Analysis reveals extent of DNA repair army
...ion develops. But precisely how cells monitor the integrity of their genomes, identify problems, and intervene to repair broken or miscoded DNA has been one of nature's closely held secrets. Now, however, a report in the journal Science describes a new database developed by a team of researchers from the Howa...Virus widely used in gene therapy research yields important clues to genomic instability
...icant source of DNA breaks, which may threaten the integrity of the mammalian genome. More importantly, they can contribute significantly to our understanding of the possible contributions to cancer and aging," he explains. ...News tips from the Journal of Neuroscience
... Thus, the cytomatrix appears not to depend on the integrity of synapsins. 2. Early Glucocorticoids and Later Neuroprotection Paola Casolini, Maria Rosaria Domenici, Carlo Cinque, Giovanni Sebastiano Alem, Valentina Chiodi, Mariangela Galluzzo, Marco Musumeci, Jerome Mairesse, Anna Rita Zuena, atrizia Matt...Antibody linked to MS significantly higher in spinal fluid of blacks
...n the amount of IgG in the patient's blood and the integrity of the blood-brain barrier, which limits access to the brain. "High IgG levels in a healthy person's bloodstream can cause this antibody to seep over into the cerebrospinal fluid, so a high level of spinal IgG isn't by itself very revealing," explai...Tough tubes -- Carbon nanotubes endure heavy wear and tear
... stress yet retain their structural and mechanical integrity is similar to the behavior of soft tissue, according to a new study from Rensselaer Polytechnic Institute. When paired with the strong electrical conductivity of carbon nanotubes, this ability to endure wear and tear, or fatigue, suggests the mater...Unraveling the physics of DNA's double helix
...ical attraction between the stacked bases. But the integrity of double-stranded DNA depends on both the stacking forces between base units along the length of the double helix and on the pairing forces between complementary bases, which form the rungs of the twisted ladder. Earlier studies have focused more...Effects of aging in stem cells
...portant for regulating gene expression and genomic integrity became less active. These results lend strong support to the notion that HSCs succumb to the wear and tear of aging, just like other cells, and shed light on the mechanisms of aging. To study HSCs regenerative capacity over time, Chambers et al. i......to any number of shapes with no loss of mechanical integrity or efficiency. The paper batteries can also be stacked, like a ream of printer paper, to boost the total power output. Its essentially a regular piece of paper, but its made in a very intelligent way, said paper co-author Robert Linhardt, the Ann a...