation plays an important role in post-operative stroke. The researchers said that if the findings are confirmed by more extensive studies, they could become part of a ba...Cigarette smoke exacerbates alcohol's effects on defense against Streptococcus pneumoniae
...ntifies a potential adverse effect of the combined insult of alcohol consumption and smoke exposure on bacterial burden in the lower respiratory tract, the small sample size precluded definitive conclusions from being made on this adverse effect. Future studies are needed to both describe the effects of al......s indicate the degree of response to environmental insult at cellular and molecular levels - early warning signals of the effects of pollution in the ocean. Amongst other parameters, the mussels are analysed to determine whether they have accumulated metals or hydrocarbons, whether they are stressed, have ...Prominent North Shore-LIJ physician-researcher brings science to the masses with new book
...gins when the body's natural immune response to an insult or infection gets so out of control that it starts to impair the functioning of major organs, often leading to multiple organ failure and death. The syndrome is serious, taking the lives of about a third of those afflicted with it. A normal immune re...Duke researchers uncover genetic link to kidney damage after heart surgery
...the kidney, may contribute not only to the initial insult during low blood flow, but also throughout the recovery phase." Some other polymorphisms also examined by the researchers showed smaller abilities to predict renal dysfunction after surgery. While these associations were weaker, Stafford-Smith said t......ssion, making brain synapses more resistant to the insult caused by the accumulation of Abeta. The beneficial effect of rolipram treatment was found to extend for at least 2 months after the end of one course of the treatment. The authors also found that the beneficial effects of treatment were not limited ...