UCSD medical researchers use brain cell transplants to correct muscle spasms after aneurysm surgery
...ansplantation of well defined human neuronal cells into a specific region of the spinal cord can be an effective treatment for spasticity in cases of ischemic spinal cord injury," said the study's lead author, Martin Marsala, M.D., UCSD associate professor of anesthesiology. "While we believe the transpla...UCLA scientists discover new way to fix defective gene
..., created a new strategy for tricking the ATM gene into overlooking certain types of mutations called premature termination codons (PTCs). "PTCs are like irregular stop signs located in the middle of the block," explained Gatti. "They stop traffic before it reaches the intersection. We made these stop s...Excess dietary fat accelerates breast cancer by altering the activity of a group of genes
... caused by dietary lipids. More extensive research into these genes is required to discover whether the me...igated. The discovery opens a new line of research into its implication in changes on the state of cellular differentiation induced by dietary lipids in bre...An old adage about apples finds scientific backing
... "These studies not only offer insights into the mechanisms of the chemopreventive properties o...h scientists split the polyphenols found in apples into two general categories: polyphenol monomers which include flavonoids (catechins and epicatechins); a...Rutgers is on the 'NIH Roadmap'
...with researchers in that area and ease their entry into other biological fields. The course also provides material for the BioMaPS Web site and the curriculum for a semester-length course taught by Olson and Ehrlich. The first short course focused on gene transcription and was held at Rutgers this past s...UT Southwestern researchers uncover process for sugar-induced fat formation
... genes that cause cells in the liver to turn sugar into fat. Their work appears in two studies in Proce...re enzymes are mobilized to rapidly convert sugars into fat; and a slower response, in which several different genes are turned on and off, creating more en...Small business at NJIT's business incubator takes two awards
... device which can be implanted through the urethra into the bladder via a simple procedure that does not require surgery. The device contains a metal valve which opens whenever the user wants and is activated by a pocket-sized magnetic wand the user carries. Urovalve's device will improve the quality of...Discovery might improve design, effectiveness of anti-cancer drugs
...ntaining the enzyme was introduced as a fine spray into a vacuum created in a mass spectrometer in the lab...s for many seconds through a nearly perfect vacuum into which the water molecule would evaporate instantly if it were exposed to the surroundings." Inside t...Peakadilly nv biopharmaceutical firm created
... Proteomics can also provide insight into the origin and progression of diseases. The analysis of the effect of a drug on the proteome enables researchers to understand which protein(s) the drug acts upon. Until recently, however, there was no efficient way to study the proteome systematical...Medical geneticists elected to Institute of Medicine
...translate the findings of the Human Genome Project into new strategies for improving human health. The IOM...tute and plays a lead role in integrating genomics into medical practice. In addition, as director of NHGRI's Office of Policy, Communications and Education...Common gout drug shown to reduce risk from colorectal cancer
...mputerized prescription records. The study took into consideration other known risk factors for colorectal cancer, including aspirin or other NSAID use, first-degree family history for colorectal cancer, ethnicity, sports activity and vegetable consumption. Allopurinol is thought to...Consuming fruits and vegetables lowers risk of developing NHL
...stigator of the study. "However, even after taking into account other possible risk factors like smoking, our results are consistent to those of studies where diet was assessed in healthy people who were followed forward in time to see if they develop cancer. A novel finding was the lower risk observed ......form between developing bones subsequently develop into the permanent cartilage found in joints. Several members of a family of secreted proteins known as bone morphogenetic proteins (BMPs) are expressed in these stripes of cells, implicating BMP signaling (the transmission of messages produced by BMPs bi...Two UT Southwestern physicians elected to National Academy of Sciences' Institute of Medicine
...f current UT Southwestern faculty members inducted into the institute to 17, the largest representation in Texas and surrounding states. Members of the Institute of Medicine shape policies affecting public health and advise the federal government on issues involving medical care, research and educatio...ASPB opposes proposed ban of GMOs in Humboldt county ballot measure M
...nalty and/or imprisonment shall be imposed, taking into account the amount of damage, any potential damage...es in 2001. Reduction in the release of pesticides into the environment, including our lakes, rivers and streams, cut down dramatically on exposure to harsh...Gene linked to greater risk of heart disease in type 2 diabetes
... CD36 is involved in transporting free fatty acids into cells. It also is a scavenger of oxidized "bad" cholesterol LDL at the arterial wall. All are major players in contributing to atherosclerosis -- the dangerous buildup of plaque that can lead to partial or complete blockage of the artery, leading to ...Other highlights in the October 20 JNCI
...athecal Methotrexate An injection of methotrexate into the spinal fluid is used in some cancers to preven...hotrexate administered intrathecally--by injection into the spinal fluid--can occur from medication preparation errors or when the drug is prescribed for sy...Lag-3 gene dampens immune responses by controlling regulatory T-cell function
...lls during an immune system response, turning them into regulatory cells that put the brakes on the activi...e CD4+ T cells are activated in cells that develop into regulatory T cells. The investigators found that the Lag-3 gene was "expressed" (being used by the c...Gene-altered mouse is model for rare autoimmune syndrome
...searchers, the achievement not only offers insight into Sjgren's syndrome, but into the general developmental machinery of the immune system. The immunologists, Yuan Zhuang, HongMei...Establishment of an International Council for Science Regional Office for Africa
...anning to ensure that African priorities are taken into account in setting the international agendas. Through collaboration with the international science community, the Office will assist in scientific capacity building in Africa. Further, it will promote scientific networking and support already exist...