NIH awards nearly $21 million to fund cutting-edge research equipment
...re dissociation, and top down mass measurements of intact proteinswill be housed in the cancer center and mass spectrometry/proteomics facility to ensure optimal performance and research productivity. University of Connecticut School of Medicine and Dentistry (Farmington, Conn.)$2,000,000.An 800 megahert...Dartmouth professor makes case for ethically universal stem cell lines
...of deriving hESCs that either leave the blastocyst intact and unharmed or avoid the use of normal blastocysts in the first place. The paper explains the science behind the six approaches and describes the hurdles that must be overcome in making them useful in future stem cell research. Even though none o...Satellite images show destroyed and threatened villages in Darfur
.... The new site includes up-to-date images on 12 intact but vulnerable villages as well as archival satell...village called Donkey Dereis, in south Darfur, was intact when photographed at the end of 2004. An image two years later shows the near total destruction of t...Simulations unravel outer membrane transport mechanism
...nd the luminal domain were strong enough to remain intact while TonB pulled the end of the luminal domain away from the barrel. The simulation also showed the luminal domain gradually unfolding, changing its conformation in ways that would open up enough space for a molecule of vitamin B12 to pass through t...Researchers find 24 species believed new to science in Suriname rainforest
...Suriname has some of the Amazons most pristine and intact rainforest, which offers huge potential for scientific research and economic investment in carbon sequestration, as well as the sustenance it has always provided local communities, said Leeanne Alonso, a Conservation International (CI) vice president...New research shows sharks use their noses and bodies to locate smells
...n two sensory conditions with their lateral lines intact or lesioned by streptomycin," explained Gardiner. ... on hair cells. Sharks with their lateral lines intact demonstrated a preference for the odor plume over the seawater plume and, more specifically, for the...Repair of DNA by Brca2 gene prevents medulloblastoma
...ated the gene from the nervous system, but left it intact in the rest of the body. The use of this technique was important because previous studies showed that mouse embryos cannot develop when the gene is absent from all the cells of the body. The team observed how the specific loss of Brca2 activity from...Brain, size and gender surprises in latest fossil tying humans, apes and monkeys
...about 29 million years ago. The second and most intact cranium found of Aegyptopithecus zeuxis was identified by Duke University primatologist Elwyn Simons, who is announcing the find this week with several colleagues. Because of the new specimen's remarkable wholeness, Simons and his colleagues were abl...Essential genes cluster clue to order in the genome
...he reason this part of the chromosome has remained intact is that it has densely packed essential genes. If the chromosome broke anywhere, the organism would not develop," she said. The finding also begs the question as to whether genes need to be transcribed (or have their message read to enable producti...National Academy of Sciences elects 2 Rutgers professors
... positions along or between chromosomes, remaining intact and functional in the process. With chromosomal exchanges limited to the sequences between gene-coding regions, Dooner found that genes remain unscathed in different neighborhoods. The result is functional genes in multiple neighborhoods, concluding ......lly in a dose-dependent manner. The force curve of intact DNA is characterized by a plateau region. This characteristic plateau is drastically reduced in width with increasing exposure to UV light. UV light induces the crosslinking of the constituent DNA bases within the polynucleotide chains, as well as ...Study shows hibernating bears conserve more muscle strength than humans on bed rest do
... resistance, and in vivo contractile properties of intact muscles in bears within their natural dens." Adapting a system used for the evaluation of neuromuscular disease progression in humans, the researchers tested black bears from Middle Park, Colorado, both early and late in the hibernation cycle. Afte...Different approach needed to protect brains of premature infants
...eps all the connections, structures and cell types intact and in their proper relationship. Our ability to observe these connections at the microscopic level provides a new window for understanding perinatal brain injury. To probe how the brain's response to injury changes, researchers took slices from th...A 'traffic light' for neurons means 'go' for improving brain research
...over specific neural cells in living creatures and intact circuits," says Deisseroth, whose Stanford research group collaborated with researchers at the Max Planck Institute of Biophysics, the Johann Wolfgang Goethe University in Frankfurt and the University of Wrzburg in Germany. "This gives us the power t...... advancing human settlement fragmenting previously intact forests where elephants live. The authors walked over 6000 kilometers (3,700 miles) in five countries, and covered more than 68,000 square kilometers (26,000 square miles) in systematic surveys. They found that elephant abundance plummeted near roa...Selective amnesia -- How a traumatic memory can be wiped out
...that the memory was wiped out by the drug, leaving intact the memory associated with the other sound. The researchers also recorded the neuronal activity of rats in the amygdale, an area of the brain associated with emotional memory. Neuronal activity increased when remembering the traumatic memory, bu...Moral judgment fails without feelings
...cit is, he said. Damage to the frontal lobe leaves intact a suite of moral problem solving abilities, but damages judgments in which an aversive action is put into direct conflict with a strong utilitarian outcome. It is the feeling of aversion that normally blocks humans from harming each other. Damasio ...UA researchers identify new adherence factor, Pili, produced by tuberculosis
... recent outbreaks. "AIDS patients, who do not have intact immune systems, are highly susceptible to TB infection. This is a major reason for the worldwide increase in the incidence of TB. This increase also is associated with poverty, the growing numbers of homeless, alcohol- and drug-abusing populations, a...Other highlights in the Feb. 21 JNCI
...ion of the melanoma cells. Only the cells with the intact form of KISS1 secreted kisspeptins, and these cell...ion. Mice that were injected with the gene for the intact KISS1 protein lived much longer, on average, than the mice with the non-secretable KISS1 cells. Furt...Survey finds perceived risk of recurrence low in African-American breast cancer survivors
... with either lumpectomy or mastectomy, and had one intact breast. All of the women were offered the opportunity to participate in genetic counseling. The researchers found that 53 percent of respondents felt they had the same or a lower risk of developing breast cancer again compared to other women, but t...